Detalhe da pesquisa
1.
SIRT6 Is Responsible for More Efficient DNA Double-Strand Break Repair in Long-Lived Species.
Cell;
177(3): 622-638.e22, 2019 04 18.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31002797
2.
Cytoplasmic PARP1 links the genome instability to the inhibition of antiviral immunity through PARylating cGAS.
Mol Cell;
82(11): 2032-2049.e7, 2022 06 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35460603
3.
SIRT2 promotes base excision repair by transcriptionally activating OGG1 in an ATM/ATR-dependent manner.
Nucleic Acids Res;
52(9): 5107-5120, 2024 May 22.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38554113
4.
Impaired end joining induces cardiac atrophy in a Hutchinson-Gilford progeria mouse model.
Proc Natl Acad Sci U S A;
120(47): e2309200120, 2023 Nov 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37967221
5.
Androgen signaling stabilizes genomes to counteract senescence by promoting XRCC4 transcription.
EMBO Rep;
24(12): e56984, 2023 Dec 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37955230
6.
Nuclear cGAS suppresses DNA repair and promotes tumorigenesis.
Nature;
563(7729): 131-136, 2018 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30356214
7.
DNA polymerase η promotes nonhomologous end joining upon etoposide exposure dependent on the scaffolding protein Kap1.
J Biol Chem;
298(5): 101861, 2022 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35339488
8.
Sirt1 Protects Subventricular Zone-Derived Neural Stem Cells from DNA Double-Strand Breaks and Contributes to Olfactory Function Maintenance in Aging Mice.
Stem Cells;
40(5): 493-507, 2022 05 27.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35349711
9.
Rational combination therapy for hepatocellular carcinoma with PARP1 and DNA-PK inhibitors.
Proc Natl Acad Sci U S A;
117(42): 26356-26365, 2020 10 20.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33020270
10.
Preclinical validation and phase I trial of 4-hydroxysalicylanilide, targeting ribonucleotide reductase mediated dNTP synthesis in multiple myeloma.
J Biomed Sci;
29(1): 32, 2022 May 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35546402
11.
The deacetylase SIRT6 promotes the repair of UV-induced DNA damage by targeting DDB2.
Nucleic Acids Res;
48(16): 9181-9194, 2020 09 18.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32789493
12.
DNA double-strand break repair and nucleic acid-related immunity.
Acta Biochim Biophys Sin (Shanghai);
54(6): 828-835, 2022 May 25.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35975605
13.
An HMGA2-p62-ERα axis regulates uterine leiomyomas proliferation.
FASEB J;
34(8): 10966-10983, 2020 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32592217
14.
A PARP1-BRG1-SIRT1 axis promotes HR repair by reducing nucleosome density at DNA damage sites.
Nucleic Acids Res;
47(16): 8563-8580, 2019 09 19.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31291457
15.
Histone H3K27 methylation modulates the dynamics of FANCD2 on chromatin to facilitate NHEJ and genome stability.
J Cell Sci;
131(12)2018 06 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29760279
16.
Identification of a cellularly active SIRT6 allosteric activator.
Nat Chem Biol;
14(12): 1118-1126, 2018 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30374165
17.
High-molecular-mass hyaluronan mediates the cancer resistance of the naked mole rat.
Nature;
499(7458): 346-9, 2013 Jul 18.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23783513
18.
Reply to: Binding site for MDL-801 on SIRT6.
Nat Chem Biol;
17(5): 522-523, 2021 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33649600
19.
Knock-in reporter mice demonstrate that DNA repair by non-homologous end joining declines with age.
PLoS Genet;
10(7): e1004511, 2014 Jul.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25033455
20.
Insights into the discrepant luminescence for BaSiO3 :Eu2+ phosphors prepared by solid-state reaction and precipitation reaction methods.
Luminescence;
32(6): 957-963, 2017 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28220634