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1.
Rev Mal Respir ; 36(4): 477-483, 2019 Apr.
Artigo em Francês | MEDLINE | ID: mdl-31005424

RESUMO

Drainage of primary spontaneous pneumothorax (PSP) may be managed by different techniques and with different types of drain. It is mainly performed in the pneumology department or in the emergency department. The aim of the study was to evaluate the factors that influence the success of PSP drainage. This retrospective, monocentric study performed in University Hospital of Toulouse, included patients with a first episode of PSP requiring drainage. The primary outcome was the rate of success according to the techniques of drainage. Data on the size of the drain (>14F or<14F), the drainage technique (small bore catheter or chest tube drainage) and the drainage department (pneumology or emergency) were collected. One hundred and twenty-four patients had a drainage between 2014 and 2016: the late recurrence free success rate was 59% (n=73). Compared with emergency, drainage in pneumology increased the success rate threefold regardless of the drainage technique (P=0.0001) The success rate was similar whatever the technique used (Seldinger or classic technique) (P=0.31). Success and complications rates were similar whether the drain was large (>14F) or small (<14F) (respectively P=0.99 and P=0.58). In our study, the drainage of PSP in the pneumology department, with a small caliber inserted by the Seldinger technique, was associated with a significantly higher success rate.


Assuntos
Drenagem/métodos , Pneumotórax/diagnóstico , Pneumotórax/terapia , Adulto , Tubos Torácicos/efeitos adversos , Tubos Torácicos/estatística & dados numéricos , Drenagem/efeitos adversos , Drenagem/instrumentação , Desenho de Equipamento/efeitos adversos , Desenho de Equipamento/estatística & dados numéricos , Feminino , Humanos , Masculino , Pneumotórax/epidemiologia , Pneumotórax/patologia , Complicações Pós-Operatórias/diagnóstico , Complicações Pós-Operatórias/epidemiologia , Complicações Pós-Operatórias/etiologia , Prognóstico , Recidiva , Estudos Retrospectivos , Fatores de Risco , Toracentese/efeitos adversos , Toracentese/instrumentação , Toracentese/métodos , Resultado do Tratamento , Adulto Jovem
2.
Br J Sports Med ; 42(6): 452-9, 2008 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-18539659

RESUMO

OBJECTIVE: to determine the incidence, nature and causes of injuries sustained during the International Rugby Board (IRB) Rugby World Cup 2007. DESIGN: Pospective, whole-population survey. POPULATION: 626 international rugby players representing 20 teams competing at the IRB Rugby World Cup 2007 in France. METHODS: The survey followed the international consensus procedures for studies of injuries in rugby union; the main outcome measures were incidence of match and training injuries (number of injuries/1000 player hours), severity (days absence), location, type and cause of injury. RESULTS: the incidence of injuries was 83.9/1000 player-match hours (forwards 84.0; backs 83.7) and 3.5/1000 player-training hours (forwards 3.5; backs 3.6). The average severity of injuries was 14.7 days (forwards 14.0; backs 15.5) during matches and 17.8 (forwards 15.9; backs 19.8) during training. Lower limb muscle and ligament injuries were the main injuries during both matches and training. Most injuries were sustained in the tackle during matches and in full-contact skills activities during training. CONCLUSIONS: This study shows the application of the methodology described in the international consensus statement on injury surveillance studies in rugby union and provides benchmark values for the incidence, severity, nature and causes of match and training injuries sustained during the IRB Rugby World Cup.


Assuntos
Futebol Americano/lesões , Traumatismos em Atletas/epidemiologia , Traumatismos em Atletas/etiologia , Traumatismos em Atletas/fisiopatologia , Comportamento Competitivo/fisiologia , Futebol Americano/fisiologia , Humanos , Incidência , Escala de Gravidade do Ferimento , Educação Física e Treinamento/métodos , Estudos Prospectivos , Fatores de Risco
3.
J Vet Cardiol ; 20(1): 33-44, 2018 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-29191414

