Detalhe da pesquisa
1.
Efficacy and safety of subcutaneous spesolimab for the prevention of generalised pustular psoriasis flares (Effisayil 2): an international, multicentre, randomised, placebo-controlled trial.
Lancet;
402(10412): 1541-1551, 2023 10 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37738999
2.
Trial of Spesolimab for Generalized Pustular Psoriasis.
N Engl J Med;
385(26): 2431-2440, 2021 12 23.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34936739
3.
Generalized pustular psoriasis: A global Delphi consensus on clinical course, diagnosis, treatment goals and disease management.
J Eur Acad Dermatol Venereol;
37(4): 737-752, 2023 Apr.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36606566
4.
Pustular psoriasis of pregnancy: Clinical and genetic characteristics in a series of eight patients and review of the literature.
Dermatol Ther;
35(8): e15593, 2022 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35598320
5.
Mutations in SULT2B1 Cause Autosomal-Recessive Congenital Ichthyosis in Humans.
Am J Hum Genet;
100(6): 926-939, 2017 Jun 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28575648
6.
Genetical, clinical, and functional analysis of a large international cohort of patients with autosomal recessive congenital ichthyosis due to mutations in NIPAL4.
Hum Mutat;
40(12): 2318-2333, 2019 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31347739
7.
The Generalized Pustular Psoriasis Physician Global Assessment (GPPGA) score: online assessment and validation study of a specific measure of GPP disease activity.
Br J Dermatol;
189(1): 138-140, 2023 07 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37075220
8.
Inhibition of the Interleukin-36 Pathway for the Treatment of Generalized Pustular Psoriasis.
N Engl J Med;
380(10): 981-983, 2019 03 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30855749
9.
Mutations in CERS3 cause autosomal recessive congenital ichthyosis in humans.
PLoS Genet;
9(6): e1003536, 2013 Jun.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23754960
10.
Interleukin-36-receptor antagonist deficiency and generalized pustular psoriasis.
N Engl J Med;
365(7): 620-8, 2011 Aug 18.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21848462
11.
Erythrokeratodermia Variabilis-like Phenotype in Patients Carrying ABCA12 Mutations.
Genes (Basel);
15(3)2024 Feb 24.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38540347
12.
International Consensus Definition and Diagnostic Criteria for Generalized Pustular Psoriasis From the International Psoriasis Council.
JAMA Dermatol;
2024 May 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38691347
13.
Congenital lamellar ichthyosis in Tunisia is caused by a founder nonsense mutation in the TGM1 gene.
Mol Biol Rep;
40(3): 2527-32, 2013 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23192619
14.
Design of Effisayil™ 2: A Randomized, Double-Blind, Placebo-Controlled Study of Spesolimab in Preventing Flares in Patients with Generalized Pustular Psoriasis.
Dermatol Ther (Heidelb);
13(1): 347-359, 2023 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36333618
15.
Pathophysiology of Generalized Pustular Psoriasis.
Am J Clin Dermatol;
23(Suppl 1): 13-19, 2022 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35061228
16.
Great imitator with exclusive oral manifestations.
Clin Case Rep;
10(3): e05569, 2022 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35356175
17.
Clinical and genetic investigation of ichthyosis in familial and sporadic cases in south of Tunisia: genotype-phenotype correlation.
BMC Med Genomics;
15(1): 4, 2022 01 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34983512
18.
Hydroxychloroquine-induced acute generalized exanthematous pustulosis: a series of seven patients and review of the literature.
Int J Dermatol;
60(6): 742-748, 2021 Jun.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33598928
19.
Study protocol of the global Effisayil 1 Phase II, multicentre, randomised, double-blind, placebo-controlled trial of spesolimab in patients with generalized pustular psoriasis presenting with an acute flare.
BMJ Open;
11(3): e043666, 2021 03 30.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33785490
20.
Identification of a novel missense mutation in NIPAL4 gene: First 3D model construction predicted its pathogenicity.
Mol Genet Genomic Med;
8(3): e1104, 2020 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31876100