Detalhe da pesquisa
1.
Disease-specific tau filaments assemble via polymorphic intermediates.
Nature;
625(7993): 119-125, 2024 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38030728
2.
Age-dependent formation of TMEM106B amyloid filaments in human brains.
Nature;
605(7909): 310-314, 2022 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35344985
3.
Data-driven regularization lowers the size barrier of cryo-EM structure determination.
Nat Methods;
2024 Jun 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38862790
4.
New SNCA mutation and structures of α-synuclein filaments from juvenile-onset synucleinopathy.
Acta Neuropathol;
145(5): 561-572, 2023 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36847833
5.
Cryo-EM structures of amyloid-ß filaments with the Arctic mutation (E22G) from human and mouse brains.
Acta Neuropathol;
145(3): 325-333, 2023 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36611124
6.
High-throughput cryo-EM structure determination of amyloids.
Faraday Discuss;
240(0): 243-260, 2022 11 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35913272
7.
Cleaved TMEM106B forms amyloid aggregates in central and peripheral nervous systems.
Acta Neuropathol Commun;
12(1): 99, 2024 Jun 17.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38886865
8.
Tau filaments with the Alzheimer fold in cases with MAPT mutations V337M and R406W.
bioRxiv;
2024 Apr 30.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38746388
9.
Super-resolution imaging unveils the self-replication of tau aggregates upon seeding.
Cell Rep;
42(7): 112725, 2023 07 25.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37393617
10.
Cryo-EM structures of tau filaments from SH-SY5Y cells seeded with brain extracts from cases of Alzheimer's disease and corticobasal degeneration.
FEBS Open Bio;
13(8): 1394-1404, 2023 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37337995
11.
Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife;
112022 03 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35244536
12.
Cryo-EM structures of amyloid-ß 42 filaments from human brains.
Science;
375(6577): 167-172, 2022 Jan 14.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35025654
13.
Seeded assembly in vitro does not replicate the structures of α-synuclein filaments from multiple system atrophy.
FEBS Open Bio;
11(4): 999-1013, 2021 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33548114