Quality and antioxidant potential of goat's milk paneer prepared from different citrus juices and its whey.

The experiments reported in this research paper aimed to evaluate the physico-chemical and sensory characteristics, microbial quality and antioxidant potential of goat's milk paneer during storage (0-12 d, 4 ± 1°C). The juices from five different citrus fruits were used as coagulant (treatments) to make goat's milk paneer. The pH of all paneer samples decreased during storage whereas titratable acidity increased. Ash (%) fat (%) and protein (%) of paneer increased slightly during storage, whereas sensory perception decreased. The juices from all the citrus fruit varieties showed high contents of total phenolics and total flavonoids which ultimately influenced ferric reducing antioxidant power, total antioxidant capacity and radical scavenging activities. As the contents of different juices were also retained in the paneer matrix, so paneer coagulated with citrus juices also showed encouraging results in terms of total phenolic and flavonoid contents, ferric reducing antioxidant power and radical scavenging activities. Amongst all the paneers, the most promising was that coagulated by kinnow juice. In addition, the whey obtained from paneer coagulated by citrus juices also showed appreciable quantities of total phenolic and flavonoid contents, thereby beneficially influencing ferric reducing antioxidant power andradical scavenging activities. It is concluded that citrus juices improve the sensorial quality and antioxidant potential of goat's milk paneer and its whey.

Medical image-based detection of COVID-19 using Deep Convolution Neural Networks.

The demand for automatic detection of Novel Coronavirus or COVID-19 is increasing across the globe. The exponential rise in cases burdens healthcare facilities, and a vast amount of multimedia healthcare data is being explored to find a solution. This study presents a practical solution to detect COVID-19 from chest X-rays while distinguishing those from normal and impacted by Viral Pneumonia via Deep Convolution Neural Networks (CNN). In this study, three pre-trained CNN models (EfficientNetB0, VGG16, and InceptionV3) are evaluated through transfer learning. The rationale for selecting these specific models is their balance of accuracy and efficiency with fewer parameters suitable for mobile applications. The dataset used for the study is publicly available and compiled from different sources. This study uses deep learning techniques and performance metrics (accuracy, recall, specificity, precision, and F1 scores). The results show that the proposed approach produced a high-quality model, with an overall accuracy of 92.93%, COVID-19, a sensitivity of 94.79%. The work indicates a definite possibility to implement computer vision design to enable effective detection and screening measures.

Deep learning application detecting SARS-CoV-2 key enzymes inhibitors.

The fast spread of the COVID-19 over the world pressured scientists to find its cures. Especially, with the disastrous results, it engendered from human life losses to long-term impacts on infected people's health and the huge financial losses. In addition to the massive efforts made by researchers and medicals on finding safe, smart, fast, and efficient methods to accurately make an early diagnosis of the COVID-19. Some researchers focused on finding drugs to treat the disease and its symptoms, others worked on creating effective vaccines, while several concentrated on finding inhibitors for the key enzymes of the virus, to reduce its spreading and reproduction inside the human body. These enzymes' inhibitors are usually found in aliments, plants, fungi, or even in some drugs. Since these inhibitors slow and halt the replication of the virus in the human body, they can help fight it at an early stage saving the patient from death risk. Moreover, if the human body's immune system gets rid of the virus at the early stage it can be spared from the disastrous sequels it may leave inside the patient's body. Our research aims to find aliments and plants that are rich in these inhibitors. In this paper, we developed a deep learning application that is trained with various aliments, plants, and drugs to detect if a component contains SARS-CoV-2 key inhibitor(s) intending to help them find more sources containing these inhibitors. The application is trained to identify various sources rich in thirteen coronavirus-2 key inhibitors. The sources are currently just aliments, plants, and seeds and the identification is done by their names.

Proactive Caching in D2D Assisted Multitier Cellular Network.

Cache-enabled networks suffer hugely from the challenge of content caching and content delivery. In this regard, cache-enabled device-to-device (D2D) assisted multitier cellular networks are expected to relieve the network data pressure and effectively solve the problem of content placement and content delivery. Consequently, the user can have a better opportunity to get their favored contents from nearby cache-enabled transmitters (CETs) through reliable and good-quality links; however, as expected, designing an effective caching policy is a challenging task due to the limited cache memory of CETs and uncertainty in user preferences. In this article, we introduce a joint content placement and content delivery technique for D2D assisted multitier cellular networks (D2DMCN). A support vector machine (SVM) is employed to predict the content popularity to determine which content is to be cached and where it is to be cached, thereby increasing the overall cache hit ratio (CHR). The content request is satisfied either by the neighboring node through the D2D link or by the cache-enabled base stations (BSs) of the multitier cellular networks (MCNs). Similarly, to solve the problem of optimal content delivery, the Hungarian algorithm is employed aiming to improve the quality of satisfaction. The simulation results indicate that the proposed content placement strategy effectively optimizes the overall cache hit ratio of the system. Similarly, an effective content delivery approach reduces the request content delivery delay and power consumption.

