Dual mode detection and sunlight-driven photocatalytic degradation of tetracycline with tailor-made N-doped carbon dots.

Carbon dots have emerged as one of the most promising materials with various potential applications derived from their unique photophysical and chemical properties. The present work investigates the electrochemical and photochemical properties of one-pot synthesized carbon dots for environmental sustainability. Facile microwave-assisted pyrolysis of urea and glucose yielded nitrogen doped carbon dots (N-doped carbon dots) with blue fluorescence and a quantum yield of 14.9%. As synthesized N- doped carbon dot had intense fluorescence, stability, water solubility, and biocompatibility. In the sensing studies, N-doped carbon dots appeared as a dual sensor for drug tetracycline with excellent sensitivity and selectivity. Beyond sense, the carbon dots have the potential to act as a photocatalyst for the degradation of tetracycline. Further, N-doped carbon dot could bring exhaustive degradation of tetracycline (>95%) within 10 min in the absence of any additives. This is the first time report on the utilization of raw non-metal doped carbon dots as a photocatalyst for the degradation of tetracycline.

Biomass-derived carbon dots as a sensitive and selective dual detection platform for fluoroquinolones and tetracyclines.

A novel carbon dot (CD) was synthesized through the facile and simple hydrothermal method from Curcuma amada, as the precursor for the first time. These CDs with an average diameter of 4.6 nm display blue fluorescence, with excitation/emission maxima at 360/445 nm and a quantum yield of 14.1%. It exhibited high stability under different conditions and was characterized using various techniques. These CDs can be employed as a dual-sensing platform to detect tetracyclines and fluoroquinolones, two antibiotic classes. Even though antibiotics are regarded as an inevitable commodity, overuse and improper management of discarded antibiotics pose a severe threat to the environment. Herein, we developed a dual-sensing, biocompatible sensor with high selectivity and sensitivity to detect antibiotics. CD was employed as a fluorescence probe and detected tetracycline and fluoroquinolone antibiotic through inner filter effect-based fluorescence quenching and hydrogen bonding-based enhancement process, respectively. The linear range was 0-16 µM and the detection limit was 33 nM for tetracycline and 2 nM for fluoroquinolone antibiotic. As an electrochemical probe, CD selectively detected tetracycline with a lower detection limit of 0.5 nM over a linear range of 0-16 µM. Using both methods, a real sample analysis of the developed sensor exhibited accurate reliability and precision.