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1.
Alcohol Clin Exp Res ; 40(3): 623-30, 2016 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-26895603

RESUMO

BACKGROUND: Recent evidence from alcohol and trauma studies suggests that disasters are associated with increases in the consumption of alcohol. The Great East Japan Earthquake and the associated nuclear disaster have continued to affect the mental health of evacuees from Fukushima. This study aimed to extend these findings by examining the relationship between drinking behaviors and the risk of mental illness after the compound disaster. METHODS: We conducted the Mental Health and Lifestyle Survey with 56,543 evacuees. Kessler's K6 was used to assess the risk of mental illness, and logistic regression models were applied to analyze how drinking behavior patterns influence the risk of serious mental illness after adjustment for confounding variables. RESULTS: Logistic regression analysis evidenced that beginning heavy and light drinkers had the highest and a higher risk of serious mental illness, respectively. Individuals who were nondrinkers pre- and postdisaster had the lowest proportional risk of mental illness. Abstainers also had some risk to their mental health after the compound disaster. CONCLUSIONS: The results of this study highlight that beginning drinkers have a high risk of serious mental illness. Thus, mental health professionals should pay attention to the drinking behaviors of evacuees, which might predict increased risk of serious mental illness and consequently indicate a need for psychological intervention.


Assuntos
Consumo de Bebidas Alcoólicas/epidemiologia , Consumo de Bebidas Alcoólicas/tendências , Terremotos , Acidente Nuclear de Fukushima , Inquéritos Epidemiológicos/métodos , Transtornos Mentais/epidemiologia , Adulto , Idoso , Consumo de Bebidas Alcoólicas/psicologia , Estudos Transversais , Feminino , Humanos , Japão/epidemiologia , Masculino , Transtornos Mentais/diagnóstico , Transtornos Mentais/psicologia , Pessoa de Meia-Idade , Estresse Psicológico/diagnóstico , Estresse Psicológico/epidemiologia , Estresse Psicológico/psicologia , Adulto Jovem
2.
Bull World Health Organ ; 93(9): 598-605, 2015 Sep 01.
Artigo em Inglês | MEDLINE | ID: mdl-26478623

RESUMO

OBJECTIVE: To assess relationships between the perception of radiation risks and psychological distress among evacuees from the Fukushima nuclear power plant disaster. METHODS: We analysed cross-sectional data from a survey of evacuees conducted in 2012. Psychological distress was classified as present or absent based on the K6 scale. Respondents recorded their views about the health risks of exposure to ionizing radiation, including immediate, delayed and genetic (inherited) health effects, on a four-point Likert scale. We examined associations between psychological distress and risk perception in logistic regression models. Age, gender, educational attainment, history of mental illness and the consequences of the disaster for employment and living conditions were potential confounders. FINDINGS: Out of the 180,604 people who received the questionnaire, we included 59,807 responses in our sample. There were 8717 respondents reporting psychological distress. Respondents who believed that radiation exposure was very likely to cause health effects were significantly more likely to be psychologically distressed than other respondents: odds ratio (OR) 1.64 (99.9% confidence interval, CI: 1.42-1.89) for immediate effects; OR: 1.48 (99.9% CI: 1.32-1.67) for delayed effects and OR: 2.17 (99.9% CI: 1.94-2.42) for genetic (inherited) effects. Similar results were obtained after controlling for individual characteristics and disaster-related stressors. CONCLUSION: Among evacuees of the Fukushima nuclear disaster, concern about radiation risks was associated with psychological distress.


Assuntos
Acidente Nuclear de Fukushima , Inquéritos Epidemiológicos , Exposição à Radiação , Estresse Psicológico , Adolescente , Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Risco , Adulto Jovem
3.
J Clin Psychopharmacol ; 35(3): 304-7, 2015 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-25839338

