Detalhe da pesquisa
1.
Development of VER-50589 analogs as novel Hsp90 inhibitors.
Bioorg Med Chem Lett;
91: 129375, 2023 07 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37315698
2.
Design, synthesis and antitumor activity study of PARP-1/HDAC dual targeting inhibitors.
Bioorg Med Chem Lett;
71: 128821, 2022 09 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35643262
3.
Design, synthesis and antitumor activity study of a gemcitabine prodrug conjugated with a HDAC6 inhibitor.
Bioorg Med Chem Lett;
72: 128881, 2022 09 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35810950
4.
Design, synthesis and antitumor activity evaluation of novel HDAC inhibitors with tetrahydrobenzothiazole as the skeleton.
Bioorg Chem;
108: 104652, 2021 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33497873
5.
The design and synthesis of transient receptor potential vanilloid 3 inhibitors with novel skeleton.
Bioorg Chem;
114: 105115, 2021 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34175725
6.
Novel histone deacetylase inhibitors bearing a 4-piperidin-4-yl-triazole scaffold as antitumor agents.
Drug Dev Res;
81(1): 52-61, 2020 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31580523
7.
Aspergiolides A and B: Core Structural Establishment and Synthesis of Structural Analogues.
J Org Chem;
84(7): 4451-4457, 2019 04 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30865441
8.
Anti-tumor activity evaluation of novel tubulin and HDAC dual-targeting inhibitors.
Bioorg Med Chem Lett;
29(18): 2638-2645, 2019 09 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31400938
9.
Design of a fluorescent ligand targeting the S-adenosylmethionine binding site of the histone methyltransferase MLL1.
Org Biomol Chem;
14(2): 631-638, 2016 Jan 14.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26541578
10.
Integration of Bioorthogonal Probes and Q-FRET for the Detection of Histone Acetyltransferase Activity.
Chembiochem;
16(18): 2605-9, 2015 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26455821
11.
Eleganketal A, a highly oxygenated dibenzospiroketal from the marine-derived fungus Spicaria elegans KLA03.
J Nat Prod;
77(7): 1718-23, 2014 Jul 25.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24967847
12.
The Development of HDAC and Tubulin Dual-Targeting Inhibitors for Cancer Therapy.
Mini Rev Med Chem;
2023 Jul 17.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37461341
13.
Hybrid Histone Deacetylase Inhibitor: An Effective Strategy for Cancer Therapy.
Curr Med Chem;
30(20): 2267-2311, 2023.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36043742
14.
Cytotoxic metabolites from the antarctic psychrophilic fungus Oidiodendron truncatum.
J Nat Prod;
75(5): 920-7, 2012 May 25.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22583079
15.
WRQ-2, a gemcitabine prodrug, reverses gemcitabine resistance caused by hENT1 inhibition.
Drug Discov Ther;
16(6): 286-292, 2022 Dec 26.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36529509
16.
Cost-effectiveness of fuzuloparib compared to routine surveillance, niraparib and olaparib for maintenance treatment of patients with germline BRCA1/2 mutation and platinum-sensitive recurrent ovarian carcinoma in China.
Front Pharmacol;
13: 987337, 2022.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36686677
17.
Synthesis and activity evaluation of a new bestatin derivative LYP2 as an aminopeptidase N inhibitor.
Anticancer Drugs;
22(1): 99-103, 2011 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21048494
18.
Small Molecular Gemcitabine Prodrugs for Cancer Therapy.
Curr Med Chem;
27(33): 5562-5582, 2020.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31419928
19.
Drugs for the Treatment of Zika Virus Infection.
J Med Chem;
63(2): 470-489, 2020 01 23.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31549836
20.
Novel HDAC6 selective inhibitors with 4-aminopiperidine-1- carboxamide as the core structure enhanced growth inhibitory activity of bortezomib in MCF-7 cells.
Biosci Trends;
13(1): 91-97, 2019.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30867374