Detalhe da pesquisa
1.
IL-15Rα membrane anchorage in either cis or trans is required for stabilization of IL-15 and optimal signaling.
J Cell Sci;
133(5)2019 12 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31653781
2.
Rational modification, synthesis and biological evaluation of N-substituted phthalazinone derivatives designed to target interleukine-15 protein.
Bioorg Med Chem;
39: 116161, 2021 06 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33932805
3.
Two-Chains Tissue Plasminogen Activator Unifies Met and NMDA Receptor Signalling to Control Neuronal Survival.
Int J Mol Sci;
22(24)2021 Dec 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34948279
4.
Multivalent Thiosialosides and Their Synergistic Interaction with Pathogenic Sialidases.
Chemistry;
25(9): 2358-2365, 2019 Feb 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30516296
5.
Cutting Edge: Differential Fine-Tuning of IL-2- and IL-15-Dependent Functions by Targeting Their Common IL-2/15Rß/γc Receptor.
J Immunol;
198(12): 4563-4568, 2017 06 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28507024
6.
A novel, smaller scaffold for Affitins: Showcase with binders specific for EpCAM.
Biotechnol Bioeng;
115(2): 290-299, 2018 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28976545
7.
Syndecan-1 regulates the biological activities of interleukin-34.
Biochim Biophys Acta;
1853(5): 1010-21, 2015 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25662098
8.
IL-34 and M-CSF form a novel heteromeric cytokine and regulate the M-CSF receptor activation and localization.
Cytokine;
76(2): 170-181, 2015 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26095744
9.
Tumor targeting of the IL-15 superagonist RLI by an anti-GD2 antibody strongly enhances its antitumor potency.
Int J Cancer;
133(3): 757-65, 2013 Aug 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23354868
10.
Counteracting Interleukin-15 to Elucidate Its Modes of Action in Physiology and Pathology.
J Interferon Cytokine Res;
43(1): 2-22, 2023 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36651845
11.
Selective Targeting of IL-15Rα Is Sufficient to Reduce Inflammation.
Front Immunol;
13: 886213, 2022.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35592318
12.
hnRNP-A1 binds to the IRES of MELOE-1 antigen to promote MELOE-1 translation in stressed melanoma cells.
Mol Oncol;
16(3): 594-606, 2022 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34418284
13.
Thrombolysis by PLAT/tPA increases serum free IGF1 leading to a decrease of deleterious autophagy following brain ischemia.
Autophagy;
18(6): 1297-1317, 2022 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34520334
14.
Definition and characterization of an inhibitor for interleukin-31.
J Biol Chem;
285(20): 14955-14963, 2010 May 14.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20335179
15.
Phosphorothioate-modified TLR9 ligands protect cancer cells against TRAIL-induced apoptosis.
J Immunol;
183(7): 4371-7, 2009 Oct 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19734228
16.
Factor VIII-von Willebrand factor complex inhibits osteoclastogenesis and controls cell survival.
J Biol Chem;
284(46): 31704-13, 2009 Nov 13.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19758994
17.
Discovery of a Small-Molecule Inhibitor of Interleukin 15: Pharmacophore-Based Virtual Screening and Hit Optimization.
J Med Chem;
60(14): 6249-6272, 2017 07 27.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28657314
18.
Affinity transfer to the archaeal extremophilic Sac7d protein by insertion of a CDR.
Protein Eng Des Sel;
27(10): 431-8, 2014 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25301962
19.
Switching an anti-IgG binding site between archaeal extremophilic proteins results in Affitins with enhanced pH stability.
J Biotechnol;
192 Pt A: 123-9, 2014 Dec 20.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25450641
20.
Highly potent anti-CD20-RLI immunocytokine targeting established human B lymphoma in SCID mouse.
MAbs;
6(4): 1026-37, 2014.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25072059