Detalhe da pesquisa
1.
Population pharmacokinetics and humanized dosage regimens matching the peak, area, trough, and range of amikacin plasma concentrations in immune-competent murine bloodstream and lung infection models.
Antimicrob Agents Chemother;
68(3): e0139423, 2024 Mar 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38289076
2.
Pharmacodynamic evaluation of ceftriaxone single-dose therapy (0.125-1 g) to eradicate ceftriaxone-susceptible and ceftriaxone-resistant Neisseria gonorrhoeae strains in a hollow fibre infection model for gonorrhoea.
J Antimicrob Chemother;
79(5): 1006-1013, 2024 May 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38497988
3.
Individual Components of Polymyxin B Modeled via Population Pharmacokinetics to Design Humanized Dosage Regimens for a Bloodstream and Lung Infection Model in Immune-Competent Mice.
Antimicrob Agents Chemother;
67(5): e0019723, 2023 05 17.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37022153
4.
Combination Therapy to Kill Mycobacterium tuberculosis in Its Nonreplicating Persister Phenotype.
Antimicrob Agents Chemother;
66(10): e0069522, 2022 10 18.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36165631
5.
Dose Fractionation of Moxifloxacin for Treatment of Tuberculosis: Impact of Dosing Interval and Elimination Half-Life on Microbial Kill and Resistance Suppression.
Antimicrob Agents Chemother;
65(4)2021 03 18.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33468465
6.
Polymyxin B Pharmacodynamics in the Hollow-Fiber Infection Model: What You See May Not Be What You Get.
Antimicrob Agents Chemother;
65(8): e0185320, 2021 07 16.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34097487
7.
Building Optimal Three-Drug Combination Chemotherapy Regimens To Eradicate Mycobacterium tuberculosis in Its Slow-Growth Acid Phase.
Antimicrob Agents Chemother;
65(10): e0069321, 2021 09 17.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34339275
8.
The Funnel: a Screening Technique for Identifying Optimal Two-Drug Combination Chemotherapy Regimens.
Antimicrob Agents Chemother;
65(2)2021 01 20.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33199386
9.
Emergence of Resistance to Ceftazidime-Avibactam in a Pseudomonas aeruginosa Isolate Producing Derepressed blaPDC in a Hollow-Fiber Infection Model.
Antimicrob Agents Chemother;
65(6)2021 05 18.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33782013
10.
Building Optimal Three-Drug Combination Chemotherapy Regimens.
Antimicrob Agents Chemother;
64(11)2020 10 20.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32900682
11.
Developing New Drugs for Mycobacterium tuberculosis Therapy: What Information Do We Get from Preclinical Animal Models?
Antimicrob Agents Chemother;
64(12)2020 11 17.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32958720
12.
First Penicillin-Binding Protein Occupancy Patterns for 15 ß-Lactams and ß-Lactamase Inhibitors in Mycobacterium abscessus.
Antimicrob Agents Chemother;
65(1)2020 12 16.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33106266
13.
Effect of Moxifloxacin plus Pretomanid against Mycobacterium tuberculosis in Log Phase, Acid Phase, and Nonreplicating-Persister Phase in an In Vitro Assay.
Antimicrob Agents Chemother;
63(1)2019 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30397058
14.
Pharmacodynamics of Ceftazidime plus Avibactam against KPC-2-Bearing Isolates of Klebsiella pneumoniae in a Hollow Fiber Infection Model.
Antimicrob Agents Chemother;
63(8)2019 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31160285
15.
Generating Robust and Informative Nonclinical In Vitro and In Vivo Bacterial Infection Model Efficacy Data To Support Translation to Humans.
Antimicrob Agents Chemother;
63(5)2019 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30833428
16.
GC-072: A Novel Therapeutic Candidate for Oral Treatment of Melioidosis and Infections Caused by Select Biothreat Pathogens.
Antimicrob Agents Chemother;
63(12)2019 09 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31548183
17.
Comparable Efficacy and Better Safety of Double ß-Lactam Combination Therapy versus ßLactam plus Aminoglycoside in Gram-Negative Bacteria in Randomized, Controlled Trials.
Antimicrob Agents Chemother;
63(7)2019 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30988147
18.
Determination of the Dynamically Linked Indices of Fosfomycin for Pseudomonas aeruginosa in the Hollow Fiber Infection Model.
Antimicrob Agents Chemother;
62(6)2018 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29581114
19.
The Combination of Fosfomycin plus Meropenem Is Synergistic for Pseudomonas aeruginosa PAO1 in a Hollow-Fiber Infection Model.
Antimicrob Agents Chemother;
62(12)2018 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30249700
20.
Effect of Linezolid plus Bedaquiline against Mycobacterium tuberculosis in Log Phase, Acid Phase, and Nonreplicating-Persister Phase in an In Vitro Assay.
Antimicrob Agents Chemother;
62(8)2018 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29866874