Outcomes of combined use of topical and intravenous tranexamic acid on surgical field quality during functional endoscopic sinus surgery: Randomized controlled trial.

BACKGROUND: Intraoperative bleeding during functional endoscopic sinus surgery (FESS) poses a challenge to both surgeon and anesthetist. The primary aim of this study was to evaluate the effectiveness of local, intravenous and combined use of tranexamic acid (TA) in improving the surgical field quality during FESS. METHODS: We conducted a randomized controlled double-blinded prospective trial on 120 patients scheduled for elective FESS. After induction of general anesthesia, patients were randomly and evenly assigned to one of four groups; IV TA, local TA, both IV and local TA, and placebo. Surgical field was assessed using five-point Boezaart scale. Total fentanyl and esmolol consumption, operative time, recovery time, and postoperative complications were recorded. RESULTS: Surgical field quality score was the best in IV and local TA group compared to others (p < 0.001). Mean operative time was found significantly shorter in IV and local TA group than placebo one. Total fentanyl consumption was significantly lower in IV and local TA group comparing to others (p = 0.025). Mean recovery time was significantly shorter for IV and local TA group compared to others. Total fentanyl consumption was significantly lower in IV and local TA group comparing to others. No significant differences were found of mean arterial pressure and heart rate decline in four groups. None of the patients in four groups required esmolol administration. No statistically significant differences were found in change of hemoglobin, hematocrit, prothrombin time, and partial thromboplastin time over time in all groups. CONCLUSION: The combined use of topical and intravenous TA provided the best surgical field in FESS, less fentanyl consumption, and less recovery time without causing significant side effects.

Minimally Invasive Technique for Correction of Prominent Ear.

OBJECTIVES: Prominent ear is not an uncommon deformity with 5% prevalence in population worldwide. Although there is no physiological handicap in this deformity, it affects the psychology and social integration, especially in children. Many surgical techniques are performed to correct this deformity. In this study, we illustrate a minimally invasive technique in cases of prominent ear and evaluate its efficacy. MATERIALS AND METHODS: A total of 16 patients were operated by incisionless otoplasty in both ears simultaneously. Therefore, 32 ears were included in the study. Postoperative follow-up was carried out for 6 months to determine the efficacy of this technique, complications, and recurrence of the abnormal shape. RESULTS: Two ears (2/32) were presented with slight protrusion three months postoperatively Three ears had postoperatively exposed sutures that needed to be embedded again under local anesthesia. The satisfaction rate was found to be 88% by the visual analog scale. No perichondritis or other complications occurred postoperatively. The technique results in correction of the deformity without any visible evidence of surgery. CONCLUSION: This technique is effective and safe for correction of prominent ear with negligible rate of complications and rapid recovery time.