Detalhe da pesquisa
1.
Tubular Epithelial Cell HMGB1 Promotes AKI-CKD Transition by Sensitizing Cycling Tubular Cells to Oxidative Stress: A Rationale for Targeting HMGB1 during AKI Recovery.
J Am Soc Nephrol;
34(3): 394-411, 2023 03 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36857499
2.
Targeting the Alternative Vitamin E Metabolite Binding Site Enables Noncanonical PPARγ Modulation.
J Am Chem Soc;
145(27): 14802-14810, 2023 07 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37385602
3.
Fragment-based discovery of orphan nuclear receptor Nur77/NGFI-B ligands.
Bioorg Chem;
129: 106164, 2022 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36162288
4.
Electric cell-substrate impedance sensing in kidney research.
Nephrol Dial Transplant;
36(2): 216-223, 2021 01 25.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31598727
5.
The Kidney Contains Ontogenetically Distinct Dendritic Cell and Macrophage Subtypes throughout Development That Differ in Their Inflammatory Properties.
J Am Soc Nephrol;
31(2): 257-278, 2020 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31932472
6.
Mitochondria Permeability Transition versus Necroptosis in Oxalate-Induced AKI.
J Am Soc Nephrol;
30(10): 1857-1869, 2019 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31296606
7.
Dipeptidyl peptidase-4 inhibitor teneligliptin accelerates recovery from cisplatin-induced acute kidney injury by attenuating inflammation and promoting tubular regeneration.
Nephrol Dial Transplant;
34(10): 1669-1680, 2019 10 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30624740
8.
Extracellular traps in kidney disease.
Kidney Int;
94(6): 1087-1098, 2018 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30466565
9.
The macrophage phenotype and inflammasome component NLRP3 contributes to nephrocalcinosis-related chronic kidney disease independent from IL-1-mediated tissue injury.
Kidney Int;
93(3): 656-669, 2018 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29241624
10.
Intestinal Dysbiosis, Barrier Dysfunction, and Bacterial Translocation Account for CKD-Related Systemic Inflammation.
J Am Soc Nephrol;
28(1): 76-83, 2017 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27151924
11.
Hyperoxaluria Requires TNF Receptors to Initiate Crystal Adhesion and Kidney Stone Disease.
J Am Soc Nephrol;
28(3): 761-768, 2017 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27612997
12.
Oxalate-induced chronic kidney disease with its uremic and cardiovascular complications in C57BL/6 mice.
Am J Physiol Renal Physiol;
310(8): F785-F795, 2016 04 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26764204
13.
Glomerular parietal epithelial cell activation induces collagen secretion and thickening of Bowman's capsule in diabetes.
Lab Invest;
95(3): 273-82, 2015 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25531564
14.
Chemogenomics for NR1 nuclear hormone receptors.
Nat Commun;
15(1): 5201, 2024 Jun 18.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38890295
15.
Structure-Guided Design of a Highly Potent Partial RXR Agonist with Superior Physicochemical Properties.
J Med Chem;
67(3): 2152-2164, 2024 Feb 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38237049
16.
A "Kidney-on-the-Chip" Model Composed of Primary Human Tubular, Endothelial, and White Blood Cells.
Methods Mol Biol;
2664: 107-121, 2023.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37423985
17.
De Novo Design of Nurr1 Agonists via Fragment-Augmented Generative Deep Learning in Low-Data Regime.
J Med Chem;
66(12): 8170-8177, 2023 06 22.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37256819
18.
Structural Modification of the Natural Product Valerenic Acid Tunes RXR Homodimer Agonism.
ChemMedChem;
18(21): e202300404, 2023 11 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37697963
19.
Rational Design of a New RXR Agonist Scaffold Enabling Single-Subtype Preference for RXRα, RXRß, and RXRγ.
J Med Chem;
66(1): 333-344, 2023 01 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36533416
20.
Development of a Potent Nurr1 Agonist Tool for In Vivo Applications.
J Med Chem;
66(9): 6391-6402, 2023 05 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37127285