Detalhe da pesquisa
1.
An intestinal zinc sensor regulates food intake and developmental growth.
Nature;
580(7802): 263-268, 2020 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32269334
2.
Ret receptor tyrosine kinase sustains proliferation and tissue maturation in intestinal epithelia.
EMBO J;
36(20): 3029-3045, 2017 10 16.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28899900
3.
FXR Isoforms Control Different Metabolic Functions in Liver Cells via Binding to Specific DNA Motifs.
Gastroenterology;
159(5): 1853-1865.e10, 2020 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32712104
4.
Farnesoid X Receptor Activation Promotes Hepatic Amino Acid Catabolism and Ammonium Clearance in Mice.
Gastroenterology;
152(6): 1462-1476.e10, 2017 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28130067
5.
Splenic dendritic cell involvement in FXR-mediated amelioration of DSS colitis.
Biochim Biophys Acta;
1862(2): 166-73, 2016 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26554605
6.
Characterization of stem cell-derived liver and intestinal organoids as a model system to study nuclear receptor biology.
Biochim Biophys Acta Mol Basis Dis;
1863(3): 687-700, 2017 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27956139
7.
Gene expression profiling in human precision cut liver slices in response to the FXR agonist obeticholic acid.
J Hepatol;
64(5): 1158-1166, 2016 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26812075
8.
Anti-inflammatory and metabolic actions of FXR: insights into molecular mechanisms.
Biochim Biophys Acta;
1821(11): 1443-52, 2012 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22820415
9.
Dax1 modulates ERα-dependent hypothalamic estrogen sensing in female mice.
Nat Commun;
14(1): 3076, 2023 05 29.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37248237
10.
Raised hepatic bile acid concentrations during pregnancy in mice are associated with reduced farnesoid X receptor function.
Hepatology;
52(4): 1341-9, 2010 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20842631
11.
The normal mechanisms of pregnancy-induced liver growth are not maintained in mice lacking the bile acid sensor Fxr.
Am J Physiol Gastrointest Liver Physiol;
298(2): G151-8, 2010 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19815629
12.
Intestinal detoxification limits the activation of hepatic pregnane X receptor by lithocholic acid.
Drug Metab Dispos;
38(1): 143-9, 2010 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19797606
13.
Live Birth in Sex-Reversed XY Mice Lacking the Nuclear Receptor Dax1.
Sci Rep;
10(1): 1703, 2020 02 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32015477
14.
Steroidogenic control of liver metabolism through a nuclear receptor-network.
Mol Metab;
30: 221-229, 2019 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31767173
15.
Quantitative liver proteomics identifies FGF19 targets that couple metabolism and proliferation.
PLoS One;
12(2): e0171185, 2017.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28178326
16.
The glucocorticoid mometasone furoate is a novel FXR ligand that decreases inflammatory but not metabolic gene expression.
Sci Rep;
5: 14086, 2015 Sep 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26369990
17.
Functional variants of the central bile acid sensor FXR identified in intrahepatic cholestasis of pregnancy.
Gastroenterology;
133(2): 507-16, 2007 Aug.
Artigo
em Inglês
| MEDLINE
| ID: mdl-17681172