Detalhe da pesquisa
1.
Crystal Structure of the Human Cannabinoid Receptor CB2.
Cell;
176(3): 459-467.e13, 2019 01 24.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30639103
2.
Renal Mitochondrial ATP Transporter Ablation Ameliorates Obesity-Induced CKD.
J Am Soc Nephrol;
35(3): 281-298, 2024 Mar 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38200648
3.
Myeloid-Cell-Specific IL-6 Signaling Promotes MicroRNA-223-Enriched Exosome Production to Attenuate NAFLD-Associated Fibrosis.
Hepatology;
74(1): 116-132, 2021 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33236445
4.
The effects of acute alcohol administration on circulating endocannabinoid levels in humans.
Addict Biol;
27(5): e13197, 2022 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36001429
5.
Metabolic effects of skeletal muscle-specific deletion of beta-arrestin-1 and -2 in mice.
PLoS Genet;
15(10): e1008424, 2019 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31622341
6.
Interleukin-22 Ameliorates Neutrophil-Driven Nonalcoholic Steatohepatitis Through Multiple Targets.
Hepatology;
72(2): 412-429, 2020 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31705800
7.
Effects of a Peripherally Restricted Hybrid Inhibitor of CB1 Receptors and iNOS on Alcohol Drinking Behavior and Alcohol-Induced Endotoxemia.
Molecules;
26(16)2021 Aug 22.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34443679
8.
Bleomycin Induces Drug Efflux in Lungs. A Pitfall for Pharmacological Studies of Pulmonary Fibrosis.
Am J Respir Cell Mol Biol;
62(2): 178-190, 2020 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31419911
9.
Cannabinoid-1 Receptor Antagonism Improves Glycemic Control and Increases Energy Expenditure Through Sirtuin-1/Mechanistic Target of Rapamycin Complex 2 and 5'Adenosine Monophosphate-Activated Protein Kinase Signaling.
Hepatology;
69(4): 1535-1548, 2019 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30506571
10.
Adipocyte Death Preferentially Induces Liver Injury and Inflammation Through the Activation of Chemokine (C-C Motif) Receptor 2-Positive Macrophages and Lipolysis.
Hepatology;
69(5): 1965-1982, 2019 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30681731
11.
Interactions Between Alcohol and the Endocannabinoid System.
Alcohol Clin Exp Res;
44(4): 790-805, 2020 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32056226
12.
Cannabinoid receptor signaling regulates liver development and metabolism.
Development;
143(4): 609-22, 2016 Feb 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26884397
13.
Disruption of Renal Arginine Metabolism Promotes Kidney Injury in Hepatorenal Syndrome in Mice.
Hepatology;
68(4): 1519-1533, 2018 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29631342
14.
Preclinical toxicity evaluation of JD5037, a peripherally restricted CB1 receptor inverse agonist, in rats and dogs for treatment of nonalcoholic steatohepatitis.
Regul Toxicol Pharmacol;
109: 104483, 2019 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31580887
15.
Network analyses identify liver-specific targets for treating liver diseases.
Mol Syst Biol;
13(8): 938, 2017 08 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28827398
16.
Cannabinoid-1 receptor deletion in podocytes mitigates both glomerular and tubular dysfunction in a mouse model of diabetic nephropathy.
Diabetes Obes Metab;
20(3): 698-708, 2018 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29106063
17.
A peripheral endocannabinoid mechanism contributes to glucocorticoid-mediated metabolic syndrome.
Proc Natl Acad Sci U S A;
112(1): 285-90, 2015 Jan 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25535367
18.
Synthesis of 13 C6 -labeled, dual-target inhibitor of cannabinoid-1 receptor (CB1 R) and inducible nitric oxide synthase (iNOS).
J Labelled Comp Radiopharm;
2018 May 23.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29790591
19.
Overactive cannabinoid 1 receptor in podocytes drives type 2 diabetic nephropathy.
Proc Natl Acad Sci U S A;
111(50): E5420-8, 2014 Dec 16.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25422468
20.
Synthesis of S-2-((S)-3-(4-chlorophenyl)-N'-((4-chlorophenyl)sulfonyl)-4-phenyl-4,5-dihydro-1H-pyrazole-1-carboximidamido)-3-(methyl-d3 )butanamide-d5 , octadeuterated JD5037.
J Labelled Comp Radiopharm;
60(10): 460-465, 2017 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28545167