RESUMO

INTRODUCTION: The coronary arterial system has been the subject of greater investigation than its venous system due to the importance of human coronary artery disease. With the advent of new percutaneous treatments, the anatomy of the coronary venous system has increasing relevancy. We compared the organization of the coronary venous circulation in three species commonly used in research and compared these to normal humans using both macroscopic anatomic and angiographic studies. ANIMALS: The anatomy of five explanted hearts from healthy dogs, pigs, and sheep were studied macroscopically, and 10 explanted hearts per animal species and 10 clinically normal human were examined by angiography. METHODS: Animal hearts were injected with latex and dissected macroscopically. The coronary venous system of humans was evaluated from clinical angiographic studies. In the animal hearts, a retrograde angiographic study was performed via a Foley catheter in the coronary sinus. RESULTS: The general organization of the coronary venous circulation was similar among humans, dogs, sheep, and pigs. Despite overall similarities to humans, animal hearts demonstrated the absence of the oblique vein of the left atrium and differences in position and organization of venous valves; venous diameters; number of tributary veins; and presence of an anastomosis between the left and right (human anterior and posterior) venous tree. The left azygos of the pig and sheep joined the coronary sinus. CONCLUSIONS: Anatomical differences must be considered when planning biomedical and veterinary studies incorporating cardiac veins. This study provides baseline data regarding structure and organization of the cardiac venous system.


Assuntos
Vasos Coronários/anatomia & histologia , Cães/anatomia & histologia , Ovinos/anatomia & histologia , Suínos/anatomia & histologia , Idoso de 80 Anos ou mais , Anatomia Comparada , Angiografia , Animais , Vasos Coronários/diagnóstico por imagem , Feminino , Humanos , Masculino , Especificidade da Espécie
4.
Eur J Surg Oncol ; 33(1): 114-8, 2007 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-17088039

RESUMO

BACKGROUND: Isolated pelvic perfusion exposes tissue to high drug doses and may benefit patients with advanced malignancy. However, leakage is a limit to this technique. AIMS: The aim of the study is to increase the perfusion ratio between local and systemic compartments on isolated pelvic perfusion. We hypothesised that an inflated pressure-suit placed above the level of aortic and caval stop flow could decrease leakage from the regional to the systemic blood compartment in a bovine model. METHOD: As the size of the pressure-suit was adapted for use in humans, we performed our experimental study on 6 calves which are big enough to fit into the suit. We used an inflated pressure-suit placed at low (40mmHg) and high pressures (125mmHg) above the level of aortic and caval stop-flow. A pharmacokinetic study with cisplatinum was performed in both compartments. RESULTS: After injection of the drug, the mean ratio of drug concentration in the locoregional/systemic compartment was 43.1. After 30min, this mean ratio was 4 and 9.7 for a pressure-suit pressure of 40mmHg and 125mmHg, respectively. At pressure-suit pressures of 40mmHg and 125mmHg, pelvic perfusion achieved pelvic/systemic exposure ratios of 5.9 and 14.9 at 30min, respectively. Leakage at 30min was higher when the pressure-suit was inflated at low pressure (40mmHg, mean 18%). When the pressure-suit was inflated at high pressure, leakage was lower (125mmHg, mean 7%). CONCLUSIONS: The pressure-suit increased the perfusion ratio between pelvic and systemic compartments in a bovine model.


Assuntos
Antineoplásicos/administração & dosagem , Quimioterapia do Câncer por Perfusão Regional/instrumentação , Cisplatino/administração & dosagem , Trajes Gravitacionais , Neoplasias Experimentais/tratamento farmacológico , Neoplasias Pélvicas/tratamento farmacológico , Animais , Antineoplásicos/farmacocinética , Bovinos , Cisplatino/farmacocinética , Modelos Animais de Doenças , Desenho de Equipamento , Estudos de Viabilidade , Neoplasias Experimentais/metabolismo , Neoplasias Pélvicas/metabolismo , Resultado do Tratamento
5.
J Vet Cardiol ; 19(3): 293-298, 2017 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-28576478

RESUMO

Intracardiac echocardiography (ICE) is used in humans for percutaneous interventional procedures, such as transcatheter device closures. Intracardiac echocardiography provides high-resolution imaging of cardiac structures with two-dimensional, M-mode, Doppler, and also three-dimensional modalities. The present report describes application of ICE during transcatheter occlusion of patent ductus arteriosus using a canine ductal occluder in a dog for which transesophageal echocardiography could not provide an optimal acoustic window.


