Detalhe da pesquisa
1.
A multi-cohort genome-wide association study in African ancestry individuals reveals risk loci for primary open-angle glaucoma.
Cell;
187(2): 464-480.e10, 2024 01 18.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38242088
2.
Evidence of epistasis in regions of long-range linkage disequilibrium across five complex diseases in the UK Biobank and eMERGE datasets.
Am J Hum Genet;
110(4): 575-591, 2023 04 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37028392
3.
Impact of natural selection on global patterns of genetic variation and association with clinical phenotypes at genes involved in SARS-CoV-2 infection.
Proc Natl Acad Sci U S A;
119(21): e2123000119, 2022 05 24.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35580180
4.
Mendelian pathway analysis of laboratory traits reveals distinct roles for ciliary subcompartments in common disease pathogenesis.
Am J Hum Genet;
108(3): 482-501, 2021 03 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33636100
5.
Novel EDGE encoding method enhances ability to identify genetic interactions.
PLoS Genet;
17(6): e1009534, 2021 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34086673
6.
Targeting the coronavirus nucleocapsid protein through GSK-3 inhibition.
Proc Natl Acad Sci U S A;
118(42)2021 10 19.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34593624
7.
Development of complemented comprehensive networks for rapid screening of repurposable drugs applicable to new emerging disease outbreaks.
J Transl Med;
21(1): 415, 2023 06 26.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37365631
8.
PheWAS and Beyond: The Landscape of Associations with Medical Diagnoses and Clinical Measures across 38,662 Individuals from Geisinger.
Am J Hum Genet;
102(4): 592-608, 2018 04 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29606303
9.
Epistatic Gene-Based Interaction Analyses for Glaucoma in eMERGE and NEIGHBOR Consortium.
PLoS Genet;
12(9): e1006186, 2016 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27623284
10.
A simulation study investigating power estimates in phenome-wide association studies.
BMC Bioinformatics;
19(1): 120, 2018 04 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29618318
11.
Biology-Driven Gene-Gene Interaction Analysis of Age-Related Cataract in the eMERGE Network.
Genet Epidemiol;
39(5): 376-84, 2015 Jul.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25982363
12.
Polygenic risk scores for cardiometabolic traits demonstrate importance of ancestry for predictive precision medicine.
Pac Symp Biocomput;
29: 611-626, 2024.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38160310
13.
DETECT: Feature extraction method for disease trajectory modeling in electronic health records.
AMIA Jt Summits Transl Sci Proc;
2023: 487-496, 2023.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37350926
14.
Inference of Causal Relationships Between Genetic Risk Factors for Cardiometabolic Phenotypes and Female-Specific Health Conditions.
J Am Heart Assoc;
12(5): e026561, 2023 03 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36846987
15.
The Penn Medicine BioBank: Towards a Genomics-Enabled Learning Healthcare System to Accelerate Precision Medicine in a Diverse Population.
J Pers Med;
12(12)2022 Nov 29.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36556195
16.
Quality Control Procedures for Genome-Wide Association Studies.
Curr Protoc;
2(11): e603, 2022 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36441943
17.
Exome-wide association analysis of CT imaging-derived hepatic fat in a medical biobank.
Cell Rep Med;
3(12): 100855, 2022 12 20.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36513072
18.
Large-scale genomic analyses reveal insights into pleiotropy across circulatory system diseases and nervous system disorders.
Nat Commun;
13(1): 3428, 2022 06 14.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35701404
19.
eQTpLot: a user-friendly R package for the visualization of colocalization between eQTL and GWAS signals.
BioData Min;
14(1): 32, 2021 Jul 17.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34273980
20.
A unified framework identifies new links between plasma lipids and diseases from electronic medical records across large-scale cohorts.
Nat Genet;
53(7): 972-981, 2021 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34140684