Exome sequencing deciphers rare diseases.

Two years ago, NIH's Undiagnosed Diseases Program began delivering genomics to the clinic on an unprecedented scale. Now, with 128 exomes sequenced and 39 rare diseases diagnosed, the program's success is paving the way for widespread personal genomics while pioneering new techniques for reigning in the "tsunami" of genomics data.

Video games and the second life of science class.

Can video games and computer simulations revive science education in the US? Amy Maxmen has the story.

Driving innovation: ready, set, go!

In our increasingly networked world, prizes are gaining a foothold in the race for innovation in science and technology. Amy Maxmen reports.

Science networking gets serious.

A new breed of networking applications offers scientists much more than typical social networking sites, but how useful are they? Amy Maxmen reports.

Will scientists cast their votes?

With science and technology high on the agenda of the new US administration, scientists should welcome the opportunity to influence policy. However, few academic scientists seem to be noticing proposals posted for public comment on the Federal Register that concern the application of science to society.

Taking risks to transform science.

Tackling long-standing problems in science or refuting dogma is not necessarily the best strategy for a young investigator seeking tenure. But just like investing in risky stocks when young, perhaps it should be. Amy Maxmen reports.