Assuntos
Doenças do Cão/cirurgia , Permeabilidade do Canal Arterial/veterinária , Ecocardiografia Transesofagiana/veterinária , Dispositivo para Oclusão Septal/veterinária , Animais , Cães , Permeabilidade do Canal Arterial/cirurgia , Permeabilidade do Canal Arterial/terapia , Ecocardiografia , Feminino , Resultado do Tratamento , Ultrassonografia de Intervenção/veterinária
6.
Arch Mal Coeur Vaiss ; 99(5): 413-8, 2006 May.
Artigo em Francês | MEDLINE | ID: mdl-16802727

RESUMO

This study was undertaken to develop a dilated valved conduit for reconstruction of the right ventricular outflow tract in the animal. The conduits were made by sewing a valved tube (Medtronic Inc) inside a vascular stent (Numed Inc). After preparation, they were inserted surgically in five lambs. The conduits were then dilated 6 weeks and 3 months after their implantation. Before sacrificing the animals at 3 months, a 22 mm valved stent was implanted percutaneously inside the surgical conduits. One animal died suddenly due to kinking of the conduit. Balloon dilatation was performed in the surviving animals. The first dilatation only had a modest impact on valvular function but it was much aggravated after the second dilatation. A valved stent was successfully inserted percutaneously. At sacrifice, all the conduits were completely engulfed in an intense fibrosis. In conclusion, a valved biological conduit for reconstruction of the right ventricular ejection tract has been developed and can be dilated sequentially to follow growth. The new product could have an important role to play in the management of congenital malformations involving the right ventricular outflow tract.


Assuntos
Cateterismo , Próteses Valvulares Cardíacas , Ventrículos do Coração/cirurgia , Stents , Animais , Estudos de Avaliação como Assunto , Cardiopatias Congênitas/terapia , Modelos Animais , Ovinos , Obstrução do Fluxo Ventricular Externo/terapia
7.
Arch Mal Coeur Vaiss ; 99(2): 95-101, 2006 Feb.
Artigo em Francês | MEDLINE | ID: mdl-16555691

RESUMO

BACKGROUND: informed consent is a fundamental and legal obligation for each interventional cardiologist. The effect of consent form describing risks of invasive procedure on anxiety is controversial. This trial was aimed to assess the added value of video information to the standard informed consent process. METHODS: 200 consecutive patients undergoing coronary angiography were enrolled. The first one hundred were assigned to conventional education conducted by the physician (no video group) and the second one hundred had consent obtained in the conventional manner assisted by video information (video group). The outcome variables for this comparison consisted of a standard anxiety score (Spielberger Statement Anxiety Inventory questionnary) plus hemodynamics measurements of heart rate, systolic and diastolic blood pressure obtained at baseline and immediately after written informed consent In addition, before discharge, patients graded the tolerability and satisfaction on a 4-point scale. RESULTS: The groups were similar with regard to their baseline characteristics and anxity score (37+23 vs 37+23). Patients who had not had prior experience of catheterization had higher baseline anxiety than those who had prior angiography (45 + 22 vs 31 + 20; p = 0.027). Patients who watched the video were significantly less anxious after informed consent (28 + 21 vs 34 + 22; p = 0.048) and had a significantly lower heart rate (65 + 10 vs 71 + 12; p = 0.03). The benefits of video information were especially prominent in those with higher anxiety scores at baseline (score after 45 + 24 vs 57 + 26; p = 0.046). Tolerability were higher in the video group compared with no video group (98% vs 86%; p = 0.003). Finally, satisfaction of information for informed consent process was higher in video group than in no video group (99% vs 76%; p = 0.001). CONCLUSION: a video information decreased anxiety level after written informed consent and improved tolerability and satisfaction scales in patients undergoing coronary angiography. The most likely to benefit from video information are patients with higher anxiety level at baseline. Beneficial effect on informed refusal should be investigated in larger population.


Assuntos
Angiografia Coronária/psicologia , Educação de Pacientes como Assunto/métodos , Gravação de Videoteipe , Adaptação Psicológica , Idoso , Ansiedade , Feminino , França , Humanos , Consentimento Livre e Esclarecido , Masculino , Satisfação do Paciente
8.
Ann Cardiol Angeiol (Paris) ; 54(2): 68-73, 2005 Mar.
Artigo em Francês | MEDLINE | ID: mdl-15828460