RESUMO

Extrapyramidal symptoms (EPS) are common adverse effects of antipsychotic treatment. This study examined the effects of the traditional Japanese herbal medicine (kampo) shakuyaku-kanzo-to on EPS during antipsychotic treatment. Twenty-two Japanese patients with psychiatric disorders who had developed EPS during antipsychotic treatment were randomly allocated to receive either shakuyaku-kanzo-to (7.5 g/d) or biperiden (3 mg/d) for 2 weeks. Extrapyramidal symptoms were evaluated using the Drug-Induced Extrapyramidal Symptom Scale (DIEPSS) and the Barnes Akathisia Rating Scale. Plasma levels of the monoamine metabolite homovanillic acid and serum prolactin levels were measured to investigate the mechanisms of action of shakuyaku-kanzo-to. Twenty of the 22 patients completed the study (10 patients in the shakuyaku-kanzo-to group and 10 patients in the biperiden group). There was a time effect on the Drug-Induced Extrapyramidal Symptom Scale total score (P < 0.01), suggesting that both shakuyaku-kanzo-to and biperiden decreased EPS. Notably, there was a time × drug interaction in dystonia, suggesting that shakuyaku-kanzo-to had a greater effect on dystonia compared with biperiden. No significant changes were observed in plasma homovanillic acid or serum prolactin levels after 2 weeks of treatment in either group. The effects of shakuyaku-kanzo-to on abnormal muscle tonus and dopamine D2 receptors may have contributed to improve EPS. These results suggest that shakuyaku-kanzo-to may be useful in decreasing EPS, especially dystonia, in patients undergoing treatment with antipsychotic agents.


Assuntos
Antipsicóticos/efeitos adversos , Doenças dos Gânglios da Base/induzido quimicamente , Medicamentos de Ervas Chinesas/uso terapêutico , Medicina Kampo/métodos , Adulto , Idoso , Idoso de 80 Anos ou mais , Antiparkinsonianos/uso terapêutico , Doenças dos Gânglios da Base/tratamento farmacológico , Biperideno/uso terapêutico , Combinação de Medicamentos , Feminino , Glycyrrhiza , Ácido Homovanílico/sangue , Humanos , Masculino , Pessoa de Meia-Idade , Paeonia , Prolactina/sangue , Adulto Jovem
4.
J Orthop Sci ; 20(3): 469-74, 2015 May.
Artigo em Inglês | MEDLINE | ID: mdl-25727356

RESUMO

BACKGROUND: We developed the Brief Scale for Psychiatric Problems in Orthopaedic Patients (BS-POP, physician and patient versions) and have previously shown that the BS-POP is reliable and has construct validity, criterion validity, and reproducibility. The present study aimed to proactively verify the responsiveness of the BS-POP with regard to chronic low back pain (LBP) patients. METHODS: The study subjects included 193 chronic LBP patients (81 males, 112 females; mean age 62 years) who had suffered from persistent LBP for ≥3 months. During the first test (before the treatment), the BS-POP, the Minnesota Multiphasic Personality Inventory (MMPI), the Profile of Mood States (POMS), the 36-item Short-form Health Survey version 2 (SF-36 v2), and the Roland-Morris Disability Questionnaire (RDQ) were conducted. The BS-POP, POMS, SF-36 v2, and RDQ for the third test were conducted (4-6 weeks after treatment) on all patients who had participated in the first test to determine the responsiveness of the BS-POP. The responsiveness of the BS-POP was investigated statistically. RESULTS: The total crude BS-POP scores were significantly lower for both physician and patient versions in the third test than in the first test. Moreover, the crude RDQ scores and SF-36 v2 items, physical functioning (PF), bodily pain (BP), MH, VT, and GH, and POMS items, tension-anxiety (T-A), D, F, and confusion (C) improved significantly, confirming responsiveness to treatment. DISCUSSION: The present findings indicate that the BS-POP possesses sufficient responsiveness from a computational psychology perspective. The BS-POP constitutes a tool enabling orthopaedists to easily identify psychiatric problems in orthopaedic patients.


