Detalhe da pesquisa
1.
Human and Insect Cell-Produced Recombinant Adeno-Associated Viruses Show Differences in Genome Heterogeneity.
Hum Gene Ther;
33(7-8): 371-388, 2022 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35293222
2.
The SSV-Seq 2.0 PCR-Free Method Improves the Sequencing of Adeno-Associated Viral Vector Genomes Containing GC-Rich Regions and Homopolymers.
Biotechnol J;
16(1): e2000016, 2021 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33064875
3.
Single-Stranded DNA Virus Sequencing (SSV-Seq) for Characterization of Residual DNA and AAV Vector Genomes.
Methods Mol Biol;
1950: 85-106, 2019.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30783969
4.
Accurate Titration of Infectious AAV Particles Requires Measurement of Biologically Active Vector Genomes and Suitable Controls.
Mol Ther Methods Clin Dev;
10: 223-236, 2018 Sep 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30112419
5.
RNA-Seq Analysis of an Antisense Sequence Optimized for Exon Skipping in Duchenne Patients Reveals No Off-Target Effect.
Mol Ther Nucleic Acids;
10: 277-291, 2018 Mar 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29499940
6.
Accurate Identification and Quantification of DNA Species by Next-Generation Sequencing in Adeno-Associated Viral Vectors Produced in Insect Cells.
Hum Gene Ther Methods;
28(3): 148-162, 2017 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28463571
7.
Advanced Characterization of DNA Molecules in rAAV Vector Preparations by Single-stranded Virus Next-generation Sequencing.
Mol Ther Nucleic Acids;
4: e260, 2015 Oct 27.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26506038
8.
Short-lived recombinant adeno-associated virus transgene expression in dystrophic muscle is associated with oxidative damage to transgene mRNA.
Mol Ther Methods Clin Dev;
2: 15010, 2015.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26029721