RESUMO

UNLABELLED: The GRACE registry provides the opportunity to analyse management of acute coronary syndromes in the real word and the impact of hospital characteristics. In this setting, we compare the activity of a new coronary intensive care unit with regional data. METHODS: From January 2000 to December 2003, 376 eligible patients were involved (22% of regional inclusion). GRACE standard diagnosis were the following, for our centrer (for the cluster): ST elevation myocardial infarction 28% (37%), non-ST elevation myocardial infarction 32% (31%), unstable angina 33% (24%). Demographic characteristics were similar with a median age of 64 (vs 66) and a large majority of male (74 vs 81%). Medical history and cardiovascular risk factors were comparable. Predictors of hospital mortality were observed at the same rate: cardiogenic shock (3 vs 3%), congestive heart failure > Killip 2 (4 vs 4%), left ventricular ejection fraction (LVEF) lower than 40% (17 vs 16%), recurrent ischemic symptoms (8 vs 8%). Coronary artery bypass grafts were required in 5% (vs 2%). RESULTS: Drugs prescription rates were similar: aspirin at admission (95%) and at discharge (95%), betablocker at admission (70%) and at discharge (85%), statin at admission (< 30% in 2000, > 60% in 2003) and at discharge (< 60% in 2000 and > 80% in 2003), ticlopidin-clopidogrel at admission (< 20% in 2000 and > 40% in 2003), ACE inhibitor for LVEF < 40%, intravenous GPIIblIIa, and low molecular weight heparin (90%). Cardiac catheterisation (90%) and percutaneous coronary interventions (80%) were performed at the same rates in our center and in the cluster. Hospital death was similar (2 vs 4%). Discharge status was home for a large majority of patients (63 vs 76%). The median length of stay was five days and shorter than three days for patients with unstable angina. CONCLUSION: Based on GRACE registry data, the present evaluation revealed that our new center offered evidence-based medical and interventional therapy in patients with acute coronary syndromes at the same level than experienced institutions with similar results for hospital death and length of stay.


Assuntos
Angina Instável/terapia , Unidades de Cuidados Coronarianos , Eletrocardiografia , Medicina Baseada em Evidências , Infarto do Miocárdio/terapia , Sistema de Registros , Idoso , Angina Instável/complicações , Angina Instável/diagnóstico , Angina Instável/tratamento farmacológico , Angina Instável/mortalidade , Angioplastia Coronária com Balão , Feminino , França , Mortalidade Hospitalar , Hospitais Universitários , Humanos , Tempo de Internação , Masculino , Pessoa de Meia-Idade , Infarto do Miocárdio/complicações , Infarto do Miocárdio/diagnóstico , Infarto do Miocárdio/tratamento farmacológico , Infarto do Miocárdio/mortalidade , Prognóstico , Fatores de Risco , Síndrome
9.
Atherosclerosis ; 73(1): 33-7, 1988 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-3178929

RESUMO

The morphologic, biochemical, and mechanical abnormalities of connective tissue fibrous proteins in Marfan's syndrome have been well studied, and their role in cardiovascular complications is well accepted. Less is known, however, about the state of the amorphous components of the aortic connective tissue. In the course of a study of transmural transport in blood vessels, we have had the opportunity to study dystrophic aorta from two young men who survived elective surgery; both with aortic insufficiency (AI) histologically compatible with Marfan's syndrome. One had recurrent chronic dissecting aneurysm (RCDA) as well. The aorta of the first (but not the second) was histologically compatible with Marfan's syndrome. Fresh specimens of intact ascending aorta were incubated in Krebs solution, pH 7.4, containing 125I-labelled bovine serum albumin for 2 h at 37 degrees C. The samples were then frozen, and serially sectioned in the plane of the lumenal surface. The radioactivity of the 20-micron thick sections was then determined, and expressed as a tissue/labelled solution concentration ratio. Transmural profiles of these ratios revealed no difference between the aorta of the RCDA patient with non-specific aortic dystrophy, and that of a 70-year-old man undergoing aortocoronary bypass. However, in the patient with aortic histology compatible with Marfan's syndrome, the average media concentration ratio was 5-fold less (4% vs. 20%).


Assuntos
Síndrome de Marfan/metabolismo , Músculo Liso Vascular/metabolismo , Soroalbumina Bovina , Adulto , Aorta/metabolismo , Aorta/patologia , Transporte Biológico , Humanos , Radioisótopos do Iodo , Masculino , Síndrome de Marfan/patologia , Músculo Liso Vascular/patologia
10.
Chest ; 102(2): 380-6, 1992 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-1643918

