[Hyperplasia in ectopic prostate tissue with chronic inflammation in the bladder: A case report and literature review].

Objective： To improve the understanding of ectopic prostatic hyperplasia tissue with chronic inflammation, and to explore its occurrence mechanism and diagnosis and treatment. Methods： The clinical data of a patient with ectopic prostate tissue admitted to our hospital were analyzed and the literature was reviewed. Results： This paper reports a 71 year old male patient with benign hyperplasia in ectopic prostate tissue with chronic inflammation in bladder. This patient underwent a transperineal biopsy of prostate and transurethral resection of bladder mass because the imaging examination indicated a space-occupying mass and abnormally elevated blood prostate-specific antigen (PSA). During the operation, an isolated, smooth solid nodule was observed in the middle of the interureteric ridge in the bladder. Postoperative pathological examination of prostate biopsy specimen and bladder mass specimen showed benign hyperplasia in prostate tissue accompanied with local chronic inflammation. The patient received the postoperative follow-up for half a year, and no recurrence was observed. Conclusion： Intravesical ectopic prostatic hyperplasia tissue is clinically rare, and cases with chronic inflammation are even more rare. Diagnosis depends on imaging examination, and diagnosis is based on pathology. Surgical complete resection is currently the preferred treatment option.

Impact of Laparoscopic Partial Nephrectomy and Open Partial Nephrectomy on Outcomes of Clear Cell Renal Cell Carcinoma.

Objective: To analyze the impact of laparoscopic partial nephrectomy (LPN) and open partial nephrectomy (OPN) on outcomes of complex clear cell renal cell carcinoma (ccRCC). Methods: A total of 132 high-complex ccRCC patients with a Radius Exophytic Nearness Anterior Location (R.E.N.A.L) score ≥7 enrolled in our hospital between January 2018 and June 2020 were matched and assigned to an LPN group (given LPN treatment) and an OPN group (given OPN treatment), with 66 cases in each group. Two weeks and 3 months after the operation, the renal indexes, inflammatory factors, basic perioperative conditions, and incidence of complications were compared. Results: Two weeks after the operation, the levels of SCr and CysC were elevated, with higher levels observed in the LPN group (all P < 0.05), and the eGFR levels were reduced, with a lower result in the LPN group. Three months after the operation, the two groups observed decreased levels of SCr and CysC, and an increased level of eGFR; moreover, the decreased SCr and CysC levels were still higher, and the increased eGFR was lower than those before the operation (P < 0.05). The levels of CRP and TNF-α in the two groups increased after the operation, with a lower outcome in the LPN group (P < 0.05). Moreover, the LPN group had less intraoperative blood loss and shorter postoperative length of hospital stay but longer blocking time compared to the OPN group (P < 0.05). Patients in the LPN group were recorded with a lower complication incidence compared with the OPN group (3.03 vs. 15.15%, P < 0.05). Conclusion: Both LPN and OPN enjoy significant efficacy in the treatment of complex ccRCC and effectively protect renal function. Moreover, LPN is a more acceptable option for complex ccRCC due to its numerous benefits in postoperative stress response, complications, recovery. which is worthy of promotion with safety and feasibility.