Assuntos
Dor Lombar/psicologia , Escalas de Graduação Psiquiátrica , Avaliação da Deficiência , Feminino , Humanos , Japão , Masculino , Pessoa de Meia-Idade , Medição da Dor , Reprodutibilidade dos Testes
5.
Hum Psychopharmacol ; 29(2): 199-202, 2014 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-24590545

RESUMO

OBJECTIVE: Blonanserin is a novel atypical antipsychotic drug that has efficacy equal to risperidone. We investigated the effects of aripiprazole and blonanserin on clinical symptoms and plasma levels of homovanillic acid (pHVA) and 3-methoxy-4hydroxyphenylglycol in the switching strategy of schizophrenia. METHODS: Twenty two Japanese patients with schizophrenia were enrolled into this open study. The antipsychotics of all patients were switched to aripiprazole or blonanserin for the improvement of clinical symptoms or side effects. Plasma monoamine metabolites levels were analyzed with high-performance liquid chromatography. RESULTS: There were no significant effects for time (p = 0.346) or time × group interaction (p = 0.27) on the changes of positive and negative syndrome scale (PANSS) total score, although blonanserin decreased PANSS scores. We observed negative correlation between pHVA at baseline and the change in PANSS total score (rs = -0.450, p = 0.046). We also found positive correlation between the changes in pHVA and the changes in PANSS total (rs = 0.536, p = 0.015) and positive (rs = 0.572, p = 0.008) scores. CONCLUSIONS: There were no differences between blonanserin and aripiprazole in the improvement of clinical symptoms. Our results suggest that pHVA may be useful indicator for the switching strategy to aripiprazole or blonanserin in schizophrenia.


Assuntos
Antipsicóticos/uso terapêutico , Ácido Homovanílico/sangue , Piperazinas/uso terapêutico , Piperidinas/uso terapêutico , Quinolonas/uso terapêutico , Esquizofrenia/sangue , Esquizofrenia/tratamento farmacológico , Adulto , Antipsicóticos/efeitos adversos , Aripiprazol , Cromatografia Líquida de Alta Pressão , Feminino , Humanos , Japão , Masculino , Metoxi-Hidroxifenilglicol/sangue , Pessoa de Meia-Idade , Piperazinas/efeitos adversos , Piperidinas/efeitos adversos , Escalas de Graduação Psiquiátrica , Quinolonas/efeitos adversos , Fatores de Tempo , Resultado do Tratamento
6.
Psychiatry Clin Neurosci ; 68(3): 182-7, 2014 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-24895734

RESUMO

AIM: The Fukushima disaster was caused by an earthquake that occurred on 11 March 2011. Following the serious damage caused by the earthquake and the subsequent tsunami, radioactive contamination occurred because of the meltdown accident at the Fukushima nuclear power plant. We investigated what mental disorders were likely to become exacerbated under these conditions. METHODS: We surveyed psychiatric outpatients at Fukushima Medical University Hospital for 1 month (31 days) from the day of the earthquake (March­April 2011). RESULTS: The survey revealed that bipolar I disorder was most likely to become exacerbated under the conditions and that the exacerbation exhibited was more likely to involve manic switches than depression. CONCLUSION: On the basis of the results of our study, particular care must be taken to follow up bipolar I disorder patients after a natural disaster. Our results also suggested the possible origin of bipolar I disorder.


Assuntos
Terremotos , Acidente Nuclear de Fukushima , Transtornos Mentais/diagnóstico , Tsunamis , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Criança , Feminino , Humanos , Japão , Masculino , Transtornos Mentais/psicologia , Pessoa de Meia-Idade , Índice de Gravidade de Doença , Adulto Jovem
7.
J Clin Psychopharmacol ; 32(1): 106-9, 2012 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-22198450

RESUMO

The Taq1A polymorphism in the dopamine D2 receptor (DRD2) gene could be related to the response to antipsychotics. We examined the effects of the Taq1A polymorphism on the plasma monoamine metabolites during the treatment of schizophrenia with aripiprazole, a DRD2 partial agonist. Thirty Japanese patients with schizophrenia were treated with aripiprazole for 6 weeks. We measured plasma levels of homovanillic acid (pHVA) and 3-methoxy-4hydroxyphenylglycol (pMHPG) before and after treatment. The Taq1A polymorphism was genotyped with polymerase chain reaction. Aripiprazole improved the acute symptoms of schizophrenia and decreased pHVA in responders (P = 0.023) but not in nonresponders (P = 0.28). Although A1 allele carriers showed a tendency to respond to aripiprazole (61.5%) compared to A1 allele noncarriers (29.4%) (P = 0.078), there was not statistically significant difference in the response between the 2 genotype groups. There were significant effect for response (P = 0.013) and genotype × response interaction (P = 0.043) on the change of pHVA. The changes of pHVA differ between responders and nonresponders in A1 allele carriers but not in A1 allele noncarriers. There were no genotype or response effects or genotype × response interaction on the changes of the plasma levels of 3-methoxy-4hydroxyphenylglycol. Our preliminary results suggest that Taq1A polymorphism may be partly associated with changes in pHVA during acute schizophrenia.