RESUMO

We have developed novel implantable Doppler microprobes to monitor beat-by-beat stroke volume and cardiac output (CO) after cardiac surgery. In 11 adults undergoing either coronary artery bypass grafting (n = 6) or valve replacement (n = 5), Doppler microprobes were implanted on the ascending aorta or the main pulmonary artery to measure aortic blood flow (ABF) or pulmonary artery blood flow (PBF). The diameters of both vessels were determined before surgery using two-dimensional echocardiography. Stroke volume was obtained from velocity tracings measured by a 4-MHz zero-crossing pulsed Doppler flowmeter. Simultaneous measurements of Doppler and thermodilution CO (TDCO) were compared. We found the following: ABF = 1.03 TDCO - 0.22 L/min (r = 0.89); while PBF = 0.69 TDCO - 1.24 L/min (r = 0.75). Furthermore, peak flow velocity and maximum acceleration of blood in the ascending aorta were measured after inotropic stimulation with dobutamine; both values increased significantly from control values (25.2 +/- 6.1 percent and 44.6 +/- 8.6 percent, respectively, at 7.5 micrograms/kg/min). We conclude that implanted aortic Doppler microprobes provide a sensitive and reliable method to measure aortic blood flow velocity after surgery and then allow monitoring of stroke volume and CO and analysis of left ventricular function after cardiac surgery.


Assuntos
Aorta/diagnóstico por imagem , Débito Cardíaco/fisiologia , Ponte de Artéria Coronária , Ecocardiografia Doppler/instrumentação , Próteses Valvulares Cardíacas , Artéria Pulmonar/diagnóstico por imagem , Função Ventricular Esquerda/fisiologia , Aorta/fisiopatologia , Velocidade do Fluxo Sanguíneo/fisiologia , Ecocardiografia Doppler/métodos , Ecocardiografia Doppler/estatística & dados numéricos , Desenho de Equipamento , Humanos , Análise dos Mínimos Quadrados , Pessoa de Meia-Idade , Contração Miocárdica/efeitos dos fármacos , Contração Miocárdica/fisiologia , Período Pós-Operatório , Artéria Pulmonar/fisiopatologia , Análise de Regressão , Termodiluição
11.
J Thorac Cardiovasc Surg ; 105(2): 278-80, 1993 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-8429655

RESUMO

Classic surgical interruption of patent ductus arteriosus was partially replaced by transcatheter endovascular closure in 1971. We describe a new technique for ductus closure by video-assisted thoracoscopic surgical interruption, derived from video-assisted endoscopic surgery. With the patient under general anesthesia and intubated, two 5 mm holes were made through the left thoracic wall. A video camera and specially devised surgical tools were introduced; such as scissors, dissectors, and clip appliers. The ductus was dissected, and two titanium clips were applied, completely interrupting the ductus. Thirty-eight patients were operated on from April 1991 to April 1992. Mean age was 23.3 months (range 1.5 to 90 months) and mean weight was 9.5 kg (range 2.4 to 25 kg). Six had associated lesions not necessitating immediate surgical treatment. All had successful closure of the patent ductus with the video-assisted technique, but two needed two such procedures, one because of incomplete immediate ductus closure and one because of partial opening of the clip after 24 hours. One patient had recurrent laryngeal nerve injury and four had pneumothorax on the left side. The usual hospital stay was 2 or 3 days. There were no other complications and no deaths. Video-assisted thoracoscopic surgical interruption was a rapid, safe, and successful technique for closure of the patent ductus arteriosus. Better dissection of the ductus decreased the risk of recurrent laryngeal nerve injury and that of clip opening. In the last 26 patients, in whom a 2 mm multiperforated catheter was used for chest drainage during the first hours, no pneumothoraces occurred. Video-assisted thoracoscopic interruption of the patent ductus arteriosus is feasible in low-weight infants, whereas transcatheter endovascular closure of the ductus usually is not possible. The technique will be applied to premature infants with new instruments designed for the size of these patients.


Assuntos
Permeabilidade do Canal Arterial/cirurgia , Toracoscopia/métodos , Criança , Pré-Escolar , Permeabilidade do Canal Arterial/diagnóstico por imagem , Ecocardiografia Doppler , Humanos , Lactente , Tempo de Internação , Reoperação , Toracoscopia/efeitos adversos , Gravação em Vídeo
12.
J Thorac Cardiovasc Surg ; 91(2): 215-24, 1986 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-3945089

