Detalhe da pesquisa
1.
Membrane extraction by calmodulin underpins the disparate signalling of RalA and RalB.
Bioessays;
44(6): e2200011, 2022 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35318680
2.
Calmodulin extracts the Ras family protein RalA from lipid bilayers by engagement with two membrane-targeting motifs.
Proc Natl Acad Sci U S A;
118(36)2021 09 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34480001
3.
Assembly of nuclear dimers of PI3K regulatory subunits is regulated by the Cdc42-activated tyrosine kinase ACK.
J Biol Chem;
298(6): 101916, 2022 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35429500
4.
Affinity maturation of the RLIP76 Ral binding domain to inform the design of stapled peptides targeting the Ral GTPases.
J Biol Chem;
296: 100101, 2021.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33214225
5.
A Complete Survey of RhoGDI Targets Reveals Novel Interactions with Atypical Small GTPases.
Biochemistry;
60(19): 1533-1551, 2021 05 18.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33913706
6.
The discovery and maturation of peptide biologics targeting the small G-protein Cdc42: A bioblockade for Ras-driven signaling.
J Biol Chem;
295(9): 2866-2884, 2020 02 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31959628
7.
Progress in the therapeutic inhibition of Cdc42 signalling.
Biochem Soc Trans;
49(3): 1443-1456, 2021 06 30.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34100887
8.
The structure and function of protein kinase C-related kinases (PRKs).
Biochem Soc Trans;
49(1): 217-235, 2021 02 26.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33522581
9.
Molecular subversion of Cdc42 signalling in cancer.
Biochem Soc Trans;
49(3): 1425-1442, 2021 06 30.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34196668
10.
Bioblockades join the assault on small G protein signalling.
Semin Cancer Biol;
54: 149-161, 2019 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29307570
11.
Class IA PI3K regulatory subunits: p110-independent roles and structures.
Biochem Soc Trans;
48(4): 1397-1417, 2020 08 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32677674
12.
Activation of STAT transcription factors by the Rho-family GTPases.
Biochem Soc Trans;
48(5): 2213-2227, 2020 10 30.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32915198
13.
Intrinsically disordered proteins and membranes: a marriage of convenience for cell signalling?
Biochem Soc Trans;
48(6): 2669-2689, 2020 12 18.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33155649
14.
Bond swapping from a charge cloud allows flexible coordination of upstream signals through WASP: Multiple regulatory roles for the WASP basic region.
J Biol Chem;
293(39): 15136-15151, 2018 09 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30104412
15.
A dock and coalesce mechanism driven by hydrophobic interactions governs Cdc42 binding with its effector protein ACK.
J Biol Chem;
292(27): 11361-11373, 2017 07 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28539360
16.
CRIB effector disorder: exquisite function from chaos.
Biochem Soc Trans;
46(5): 1289-1302, 2018 10 19.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30154092
17.
Allostery and dynamics in small G proteins.
Biochem Soc Trans;
46(5): 1333-1343, 2018 10 19.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30301845
18.
Structures of Ras superfamily effector complexes: What have we learnt in two decades?
Crit Rev Biochem Mol Biol;
50(2): 85-133, 2015.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25830673
19.
Investigation of the Interaction between Cdc42 and Its Effector TOCA1: HANDOVER OF Cdc42 TO THE ACTIN REGULATOR N-WASP IS FACILITATED BY DIFFERENTIAL BINDING AFFINITIES.
J Biol Chem;
291(26): 13875-90, 2016 Jun 24.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27129201
20.
Inhibition of Ral GTPases Using a Stapled Peptide Approach.
J Biol Chem;
291(35): 18310-25, 2016 08 26.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27334922