Assuntos
Alelos , Antipsicóticos/uso terapêutico , Ácido Homovanílico/sangue , Metoxi-Hidroxifenilglicol/sangue , Piperazinas/uso terapêutico , Polimorfismo Genético/genética , Quinolonas/uso terapêutico , Receptores de Dopamina D2/genética , Esquizofrenia/sangue , Esquizofrenia/tratamento farmacológico , Esquizofrenia/genética , Taq Polimerase/genética , Doença Aguda , Adulto , Antipsicóticos/efeitos adversos , Aripiprazol , Feminino , Triagem de Portadores Genéticos , Genótipo , Humanos , Japão , Masculino , Pessoa de Meia-Idade , Piperazinas/efeitos adversos , Escalas de Graduação Psiquiátrica , Quinolonas/efeitos adversos , Receptores de Dopamina D2/agonistas , Resultado do Tratamento , Adulto Jovem
8.
Hum Psychopharmacol ; 27(5): 517-20, 2012 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-22927115

RESUMO

OBJECTIVE: In the treatment of acute schizophrenia, risperidone and aripiprazole are both placed the first line antipsychotics. These two antipsychotics have different pharmacological effects. We investigated the effects of risperidone on plasma levels of homovanillic acid (HVA) and 3-methoxy-4hydroxyphenylglycol after unsuccessful aripiprazole treatment in acute schizophrenia. METHODS: Ten Japanese patients with acute schizophrenia were enrolled to this study. Plasma levels of monoamine metabolites were analyzed with high-performance liquid chromatography with electrochemical detection. RESULTS: Risperidone improved the symptoms and 4 of 10 patients were responders. Risperidone showed a tendency to decrease plasma HVA (pHVA) levels in responders (p = 0.068), but not in non-responders (p = 1.0). At baseline, pHVA levels of responders were significantly higher than that of non-responders (p = 0.033). A trend for negative correlation was found between pHVA at baseline and the changes in Positive and Negative Syndrome Scale-Total (p = 0.061, r = -0.61). CONCLUSION: Our results suggest that high pHVA level before switching may predict good response to the second line antipsychotics after unsuccessful first antipsychotic treatment. If aripiprazole is not effective in acute schizophrenia, switching to risperidone may be effective and reasonable strategy for improving symptoms.


Assuntos
Antipsicóticos/uso terapêutico , Piperazinas/uso terapêutico , Quinolonas/uso terapêutico , Risperidona/uso terapêutico , Esquizofrenia/tratamento farmacológico , Doença Aguda , Adulto , Aripiprazol , Cromatografia Líquida de Alta Pressão , Feminino , Ácido Homovanílico/sangue , Humanos , Japão , Masculino , Metoxi-Hidroxifenilglicol/sangue , Pessoa de Meia-Idade , Escalas de Graduação Psiquiátrica , Resultado do Tratamento , Adulto Jovem
9.
Soc Sci Med ; 296: 114723, 2022 03.
Artigo em Inglês | MEDLINE | ID: mdl-35063915

