Detalhe da pesquisa
1.
XIST loss impairs mammary stem cell differentiation and increases tumorigenicity through Mediator hyperactivation.
Cell;
185(12): 2164-2183.e25, 2022 06 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35597241
2.
Regulation of transcription through acetylation of H3K122 on the lateral surface of the histone octamer.
Cell;
152(4): 859-72, 2013 Feb 14.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23415232
3.
Prdm3 and Prdm16 are H3K9me1 methyltransferases required for mammalian heterochromatin integrity.
Cell;
150(5): 948-60, 2012 Aug 31.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22939622
4.
H2A.Z facilitates licensing and activation of early replication origins.
Nature;
577(7791): 576-581, 2020 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31875854
5.
Author Correction: H2A.Z facilitates licensing and activation of early replication origins.
Nature;
578(7793): E8, 2020 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31932733
6.
A Family of Vertebrate-Specific Polycombs Encoded by the LCOR/LCORL Genes Balance PRC2 Subtype Activities.
Mol Cell;
70(3): 408-421.e8, 2018 05 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29628311
7.
A meiotic XPF-ERCC1-like complex recognizes joint molecule recombination intermediates to promote crossover formation.
Genes Dev;
32(3-4): 283-296, 2018 02 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29440262
8.
Functional characterization of 5p15.33 risk locus in uveal melanoma reveals rs452384 as a functional variant and NKX2.4 as an allele-specific interactor.
Am J Hum Genet;
109(12): 2196-2209, 2022 12 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36459980
9.
Identification of potential common genetic modifiers of neurofibromas: a genome-wide association study in 1333 patients with neurofibromatosis type 1.
Br J Dermatol;
190(2): 226-243, 2024 Jan 23.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37831592
10.
Succinylation of H3K122 destabilizes nucleosomes and enhances transcription.
EMBO Rep;
22(3): e51009, 2021 03 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33512761
11.
Jarid2 Methylation via the PRC2 Complex Regulates H3K27me3 Deposition during Cell Differentiation.
Mol Cell;
57(5): 769-783, 2015 Mar 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25620564
12.
Impaired PRC2 activity promotes transcriptional instability and favors breast tumorigenesis.
Genes Dev;
29(24): 2547-62, 2015 Dec 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26637281
13.
The histone H3 lysine 9 methyltransferases G9a and GLP regulate polycomb repressive complex 2-mediated gene silencing.
Mol Cell;
53(2): 277-89, 2014 Jan 23.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24389103
14.
Jarid2 Is Implicated in the Initial Xist-Induced Targeting of PRC2 to the Inactive X Chromosome.
Mol Cell;
53(2): 301-16, 2014 Jan 23.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24462204
15.
EZH1/2 function mostly within canonical PRC2 and exhibit proliferation-dependent redundancy that shapes mutational signatures in cancer.
Proc Natl Acad Sci U S A;
116(13): 6075-6080, 2019 03 26.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30867289
16.
Mechanisms Regulating PRC2 Recruitment and Enzymatic Activity.
Trends Biochem Sci;
42(7): 531-542, 2017 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28483375
17.
PRC2 is dispensable for HOTAIR-mediated transcriptional repression.
EMBO J;
36(8): 981-994, 2017 04 13.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28167697
18.
Nucleosome-binding activities within JARID2 and EZH1 regulate the function of PRC2 on chromatin.
Genes Dev;
27(24): 2663-77, 2013 Dec 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24352422
19.
EZH2 couples pancreatic regeneration to neoplastic progression.
Genes Dev;
26(5): 439-44, 2012 Mar 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22391448
20.
Histone variants H2A.Z and H3.3 coordinately regulate PRC2-dependent H3K27me3 deposition and gene expression regulation in mES cells.
BMC Biol;
16(1): 107, 2018 09 24.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30249243