Detalhe da pesquisa
1.
ERK/RSK-mediated phosphorylation of Y-box binding protein-1 aggravates diabetic cardiomyopathy by suppressing its interaction with deubiquitinase OTUB1.
J Biol Chem;
298(6): 101989, 2022 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35490780
2.
Podocyte Integrin-ß3 and Activated Protein C Coordinately Restrict RhoA Signaling and Ameliorate Diabetic Nephropathy.
J Am Soc Nephrol;
31(8): 1762-1780, 2020 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32709711
3.
Signal integration at the PI3K-p85-XBP1 hub endows coagulation protease activated protein C with insulin-like function.
Blood;
130(12): 1445-1455, 2017 09 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28687614
4.
Homeostatic nuclear RAGE-ATM interaction is essential for efficient DNA repair.
Nucleic Acids Res;
45(18): 10595-10613, 2017 Oct 13.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28977635
5.
Farnesoid X Receptor Agonism Protects against Diabetic Tubulopathy: Potential Add-On Therapy for Diabetic Nephropathy.
J Am Soc Nephrol;
28(11): 3182-3189, 2017 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28696246
6.
Caspase-1, but Not Caspase-3, Promotes Diabetic Nephropathy.
J Am Soc Nephrol;
27(8): 2270-5, 2016 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26832955
7.
Activated protein C ameliorates diabetic nephropathy by epigenetically inhibiting the redox enzyme p66Shc.
Proc Natl Acad Sci U S A;
110(2): 648-53, 2013 Jan 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23267072
8.
Activated Protein C Ameliorates Renal Ischemia-Reperfusion Injury by Restricting Y-Box Binding Protein-1 Ubiquitination.
J Am Soc Nephrol;
26(11): 2789-99, 2015 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26015455
9.
Nlrp3-inflammasome activation in non-myeloid-derived cells aggravates diabetic nephropathy.
Kidney Int;
87(1): 74-84, 2015 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25075770
10.
Cytoprotective signaling by activated protein C requires protease-activated receptor-3 in podocytes.
Blood;
119(3): 874-83, 2012 Jan 19.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22117049
11.
Activated protein C protects against diabetic nephropathy by inhibiting endothelial and podocyte apoptosis.
Nat Med;
13(11): 1349-58, 2007 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-17982464
12.
Nuclear factor erythroid-derived 2 (Nfe2) regulates JunD DNA-binding activity via acetylation: a novel mechanism regulating trophoblast differentiation.
J Biol Chem;
287(8): 5400-11, 2012 Feb 17.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22174410
13.
Low but sustained coagulation activation ameliorates glucose-induced podocyte apoptosis: protective effect of factor V Leiden in diabetic nephropathy.
Blood;
117(19): 5231-42, 2011 May 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21389321
14.
Human RAGE antibody protects against AGE-mediated podocyte dysfunction.
Nephrol Dial Transplant;
27(8): 3129-36, 2012 Aug.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22510380
15.
Regulation of the Homeostatic Unfolded Protein Response in Diabetic Nephropathy.
Pharmaceuticals (Basel);
15(4)2022 Mar 25.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35455399
16.
Pharmacologic IRE1α kinase inhibition alleviates aortic dissection by decreasing vascular smooth muscle cells apoptosis.
Int J Biol Sci;
18(3): 1053-1064, 2022.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35173538
17.
Chronic Obstructive Pulmonary Disease and the Cardiovascular System: Vascular Repair and Regeneration as a Therapeutic Target.
Front Cardiovasc Med;
8: 649512, 2021.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33912600
18.
Activated Protein C Ameliorates Diabetic Cardiomyopathy via Modulating OTUB1/YB-1/MEF2B Axis.
Front Cardiovasc Med;
8: 758158, 2021.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34778410
19.
The MEK inhibitor U0126 ameliorates diabetic cardiomyopathy by restricting XBP1's phosphorylation dependent SUMOylation.
Int J Biol Sci;
17(12): 2984-2999, 2021.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34421344
20.
Lipid presentation by the protein C receptor links coagulation with autoimmunity.
Science;
371(6534)2021 03 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33707237