RESUMO

INTRODUCTION: Unequal distribution of access to resources would often be highlighted after disasters, and may have impact on child mental health. We aimed to elucidate the association between perception of recovery process (dissatisfaction and perceived inequality) and child mental health. METHOD: Data from the Great East Japan Earthquake Follow-up for Children (GEJE-FC) study targeting children (aged 4-6 years at the time of the disaster) and their siblings and parents from three affected prefectures (Miyagi, Fukushima and Iwate) in Japan, from August 2012 to January 2018, were analyzed. Dissatisfaction and perceived inequality of recovery process, parental mental health (Kessler Psychological Distress Scale (K6) and happiness) and social capital, and child mental health (Depression Self-Rating Scale for Children) were assessed via self-rated questionnaires. Longitudinal associations of dissatisfaction and perceived inequality and mental health were examined with the linear mixed modeling and structural equation modeling (n = 168 parent-child dyads). RESULT: Dissatisfaction and perceived inequality predicted lower parental happiness and more child depressive symptoms. Structural equation modeling revealed that parental mental health was associated with perceived inequality via lower social capital. Interestingly, perceived inequality was associated with child depressive symptom directly and indirectly through parental mental health and social capital. CONCLUSION: Dissatisfaction and perceived inequality of post-disaster recovery process were important predictors of child mental health. To mitigate the impact of disaster and to avoid damage on child mental health in the recovery process, policy makers should take into account survivors' dissatisfaction and perceived inequality of recovery process.


Assuntos
Desastres , Terremotos , Humanos , Japão , Saúde Mental , Pais , Sobreviventes/psicologia
10.
J Psychiatr Res ; 151: 642-648, 2022 07.
Artigo em Inglês | MEDLINE | ID: mdl-35661521

RESUMO

Experience of natural disaster was related to an increased risk of long-term child internalizing problems. Initial traumatic experiences are hypothesized to work as disaster-related stresses and sensitize neural circuitry, leading to heightened reactivity to subsequent stressful experiences, which in turn results in delayed onset of internalizing problems. However, empirical evidence is lacking. Thus, we aimed to examine the association between heart rate variability (HRV) and internalizing problems among children exposed to the disaster. The Great East Japan Earthquake Follow-up for Children (GEJE-FC) study followed children aged 4-6 years old and their siblings and parents from three affected prefectures (Miyagi, Fukushima, and Iwate) and one unaffected prefecture (Mie) in Japan over four periods: from August 2012 to June 2013 (= T1), August 2013 to April 2014 (= T2), July 2014 to December 2014 (= T3), and August 2015 to December 2015 (= T4) (n = 155). HRV was assessed at T2 and T3 as a biomarker of autonomic nervous system activity. Child internalizing problems were assessed by caregivers at T3 and T4, using the Child Behavior Checklist. HRV measurements at T2 were not associated with child internalizing problems at T3. However, HRV in low frequency domains at T3 showed an inverse association with child internalizing problems at T4 (B = -1.72, 95% CI = -3.12 to -0.31). The findings indicated that later exacerbation of internalizing problems could be predicted by dysfunction of autonomic nervous system measured by HRV.


Assuntos
Desastres , Terremotos , Cuidadores , Criança , Pré-Escolar , Frequência Cardíaca , Humanos , Japão/epidemiologia
11.
J Pharmacol Sci ; 117(1): 45-53, 2011.
Artigo em Inglês | MEDLINE | ID: mdl-21869566

RESUMO

Ecto-5'-nucleotidase (NT5E), a predominant enzyme that produces extracellular adenosine from AMP, plays an important role in a variety of physiological and pathophysiological processes. This study was performed to identify agents that affect NT5E activity using C6 glioma cells. When cells were incubated with sodium nitroprusside (SNP), phorbol 12-myristate 13-acetate, forskolin, lipopolysaccharide, or interferon-γ, only SNP inhibited NT5E activity in a time- and concentration-dependent manner (IC(50) = 1.2 µM). The inhibitory effect of SNP was long-lasting even after SNP washout; and its action was not mimicked by nitric oxide generating agents, 8-bromo cyclic GMP, ferricyanide, ferrocyanide, or sodium cyanide. SNP did not change NT5E mRNA level or membrane surface protein expression. Similar to SNP, Fe(2+) inhibited NT5E activity, but to a lesser extent. Although Fe(2+) is known to increase oxidative stress, Fe(2+)-mediated oxidative stress was not involved in SNP inhibition of NT5E because the inhibition of NT5E by SNP was not affected by superoxide dismutase and catalase. In contrast, addition of Zn(2+), an essential metal co-factor of NT5E activity, prevented SNP from inhibiting NT5E. These results suggest that SNP disrupts a critical Zn(2+)-dependent enzyme activity and might be useful as a pharmacological tool for inhibiting NT5E.