RESUMO

The effectiveness of a water-soluble C-12 alkyl sulfate (T6) (U.S. Patent No. 4,323,358) in retarding bioprosthetic calcification was evaluated in 23 porcine-valved conduits (13 T6-treated conduits and 10 controls) implanted in young sheep between the right ventricle and the pulmonary trunk. The grafts were divided into three groups according to the period of function: Group I, less than 2 months; Group II, 2 to 4 months; and Group III, 5 to 7 months. In Group I (four T6 and four controls), endocarditis occurred in five cases. In Group II (three T6 and three controls), four conduits showed severe fibrous peel ingrowth. In Group III (six T6 and three controls), fibrous peel was the main feature in four conduits and calcium deposits occurred in the porcine aortic wall in all cases, with cusp involvement in two; in both T6-treated and control conduits, chemical analysis showed a much lower calcium content of the cusps (8.45 +/- 80 versus 2.95 +/- 1.52 mg/gm dry weight, respectively) than that reported in other animal or human explants. The grade of calcification in control and T6-treated conduits was equal on x-ray analysis, and no differences in calcification patterns were noted on electron microscopy. This experimental model shows a low degree of cusp calcification and no significant differences between T6-treated and control conduits. Peel formation markedly interferes with performance of the porcine-valved conduit. The results of this analysis indicate that valved conduits are not the optimum model for evaluating calcium-retardant agents in biological valves.


Assuntos
Bioprótese/efeitos adversos , Calcinose/prevenção & controle , Próteses Valvulares Cardíacas/efeitos adversos , Dodecilsulfato de Sódio , Ésteres do Ácido Sulfúrico , Ácidos Sulfúricos , Tensoativos , Animais , Doenças da Aorta/patologia , Doenças da Aorta/prevenção & controle , Calcinose/patologia , Endocardite Bacteriana/etiologia , Endocardite Bacteriana/patologia , Ovinos , Suínos , Fatores de Tempo
13.
J Thorac Cardiovasc Surg ; 82(3): 423-8, 1981 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-7278332

RESUMO

From 1972 to September, 1979, 20 patients underwent transplantation of the anomalous left coronary artery to the aorta, either directly or via a graft. Correction of ischemia-induced mitral insufficiency was associated in eight patients and a postinfarction left ventricular scar was excised in 12. Operative mortality was high among patients under 1 year of age (4/5). Among older children it was 15%. There were not late deaths among patients surviving the operation (mean follow-up 3 years). All but one had marked clinical improvement and reduction of cardiomegaly. Eleven patients underwent angiographic control, with a patent graft or anastomosis demonstrated in every case. Operation is advocated for patients over 1 year of age. The best treatment of symptomatic infants remains controversial.


Assuntos
Anomalias dos Vasos Coronários , Aorta/cirurgia , Aortografia , Criança , Pré-Escolar , Angiografia Coronária , Vasos Coronários/cirurgia , Feminino , Humanos , Lactente , Masculino , Métodos , Prognóstico , Veia Safena/transplante , Artéria Subclávia/transplante
14.
J Thorac Cardiovasc Surg ; 110(6): 1681-4; discussion 1684-5, 1995 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-8523880

RESUMO

Video-assisted thoracoscopic surgical interruption for patient ductus arteriosus is a well-standardized procedure already described. We present our entire series of such cases, from the first case (performed on Sept. 5, 1991) to March 1, 1995. Two hundred thirty patients in a variety of age groups underwent video-assisted interruption: younger than 6 months (70 patients, 30%), 6 to 48 months (123 patients, 54%), and older than 48 months (37 patients, 16%). The mean weight was 12.6 kg (range 1.2 to 65 kg). Thirty-nine patients had symptomatic pulmonary hypertension. Associated intracardiac anomalies included atrial septal defect (three), ventricular septal defect (five), and anomalous pulmonary venous return (one). All patients underwent video-assisted interruption of the patient ductus arteriosus with two titanium clips. Closure was evaluated by postoperative echocardiography before extubation. Five patients had a persistent patent ductus after video-assisted interruption, all early in our experience and related to insufficient dissection resulting in inadequate clip placement. Four patients had successful immediate clip repositioning (three by video-assisted interruption and one by thoracotomy). Subsequent echocardiography revealed persistent closure in these patients. A persistent patent ductus arteriosus with minimal flow was discovered in one patient without symptoms after discharge. Recurrent laryngeal nerve dysfunction was noted in six patients (2.6%, five transient and one persistent). There were no deaths, hemorrhages, transfusions required, or chylothoraces in this series. Mean operative time was 20 +/- 15 minutes, and hospital stay averaged 48 hours for patients younger than 6 months and 72 hours for patients older than 6 months. This is a safe, rapid, cost-effective technique that results in excellent results and a shortened hospital stay. Video-assisted interruption represents the technique of choice for closure of a patient ductus arteriosus.


