Detalhe da pesquisa
1.
A phase 1 pooled PK/PD analysis of bone resorption biomarkers for odanacatib, a Cathepsin K inhibitor.
J Pharmacokinet Pharmacodyn;
47(5): 473-484, 2020 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32647957
2.
Pharmacokinetic Interactions between the Hepatitis C Virus Inhibitors Elbasvir and Grazoprevir and HIV Protease Inhibitors Ritonavir, Atazanavir, Lopinavir, and Darunavir in Healthy Volunteers.
Antimicrob Agents Chemother;
63(4)2019 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30745392
3.
Effect of tildrakizumab (MK-3222), a high affinity, selective anti-IL23p19 monoclonal antibody, on cytochrome P450 metabolism in subjects with moderate to severe psoriasis.
Br J Clin Pharmacol;
84(10): 2292-2302, 2018 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29926968
4.
Population pharmacokinetics of molnupiravir in adults with COVID-19: Lack of clinically important exposure variation across individuals.
CPT Pharmacometrics Syst Pharmacol;
12(12): 1859-1871, 2023 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37798914
5.
Single-dose phase I study to evaluate the pharmacokinetics of posaconazole in new tablet and capsule formulations relative to oral suspension.
Antimicrob Agents Chemother;
56(8): 4196-201, 2012 Aug.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22615291
6.
Vorapaxar, an oral PAR-1 receptor antagonist, does not affect the pharmacokinetics and pharmacodynamics of warfarin.
Eur J Clin Pharmacol;
68(11): 1509-16, 2012 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22476387
7.
Phase 1b/3 Pharmacokinetics and Safety Study of Intravenous Posaconazole in Adult Asian Participants at High Risk for Invasive Fungal Infections.
Adv Ther;
39(4): 1697-1710, 2022 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35167031
8.
Determination of posaconazole levels in toenails of adults with onychomycosis following oral treatment with four regimens of posaconazole for 12 or 24 weeks.
Antimicrob Agents Chemother;
55(9): 4424-6, 2011 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21746944
9.
Skin concentrations and pharmacokinetics of posaconazole after oral administration.
Antimicrob Agents Chemother;
54(5): 1807-10, 2010 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20194702
10.
Effects of oral posaconazole on the pharmacokinetic properties of oral and intravenous midazolam: a phase I, randomized, open-label, crossover study in healthy volunteers.
Clin Ther;
31(2): 286-98, 2009 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19302901
11.
Pharmacokinetic Interactions Between the Fixed-Dose Combinations of Elvitegravir/Cobicistat/Tenofovir Disoproxil Fumarate/Emtricitabine and Elbasvir/Grazoprevir in Healthy Adult Participants.
Clin Pharmacol Drug Dev;
8(7): 952-961, 2019 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31173673
12.
Assessment of Drug Interaction Potential Between the Hepatitis C Virus Direct-Acting Antiviral Agents Elbasvir/Grazoprevir and the Nucleotide Analog Reverse-Transcriptase Inhibitor Tenofovir Disoproxil Fumarate.
Clin Pharmacol Drug Dev;
8(7): 962-970, 2019 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31173674
13.
Pharmacokinetics of oral posaconazole in neutropenic patients receiving chemotherapy for acute myelogenous leukemia or myelodysplastic syndrome.
Pharmacotherapy;
28(10): 1223-32, 2008 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-18823218
14.
No Pharmacokinetic Interactions Between Elbasvir or Grazoprevir and Methadone in Participants Receiving Maintenance Opioid Agonist Therapy.
Clin Transl Sci;
11(6): 553-561, 2018 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30040872
15.
No Pharmacokinetic Interactions Between Elbasvir or Grazoprevir and Buprenorphine/Naloxone in Healthy Participants and Participants Receiving Stable Opioid Agonist Therapy.
Clin Transl Sci;
11(6): 562-572, 2018 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30040871
16.
Pharmacokinetics of oral posaconazole in allogeneic hematopoietic stem cell transplant recipients with graft-versus-host disease.
Pharmacotherapy;
27(12): 1627-36, 2007 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-18041883
17.
Effect of oral posaconazole on the pharmacokinetics of cyclosporine and tacrolimus.
Pharmacotherapy;
27(6): 825-34, 2007 Jun.
Artigo
em Inglês
| MEDLINE
| ID: mdl-17542765
18.
The Absence of a Clinically Significant Effect of Food on the Single Dose Pharmacokinetics of Vorapaxar, a PAR-1 Antagonist, in Healthy Adult Subjects.
Clin Pharmacol Drug Dev;
2(4): 310-5, 2013 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27121935
19.
Effect of posaconazole on the pharmacokinetics of simvastatin and midazolam in healthy volunteers.
Expert Opin Drug Metab Toxicol;
8(1): 1-10, 2012 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22176629
20.
Effects of oral posaconazole on the pharmacokinetics of sirolimus.
Curr Med Res Opin;
25(3): 701-7, 2009 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19196220