Assuntos
Neoplasias Encefálicas/metabolismo , Glioma/metabolismo , Nitroprussiato/uso terapêutico , 5'-Nucleotidase , Sequência de Bases , Neoplasias Encefálicas/patologia , Linhagem Celular Tumoral , Primers do DNA , Glioma/patologia , Humanos , Reação em Cadeia da Polimerase Via Transcriptase Reversa
12.
J Orthop Sci ; 16(1): 7-13, 2011 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-21267612

RESUMO

INTRODUCTION: We developed the Brief Scale for Psychiatric problems in Orthopaedic Patients (BS-POP) (doctor and patient versions). The present study aimed to proactively verify the factorial validity, internal consistency, criterion-related validity and reproducibility of the BS-POP with regard to chronic low back pain patients. METHODS: Subjects comprised 193 chronic low back pain patients. During the first test, the BS-POP, Minnesota Multiphasic Personality Inventory (MMPI), Profile of Mood States (POMS) and 36-Item Short-Form Health Survey version 2 (SF-36 v2) were conducted. In the second test, patients were asked to complete the BS-POP in order to verify BS-POP reproducibility. RESULTS: Factor analysis demonstrated the factorial validity of the BS-POP, including 1-factor structure. Internal consistency was confirmed by Cronbach's α reliability coefficients of 0.794 (doctor version) and 0.750 (patient version). Criterion-related validity was confirmed through association with the psychosocial factors of the SF-36, the MMPI, and the POMS. The correlation coefficients for the retests were r = 0.654 (doctor version) and r = 0.719 (patient version), showing reproducibility. DISCUSSION: The present findings indicate that the BS-POP possesses sufficient reliability regarding computational psychology. The BS-POP constitutes a tool enabling orthopaedists themselves to easily identify psychiatric problems in orthopaedic patients. Further study is required regarding responsiveness.


Assuntos
Avaliação da Deficiência , Dor Lombar/diagnóstico , Programas de Rastreamento/métodos , Psicometria/métodos , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Doença Crônica , Feminino , Humanos , Japão , Dor Lombar/psicologia , Dor Lombar/reabilitação , Masculino , Pessoa de Meia-Idade , Medição da Dor , Reprodutibilidade dos Testes , Adulto Jovem
13.
Fukushima J Med Sci ; 67(2): 71-82, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34456222

RESUMO

The Great East Japan Earthquake severely damaged the Tohoku and Kanto districts, and Fukushima Prefecture faced a subsequent nuclear disaster. Few studies have reported the effects of socioeconomic stressors on individuals' mental status following disasters. We analyzed the responses of 60,704 adult residents of a designated restricted area to the PTSD Checklist-Stressor-Specific Version (PCL-S). The relationships between the PCL-S scores and demographic, socioeconomic, and damage-related variables were analyzed using regression analysis to predict participants' severity of PTSD symptoms. Approximately 14.1% of evacuees had severe PTSD symptoms (PCL-S ≥50) eighteen months post-earthquake. The PCL-S scores were higher among women, older adults, less educated people, those with a history of mental illness, and those living outside Fukushima Prefecture. The PCL-S scores increased with participants' scores on the Kessler Psychological Distress Scale. The number of trauma-exposure stressors and socioeconomic stressors were associated with 1.52 and 3.77 increases in the PCL-S score, respectively. Furthermore, psychological distress, unemployment, decreased income, house damage, tsunami experience, nuclear power plant accident experience, and loss of someone close due to the disaster were associated with the prevalence of severe PTSD symptoms. The complex triple disaster of a major earthquake, tsunami, and nuclear accident created significant socioeconomic changes that may be important determinants of PTSD among residents of restricted access areas in Fukushima.