Assuntos
Permeabilidade do Canal Arterial/cirurgia , Endoscopia/métodos , Toracoscopia/métodos , Pré-Escolar , Permeabilidade do Canal Arterial/complicações , Permeabilidade do Canal Arterial/diagnóstico por imagem , Permeabilidade do Canal Arterial/epidemiologia , Ecocardiografia Doppler em Cores , Endoscopia/estatística & dados numéricos , Cardiopatias Congênitas/complicações , Humanos , Lactente , Tempo de Internação , Complicações Pós-Operatórias/epidemiologia , Fatores de Tempo , Gravação em Vídeo
15.
Ann Thorac Surg ; 64(5): 1492-4, 1997 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-9386738

RESUMO

A videothoracoscopic surgical technique for closure of patent ductus arteriosus in children is described. Only three ports of access are necessary to dissect the patent ductus arteriosus from the surrounding tissues and to apply the two titanium clips. The advantages given are the technique's low morbidity, lack of mortality, and reliable closure. We believe that the videothoracoscopic surgical approach is the technique of choice for patent ductus arteriosus closure in children.


Assuntos
Procedimentos Cirúrgicos Cardíacos/métodos , Permeabilidade do Canal Arterial/cirurgia , Endoscopia/métodos , Toracoscopia , Humanos , Lactente , Cuidados Pós-Operatórios , Gravação em Vídeo
16.
Ann Thorac Surg ; 71(5 Suppl): S289-92, 2001 May.
Artigo em Inglês | MEDLINE | ID: mdl-11388207

RESUMO

BACKGROUND: The Pericarbon pericardial bioprosthesis, at the time of its creation, showed a breakthrough in terms of low calcification deposit rate, absence of valvular tears, and durability. The purpose of this study was to evaluate results after 10 years. METHODS: From September 1988 to December 1997, 277 patients received a total of 287 Pericarbon pericardial valves. There were 224 (80.8%) isolated aortic valve replacements (AVR), 39 isolated mitral valve replacements (MVR), 1 tricuspid valve replacement, 3 pulmonary valve replacements, and 10 aortic and mitral valve replacements. The total cumulative follow-up was 1,221.42 patient-years (mean 4.9+/-2.6 years). RESULTS: Overall hospital mortality was 10.1%. The overall patient survival at 10.8 years was 55.8%+/-4.2%, for AVR it was 60.0%+/-4.5%, and for MVR it was 46.5%+/-11.9%. The freedom from valve-related death for the overall population at 10.8 years was 98.0%+/-1.0%, for AVR 97.6%+/-1.1%, and for MVR 100%. The overall freedom from structural valve deterioration was 96.6%+/-2.4%, for AVR 96.1%+/-2.7%, and for MVR 100%. The overall freedom from embolic events was 96.0%+/-1.5%, for AVR 96.0%+/-1.6%, and for MVR 100%. The overall freedom from reoperation was 88.1%+/-3.8%, for AVR 89.9%+/-4.2%, and for MVR 80.6%+/-7.3%. CONCLUSIONS: These results show that over a period of up to 10 years, the Pericarbon pericardial bioprosthesis is an excellent and safe valve substitute. Developing a detoxification process aimed at improving the biological behavior of the glutaraldehyde-tanned valve may increase those advantages.


Assuntos
Bioprótese , Doenças das Valvas Cardíacas/cirurgia , Próteses Valvulares Cardíacas , Adulto , Idoso , Idoso de 80 Anos ou mais , Valva Aórtica/cirurgia , Causas de Morte , Feminino , Seguimentos , Doenças das Valvas Cardíacas/mortalidade , Mortalidade Hospitalar , Humanos , Masculino , Pessoa de Meia-Idade , Valva Mitral/cirurgia , Complicações Pós-Operatórias/mortalidade , Desenho de Prótese , Falha de Prótese , Valva Pulmonar/cirurgia , Taxa de Sobrevida , Valva Tricúspide/cirurgia
17.
Ann Thorac Surg ; 63(4): 1162-3, 1997 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-9124929

RESUMO

A patient with a left coronary calcified embolus causing acute myocardial dysfunction immediately after aortic valve replacement is described. Prompt diagnosis by transesophageal echocardiogram was made, which led to removal of the embolus and a subsequent satisfactory course.


