Detalhe da pesquisa
1.
Riboflavin protects against pancreatic cancer metastasis by targeting TGF-ß receptor 1.
Bioorg Chem;
146: 107274, 2024 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38503026
2.
Design and synthesis of dual cathepsin L and S inhibitors and antimetastatic activity evaluation in pancreatic cancer cells.
Bioorg Med Chem Lett;
80: 129087, 2023 01 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36427655
3.
Novel pyrrolo[2,1-c][1,4]benzodiazepine-3,11-dione (PBD) derivatives as selective HDAC6 inhibitors to suppress tumor metastasis and invasion in vitro and in vivo.
Bioorg Chem;
114: 105081, 2021 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34153811
4.
Discovery of a novel and selective cathepsin L inhibitor with anti-metastatic ability in vitro and in vivo against breast cancer cells.
Bioorg Chem;
115: 105256, 2021 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34426153
5.
Discovery of specific HDAC6 inhibitor with anti-metastatic effects in pancreatic cancer cells through virtual screening and biological evaluation.
Bioorg Chem;
97: 103679, 2020 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32120077
6.
A novel cathepsin L inhibitor prevents the progression of idiopathic pulmonary fibrosis.
Bioorg Chem;
94: 103417, 2020 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31744600
7.
Discovery of a novel cathepsin inhibitor with dual autophagy-inducing and metastasis-inhibiting effects on breast cancer cells.
Bioorg Chem;
84: 239-253, 2019 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30503850
8.
Salvianolic acid B inhibits myofibroblast transdifferentiation in experimental pulmonary fibrosis via the up-regulation of Nrf2.
Biochem Biophys Res Commun;
495(1): 325-331, 2018 01 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29108993
9.
Discovery of novel cathepsin inhibitors with potent anti-metastatic effects in breast cancer cells.
Bioorg Chem;
81: 672-680, 2018 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30253340
10.
Anti-pulmonary fibrotic activity of salvianolic acid B was screened by a novel method based on the cyto-biophysical properties.
Biochem Biophys Res Commun;
468(1-2): 214-20, 2015.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26523510
11.
Caryophyllene sesquiterpenes from the marine-derived fungus Ascotricha sp. ZJ-M-5 by the one strain-many compounds strategy.
J Nat Prod;
77(6): 1367-71, 2014 Jun 27.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24878335
12.
Screening approach by a combination of computational and in vitro experiments: identification of fluvastatin sodium as a potential SIRT2 inhibitor.
J Mol Model;
30(6): 188, 2024 May 27.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38801625
13.
ß-Eudesmol induces JNK-dependent apoptosis through the mitochondrial pathway in HL60 cells.
Phytother Res;
27(3): 338-43, 2013 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22585533
14.
JNK-dependent Atg4 upregulation mediates asperphenamate derivative BBP-induced autophagy in MCF-7 cells.
Toxicol Appl Pharmacol;
263(1): 21-31, 2012 Aug 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22668848
15.
Synthesis and in vitro antitumor activity of asperphenamate derivatives as autophagy inducer.
Bioorg Med Chem Lett;
22(6): 2216-20, 2012 Mar 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22361137
16.
Isolation and cytotoxic activity of selaginellin derivatives and biflavonoids from Selaginella tamariscina.
Planta Med;
78(4): 390-2, 2012 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22271084
17.
Activation of ATM-Chk2 by 16-dehydropregnenolone induces G1 phase arrest and apoptosis in HeLa cells.
J Asian Nat Prod Res;
14(9): 817-25, 2012.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22694166
18.
ASPER-29 suppresses the metastasis of pancreatic cancer cells by dual inhibition of cathepsin-L and cathepsin-S.
Chem Biol Interact;
353: 109811, 2022 Feb 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35016848
19.
Structural and PK-guided identification of indole-based non-acidic autotaxin (ATX) inhibitors exhibiting high in vivo anti-fibrosis efficacy in rodent model.
Eur J Med Chem;
227: 113951, 2022 Jan 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34742015
20.
Human Glioma Cells Therapy Using ATRA-Induced Differentiation Method to Promote the Inhibitive Effect of TMZ and CCDP.
J Healthc Eng;
2021: 6717582, 2021.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34745507