Assuntos
Terremotos , Acidente Nuclear de Fukushima , Transtornos de Estresse Pós-Traumáticos , Idoso , Feminino , Humanos , Centrais Nucleares , Classe Social , Transtornos de Estresse Pós-Traumáticos/epidemiologia , Transtornos de Estresse Pós-Traumáticos/etiologia
14.
Fukushima J Med Sci ; 67(1): 8-16, 2021 Apr 10.
Artigo em Inglês | MEDLINE | ID: mdl-33583861

RESUMO

INTRODUCTION: We evaluated the mental health status of children residing in Kawauchi village (Kawauchi), Fukushima Prefecture, after the 2011 accident at the Fukushima Daiichi Nuclear Power Station, based on the children's experience of the nuclear disaster. METHODS: We conducted this cross-sectional study within the framework of the Fukushima Health Management Survey (FHMS);FHMS data on age, sex, exercise habits, sleeping times, experience of the nuclear disaster, and the "Strengths and Difficulties Questionnaire (SDQ)" scores for 156 children from Kawauchi in 2012 were collected. Groups with and without experience of the nuclear disaster - "nuclear disaster (+)" and "nuclear disaster (-)" - were also compared. RESULTS: Our effective response was 93 (59.6%);the mean SDQ score was 11.4±6.8 among elementary school-aged participants and 12.4±6.8 among junior high school-aged ones. We statistically compared the Total Difficulties Scores (TDS) and sub-item scores of the SDQ between "elementary school" and "junior high school" or "nuclear disaster" (+) and (-). There was no significant difference between these items. CONCLUSIONS: We found indications of poor mental health among elementary and junior high school-aged children in the disaster area immediately following the accident, but no differences based on their experience of the nuclear disaster. These results indicate the possibility of triggering stress, separate to that from experiences related to the nuclear disaster, in children who lived in affected rural areas and were evacuated just after the nuclear disaster.


Assuntos
Desastres , Acidente Nuclear de Fukushima , Criança , Estudos Transversais , Nível de Saúde , Inquéritos Epidemiológicos , Humanos , Japão/epidemiologia
16.
PLoS One ; 15(12): e0243994, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-33378366

RESUMO

Delay discounting is an important predictor of future health and academic success in children but can change in environmental uncertainty situations. Here we show that the experience of loss of housing in the Great East Japan Earthquake 2011-but not other psychological trauma such as loss of loved ones-was correlated delay discounting of children. In 2014, we assessed delay discounting in children (N = 167; mean age = 8.3 years-old), who were preschool age at the time of the earthquake (mean age at the time of disaster = 4.8 years-old) in a time-investment exercise where children allocated five tokens between rewards "now" (one candy per token on the same day) versus "one month later" (two candies per token one month later). The number of tokens allocated for "now" was higher by 0.535 (95% confidence interval: -0.012, 1.081) in children who had their housing destroyed or flooded than those with no housing damage. Other types of traumatic experiences were not associated with delay discounting.


Assuntos
Desvalorização pelo Atraso , Sobreviventes/psicologia , Criança , Terremotos , Feminino , Humanos , Japão , Masculino
17.
Fukushima J Med Sci ; 66(3): 133-142, 2020 Dec 10.
Artigo em Inglês | MEDLINE | ID: mdl-32981903

RESUMO

Introduction Traumatic experiences and disordered sleep are strongly associated with drinking problems. We examined the effects of experiencing the Great East Japan Earthquake and subsequent nuclear power plant accident, and of sleep problems, on behavioral changes observed in non-drinkers.Methods This study examined cross-sectional data from the Mental Health and Lifestyle Survey conducted among residents in restricted areas of Fukushima in 2012. Participants were 21,454 evacuees aged 20 years or older at the time of disaster. People who did not drink before the disaster but became drinkers afterwards were compared with the rest of the cohort. We analyzed the association between behavioral changes in non-drinkers and potentially predictive variables, using logistic regression.Results The behavioral change of non-drinkers becoming drinkers (n=2,148) was significantly related to being male (OR=1.93, 95% CI:1.74-2.15), being younger (21-49 yrs, OR=1.85, 95% CI: 1.60-2.13), having less educational attainment (up to high school graduate, OR=1.21, 95% CI:1.09-1.35), smoking (OR=1.22, 95% CI:1.08-1.38), losing family or relatives (OR=1.21, 95% CI:1.07-1.37), change in employment (OR=1.19, 95% CI:1.07-1.32), having severe sleep problems as measured by a Japanese version of the Athens Insomnia Scale (3-8, OR=1.45, 95% CI:1.30-1.62), and severity of traumatic symptoms as measured by the PTSD Checklist Stressor-Specific (PCL-S) score (<44, OR=1.33, 95% CI:1.17-1.51).Conclusion Having sleep problems and having more severe traumatic symptoms are significantly related to non-drinkers becoming drinkers.