Assuntos
Estenose da Valva Aórtica/cirurgia , Calcinose/complicações , Calcinose/cirurgia , Doença das Coronárias/etiologia , Embolia/etiologia , Complicações Intraoperatórias , Idoso , Doença das Coronárias/cirurgia , Embolia/cirurgia , Doenças das Valvas Cardíacas/cirurgia , Humanos , Complicações Intraoperatórias/cirurgia , Masculino
18.
Ann Thorac Surg ; 72(4): 1358-61, 2001 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-11603461

RESUMO

BACKGROUND: In patients who undergo left ventricular retraining, multiple reoperations are often necessary to adjust the pulmonary artery banding. The availability of a percutaneously adjustable band would be very useful. METHODS: Ten lambs (10 to 25 kg) underwent pulmonary artery banding using a new device, 7 by thoracotomy and 3 by thoracoscopy. The possibility of percutaneously adjusting the band was evaluated immediately after operation in 10 animals and at 3 months in 8 animals. RESULTS: One death occurred on the day of the procedure from displacement of the device and another death was from infection. Immediate hemodynamic studies proved the feasibility of increasing right ventricular afterload in a precise and reversible way. After 3 months the band could still be precisely loosened or tightened in all but 1 animal. Autopsy revealed that all the devices were in the correct position and no fibrosis or adhesions were present around the devices, and there was no residual stenosis noted on the pulmonary artery. CONCLUSIONS: This new device may be a valuable alternative to the repeated pulmonary artery banding needed for ventricular preparation.


Assuntos
Cateteres de Demora , Cardiopatias Congênitas/cirurgia , Pulmão/irrigação sanguínea , Nylons , Complicações Pós-Operatórias/cirurgia , Implantação de Prótese , Artéria Pulmonar/cirurgia , Animais , Pressão Sanguínea/fisiologia , Desenho de Prótese , Ovinos , Sístole/fisiologia , Função Ventricular Direita/fisiologia
19.
Int J Cardiol ; 22(2): 221-8, 1989 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-2644176

RESUMO

We report 2 cases of extrathoracic heart (ectopia cordis) operated on a few hours after birth at Laennec Hospital, Paris. The first patient had an associated diastasis of the rectus muscles. The second one, in whom diagnosis was made by ultrasound during fetal life, had a normal abdominal wall. In both cases it was possible to accommodate the heart in the left pleural cavity after a wide dissection of the posterior mediastinum. Both babies, however, died soon after the operation. Double outlet right ventricle was found in both. We have reviewed those cases previously described and discuss the importance of prenatal echocardiographic diagnosis in this rare condition.


Assuntos
Cardiopatias Congênitas/cirurgia , Feminino , Parada Cardíaca/patologia , Átrios do Coração/patologia , Cardiopatias Congênitas/diagnóstico , Cardiopatias Congênitas/patologia , Ventrículos do Coração/patologia , Humanos , Recém-Nascido , Masculino , Complicações Pós-Operatórias/patologia , Gravidez , Diagnóstico Pré-Natal , Retalhos Cirúrgicos , Ultrassonografia
20.
Int J Cardiol ; 80(2-3): 187-92, 2001.
Artigo em Inglês | MEDLINE | ID: mdl-11578713

RESUMO

BACKGROUND: We evaluated the feasibility, safety, procedural cost-effectiveness, radiation dose and time and 1-year target vessel revascularization rate of direct unprotected mounted stenting without previous balloon dilatation (DS) in native coronary artery lesions. METHODS: DS was attempted in 119 patients; 39 had a recent myocardial infarction, 62 had unstable angina, and 18 had stable angina. The clinical follow-up was obtained at 14+/-5 months (range 6 to 24 months). These results were compared with those for a consecutive group of 160 patients matched for type and length of lesions and who had a stent only if the post-balloon residual stenosis was >30%. RESULTS: The feasibility of DS was 112/119 (94%). The number of inflations, the length of the stent/length of the lesion ratio, the time and the dose of radiation were dramatically lower in the DS group (P<0.001). DS conferred a slight reduction in procedure-related cost [$820+/-157 for DS vs. 894+/-427 for standard dilatation (SD) per patient]. The 1-year target vessel revascularization rate was similar in both groups [nine (8%) for DS vs. 17 (11%) patients for SD, ns]. CONCLUSIONS: DS is feasible and safe in selected coronary lesions. This method provides a low rate of repeat revascularization and reduces the time and the dose of radiation compared with the standard approach.


Assuntos
Reestenose Coronária/prevenção & controle , Estenose Coronária/terapia , Stents , Idoso , Angioplastia Coronária com Balão/efeitos adversos , Angioplastia Coronária com Balão/economia , Estenose Coronária/economia , Análise Custo-Benefício , Estudos de Viabilidade , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Stents/efeitos adversos , Stents/economia , Fatores de Tempo , Resultado do Tratamento
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