Detalhe da pesquisa
1.
Seralutinib in adults with pulmonary arterial hypertension (TORREY): a randomised, double-blind, placebo-controlled phase 2 trial.
Lancet Respir Med;
2024 May 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38705167
2.
Lack of a pharmacokinetic interaction between treprostinil diolamine and sildenafil in healthy adult volunteers.
J Cardiovasc Pharmacol;
61(5): 444-51, 2013 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23429588
3.
TORREY, a Phase 2 study to evaluate the efficacy and safety of inhaled seralutinib for the treatment of pulmonary arterial hypertension.
Pulm Circ;
11(4): 20458940211057071, 2021.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34790348
4.
Potent effects of aerosol compared with intravenous treprostinil on the pulmonary circulation.
J Appl Physiol (1985);
99(6): 2363-8, 2005 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-16141385
5.
Binding and activity of the prostacyclin receptor (IP) agonists, treprostinil and iloprost, at human prostanoid receptors: treprostinil is a potent DP1 and EP2 agonist.
Biochem Pharmacol;
84(1): 68-75, 2012 Jul 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22480736
6.
Lack of a pharmacokinetic interaction between oral treprostinil and bosentan in healthy adult volunteers.
J Clin Pharmacol;
50(7): 829-34, 2010 Jul.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20133511
7.
Functional selectivity of dopamine receptor agonists. I. Selective activation of postsynaptic dopamine D2 receptors linked to adenylate cyclase.
J Pharmacol Exp Ther;
301(3): 1166-78, 2002 Jun.
Artigo
em Inglês
| MEDLINE
| ID: mdl-12023552