Detalhe da pesquisa
1.
Rare variants in long non-coding RNAs are associated with blood lipid levels in the TOPMed whole-genome sequencing study.
Am J Hum Genet;
110(10): 1704-1717, 2023 10 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37802043
2.
A framework for detecting noncoding rare-variant associations of large-scale whole-genome sequencing studies.
Nat Methods;
19(12): 1599-1611, 2022 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36303018
3.
In-Depth Mass Spectrometry Analysis Reveals the Plasma Proteomic and N-Glycoproteomic Impact of an Amish-Enriched Cardioprotective Variant in B4GALT1.
Mol Cell Proteomics;
22(8): 100595, 2023 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37328064
4.
Pharmacogenetics of sodium-glucose co-transporter-2 inhibitors: Validation of a sex-agnostic pharmacodynamic biomarker.
Diabetes Obes Metab;
25(12): 3512-3520, 2023 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37608471
5.
Acute pharmacodynamic responses to exenatide: Drug-induced increases in insulin secretion and glucose effectiveness.
Diabetes Obes Metab;
25(9): 2586-2594, 2023 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37264484
6.
Rare coding variants in RCN3 are associated with blood pressure.
BMC Genomics;
23(1): 148, 2022 Feb 19.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35183128
7.
DNA Methylation Analysis Identifies Loci for Blood Pressure Regulation.
Am J Hum Genet;
101(6): 888-902, 2017 Dec 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29198723
8.
An APOO Pseudogene on Chromosome 5q Is Associated With Low-Density Lipoprotein Cholesterol Levels.
Circulation;
138(13): 1343-1355, 2018 09 25.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29593015
9.
Leveraging linkage evidence to identify low-frequency and rare variants on 16p13 associated with blood pressure using TOPMed whole genome sequencing data.
Hum Genet;
138(2): 199-210, 2019 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30671673
10.
Disruption of ldlr causes increased LDL-c and vascular lipid accumulation in a zebrafish model of hypercholesterolemia.
J Lipid Res;
55(11): 2242-53, 2014 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25201834
11.
Critical Role for 24-Hydroxylation in Homeostatic Regulation of Vitamin D Metabolism.
medRxiv;
2024 Mar 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37425945
12.
Vitamin D Deficiency Increases Vulnerability to Canagliflozin-induced Adverse Effects on 1,25-Dihydroxyvitamin D and PTH.
J Clin Endocrinol Metab;
109(2): e646-e656, 2024 Jan 18.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37738423
13.
Acute pharmacodynamic responses to sitagliptin: Drug-induced increase in early insulin secretion in oral glucose tolerance test.
Clin Transl Sci;
17(5): e13809, 2024 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38700326
14.
Critical Role for 24-Hydroxylation in Homeostatic Regulation of Vitamin D Metabolism.
J Clin Endocrinol Metab;
2024 Mar 14.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38481375
15.
Vitamin D deficiency increases vulnerability to canagliflozin-induced adverse effects on 1,25-dihydroxyvitamin D and PTH.
medRxiv;
2023 Aug 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37214882
16.
Acute pharmacodynamic responses to sitagliptin: Drug-induced increase in early insulin secretion in oral glucose tolerance test.
medRxiv;
2023 Oct 19.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37808823
17.
Pharmacogenetics of SGLT2 Inhibitors: Validation of a sex-agnostic pharmacodynamic biomarker.
medRxiv;
2023 Jun 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36945579
18.
Acute pharmacodynamic responses to exenatide: Drug-induced increases in insulin secretion and glucose effectiveness.
medRxiv;
2023 May 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36993363
19.
Powerful, scalable and resource-efficient meta-analysis of rare variant associations in large whole genome sequencing studies.
Nat Genet;
55(1): 154-164, 2023 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36564505
20.
Carriers of rare damaging CCR2 genetic variants are at lower risk of atherosclerotic disease.
medRxiv;
2023 Aug 16.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37645892