Assuntos
Comportamento de Ingestão de Líquido/efeitos da radiação , Acidente Nuclear de Fukushima , Adulto , Idoso , Idoso de 80 Anos ou mais , Estudos Transversais , Feminino , Humanos , Modelos Logísticos , Masculino , Pessoa de Meia-Idade , Inquéritos e Questionários , Adulto Jovem
19.
Front Psychiatry ; 10: 45, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-30837900

RESUMO

Objective: The purpose of this study was to investigate the influence of parenting style on children's behavior problems after the Great East Japan Earthquake in 2011. Methods: Participants were children exposed to the 2011 disaster at preschool age (n = 163). Data were collected from August 2012 to March 2013, and from July 2014 to March 2015 (2 and 4 years, respectively, after the earthquake), thus participants were aged 4-11 years when assessed. Parenting style was assessed by caregivers using the Alabama Parenting Questionnaire (APQ), which measures parental involvement, positive parenting, poor monitoring/supervision, inconsistent discipline, and corporal punishment in the second year after the disaster. Behavior problems were assessed by caregivers using the Child Behavior Checklist (CBCL), which identifies internalizing, externalizing, and total problems in the second and fourth year after the disaster. Results: The results show that corporal punishment in the second year after the disaster had negative influence on CBCL internalizing score (coefficient: 0.78, 95%CI: 0.12-1.45, p = 0.023), externalizing score (coefficient: 0.74, 95%CI: 0.09-1.39, p = 0.025), and total score in the fourth year after the disaster (coefficient: 0.85, 95%CI: 0.16-1.55, p = 0.016), after adjusted for children's age, sex, the number of trauma experiences, maternal education, the number of siblings, temporally housing experience, and CBCL each scores in the second year after the disaster. Other parenting style did not affect children's behavioral problems. Conclusion: The result suggests that inadequate rearing after a natural disaster had negative impact on the behavior problems of the affected children in 4 years later of the disaster. Specifically, corporal punishment had negative influence on children's behavior problems.

20.
Hypertens Res ; 42(8): 1215-1222, 2019 08.
Artigo em Inglês | MEDLINE | ID: mdl-30903093

RESUMO

The 11 March 2011 earthquake and tsunami in Japan resulted in ~19,000 lost lives and the displacement of nearly a quarter million people owing to extensive property damage and evacuation from the nuclear meltdown in Fukushima. We sought to prospectively examine whether exposure to disaster-related trauma affected blood pressure levels among young children. We sampled children in three affected prefectures (Miyagi, Fukushima, Iwate) and one unaffected prefecture (Mie). The participants (mean age 6.6 years) and their caregivers answered a baseline survey (N = 320) and a follow-up survey 4 years after the earthquake (N = 227, follow-up rate 71%). Disaster-related trauma was assessed at the baseline, and blood pressure measurements were taken at the follow-up. We converted blood pressure data into age/sex/height-specific z-scores. In linear regression models, we controlled for body mass index, income, age, sex, and housing situation (living in the same house as before the disaster, in a shelter, or in a new house). The number of traumatic experiences was related to diastolic blood pressure in a dose-dependent manner but was not related to systolic blood pressure. Children reporting four or more traumatic experiences had marginally significant elevated diastolic blood pressure (ß = 0.43, p = 0.059). Among specific types of disaster trauma, witnessing a fire was significantly related to higher diastolic blood pressure (ß = 0.60, p = 0.009). In conclusion, disaster-related trauma was associated with higher diastolic blood pressure among young children 4 years after the traumatic events.


Assuntos
Pressão Sanguínea , Desastres , Terremotos , Trauma Psicológico/fisiopatologia , Criança , Pré-Escolar , Diástole , Feminino , Seguimentos , Humanos , Japão , Masculino
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