Detalhe da pesquisa
1.
Immune evasion, infectivity, and fusogenicity of SARS-CoV-2 BA.2.86 and FLip variants.
Cell;
187(3): 585-595.e6, 2024 Feb 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38194968
2.
Discovering selective antiferroptotic inhibitors of the 15LOX/PEBP1 complex noninterfering with biosynthesis of lipid mediators.
Proc Natl Acad Sci U S A;
120(25): e2218896120, 2023 Jun 20.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37327313
3.
FOXK2 targeting by the SCF-E3 ligase subunit FBXO24 for ubiquitin mediated degradation modulates mitochondrial respiration.
J Biol Chem;
: 107359, 2024 May 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38735474
4.
A combinatorial F box protein directed pathway controls TRAF adaptor stability to regulate inflammation.
Nat Immunol;
14(5): 470-9, 2013 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23542741
5.
F-box protein FBXL19-mediated ubiquitination and degradation of the receptor for IL-33 limits pulmonary inflammation.
Nat Immunol;
13(7): 651-8, 2012 Jun 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22660580
6.
ISGylation of NF-κBp65 by SCFFBXL19 E3 Ligase Diminishes Endothelial Inflammation.
Arterioscler Thromb Vasc Biol;
43(5): 674-683, 2023 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36994728
7.
Cross-Regulation of F-Box Protein FBXL2 with T-bet and TNF-α during Acute and Chronic Lung Allograft Rejection.
J Immunol;
209(9): 1788-1795, 2022 11 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36113884
8.
Strikingly High Activity of 15-Lipoxygenase Towards Di-Polyunsaturated Arachidonoyl/Adrenoyl-Phosphatidylethanolamines Generates Peroxidation Signals of Ferroptotic Cell Death.
Angew Chem Int Ed Engl;
63(9): e202314710, 2024 Feb 26.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38230815
9.
Inhibiting the Deubiquitinase UCHL1 Reduces SARS-CoV-2 Viral Uptake by ACE2.
Am J Respir Cell Mol Biol;
68(5): 566-576, 2023 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36730646
10.
The E3 ligase subunit FBXO45 binds the interferon-λ receptor and promotes its degradation during influenza virus infection.
J Biol Chem;
298(12): 102698, 2022 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36379255
11.
Influenza virus reduces ubiquitin E3 ligase MARCH10 expression to decrease ciliary beat frequency.
Am J Physiol Lung Cell Mol Physiol;
324(5): L666-L676, 2023 05 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36852930
12.
Serum metabolomic signatures of fatty acid oxidation defects differentiate host-response subphenotypes of acute respiratory distress syndrome.
Respir Res;
24(1): 136, 2023 May 20.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37210531
13.
A Fbxo48 inhibitor prevents pAMPKα degradation and ameliorates insulin resistance.
Nat Chem Biol;
17(3): 298-306, 2021 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33495648
14.
Redox lipid reprogramming commands susceptibility of macrophages and microglia to ferroptotic death.
Nat Chem Biol;
16(3): 278-290, 2020 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32080625
15.
Pathogenesis of pneumonia and acute lung injury.
Clin Sci (Lond);
136(10): 747-769, 2022 05 27.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35621124
16.
SCF FBXW17 E3 ubiquitin ligase regulates FBXL19 stability and cell migration.
J Cell Biochem;
122(3-4): 326-334, 2021 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33053230
17.
Increased Alternative Complement Pathway Function and Improved Survival during Critical Illness.
Am J Respir Crit Care Med;
202(2): 230-240, 2020 07 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32374177
18.
Toll-like Receptor 8 Stability Is Regulated by Ring Finger 216 in Response to Circulating MicroRNAs.
Am J Respir Cell Mol Biol;
62(2): 157-167, 2020 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31385713
19.
Neutralization of the SARS-CoV-2 Omicron BA.4/5 and BA.2.12.1 Subvariants.
N Engl J Med;
386(26): 2526-2528, 2022 06 30.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35704428
20.
Neutralization of the SARS-CoV-2 Deltacron and BA.3 Variants.
N Engl J Med;
386(24): 2340-2342, 2022 06 16.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35584183