Detalhe da pesquisa
1.
A small-molecule PI3Kα activator for cardioprotection and neuroregeneration.
Nature;
618(7963): 159-168, 2023 Jun.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37225977
2.
PI3K signaling through a biochemical systems lens.
J Biol Chem;
299(10): 105224, 2023 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37673340
3.
Positive correlation between transcriptomic stemness and PI3K/AKT/mTOR signaling scores in breast cancer, and a counterintuitive relationship with PIK3CA genotype.
PLoS Genet;
17(11): e1009876, 2021 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34762647
4.
Oncogenic PIK3CA promotes cellular stemness in an allele dose-dependent manner.
Proc Natl Acad Sci U S A;
116(17): 8380-8389, 2019 04 23.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30948643
5.
PI3K in stemness regulation: from development to cancer.
Biochem Soc Trans;
48(1): 301-315, 2020 02 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32010943
6.
Epigenetic Regulation of Vascular Smooth Muscle Cells by Histone H3 Lysine 9 Dimethylation Attenuates Target Gene-Induction by Inflammatory Signaling.
Arterioscler Thromb Vasc Biol;
39(11): 2289-2302, 2019 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31434493
7.
Multiomic profiling of breast cancer cells uncovers stress MAPK-associated sensitivity to AKT degradation.
Sci Signal;
17(825): eadf2670, 2024 Feb 27.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38412255
8.
Precision Targeting of Mutant PI3Kα in Cancer by Selective Degradation.
Cancer Discov;
12(1): 20-22, 2022 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35022207
9.
PIK3CA-related overgrowth: silver bullets from the cancer arsenal?
Trends Mol Med;
28(4): 255-257, 2022 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35272946
10.
NODAL/TGFß signalling mediates the self-sustained stemness induced by PIK3CAH1047R homozygosity in pluripotent stem cells.
Dis Model Mech;
14(3)2021 03 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33514588
11.
Cracking the context-specific PI3K signaling code.
Sci Signal;
13(613)2020 01 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31911433
12.
Scientific impact and the quest for visibility.
FEBS J;
286(20): 3968-3974, 2019 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31468701
13.
Luminescent peptide tagging enables efficient screening for CRISPR-mediated knock-in in human induced pluripotent stem cells.
Wellcome Open Res;
4: 37, 2019.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31363496
14.
Perspective: Potential Impact and Therapeutic Implications of Oncogenic PI3K Activation on Chromosomal Instability.
Biomolecules;
9(8)2019 08 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31374965
15.
Cancer-Associated PIK3CA Mutations in Overgrowth Disorders.
Trends Mol Med;
24(10): 856-870, 2018 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30197175