Analysis of IoT-Related Ergonomics-Based Healthcare Issues Using Analytic Hierarchy Process Methodology.

The objective of the present work is for assessing ergonomics-based IoT (Internet of Things) related healthcare issues with the use of a popular multi-criteria decision-making technique named the analytic hierarchy process (AHP). Multiple criteria decision making (MCDM) is a technique that combines alternative performance across numerous contradicting, qualitative, and/or quantitative criteria, resulting in a solution requiring a consensus. The AHP is a flexible strategy for organizing and simplifying complex MCDM concerns by disassembling a compound decision problem into an ordered array of relational decision components (evaluation criteria, sub-criteria, and substitutions). A total of twelve IoT-related ergonomics-based healthcare issues have been recognized as Lumbago (lower backache), Cervicalgia (neck ache), shoulder pain; digital eye strain, hearing impairment, carpal tunnel syndrome; distress, exhaustion, depression; obesity, high blood pressure, hyperglycemia. "Distress" has proven itself the most critical IoT-related ergonomics-based healthcare issue, followed by obesity, depression, and exhaustion. These IoT-related ergonomics-based healthcare issues in four categories (excruciating issues, eye-ear-nerve issues, psychosocial issues, and persistent issues) have been compared and ranked. Based on calculated mathematical values, "psychosocial issues" have been ranked in the first position followed by "persistent issues" and "eye-ear-nerve issues". In several industrial systems, the results may be of vital importance for increasing the efficiency of human force, particularly a human-computer interface for prolonged hours.

Intelligent Tracking of Mechanically Thrown Objects by Industrial Catching Robot for Automated In-Plant Logistics 4.0.

Industry 4.0 smart manufacturing systems are equipped with sensors, smart machines, and intelligent robots. The automated in-plant transportation of manufacturing parts through throwing and catching robots is an attempt to accelerate the transportation process and increase productivity by the optimized utilization of in-plant facilities. Such an approach requires intelligent tracking and prediction of the final 3D catching position of thrown objects, while observing their initial flight trajectory in real-time, by catching robot in order to grasp them accurately. Due to non-deterministic nature of such mechanically thrown objects' flight, accurate prediction of their complete trajectory is only possible if we accurately observe initial trajectory as well as intelligently predict remaining trajectory. The thrown objects in industry can be of any shape but detecting and accurately predicting interception positions of any shape object is an extremely challenging problem that needs to be solved step by step. In this research work, we only considered spherical shape objects as their3D central position can be easily determined. Our work comprised of development of a 3D simulated environment which enabled us to throw object of any mass, diameter, or surface air friction properties in a controlled internal logistics environment. It also enabled us to throw object with any initial velocity and observe its trajectory by placing a simulated pinhole camera at any place within 3D vicinity of internal logistics. We also employed multi-view geometry among simulated cameras in order to observe trajectories more accurately. Hence, it provided us an ample opportunity of precise experimentation in order to create enormous dataset of thrown object trajectories to train an encoder-decoder bidirectional LSTM deep neural network. The trained neural network has given the best results for accurately predicting trajectory of thrown objects in real time.

A Novel QKD Approach to Enhance IIOT Privacy and Computational Knacks.

The industry-based internet of things (IIoT) describes how IIoT devices enhance and extend their capabilities for production amenities, security, and efficacy. IIoT establishes an enterprise-to-enterprise setup that means industries have several factories and manufacturing units that are dependent on other sectors for their services and products. In this context, individual industries need to share their information with other external sectors in a shared environment which may not be secure. The capability to examine and inspect such large-scale information and perform analytical protection over the large volumes of personal and organizational information demands authentication and confidentiality so that the total data are not endangered after illegal access by hackers and other unauthorized persons. In parallel, these large volumes of confidential industrial data need to be processed within reasonable time for effective deliverables. Currently, there are many mathematical-based symmetric and asymmetric key cryptographic approaches and identity- and attribute-based public key cryptographic approaches that exist to address the abovementioned concerns and limitations such as computational overheads and taking more time for crucial generation as part of the encipherment and decipherment process for large-scale data privacy and security. In addition, the required key for the encipherment and decipherment process may be generated by a third party which may be compromised and lead to man-in-the-middle attacks, brute force attacks, etc. In parallel, there are some other quantum key distribution approaches available to produce keys for the encipherment and decipherment process without the need for a third party. However, there are still some attacks such as photon number splitting attacks and faked state attacks that may be possible with these existing QKD approaches. The primary motivation of our work is to address and avoid such abovementioned existing problems with better and optimal computational overhead for key generation, encipherment, and the decipherment process compared to the existing conventional models. To overcome the existing problems, we proposed a novel dynamic quantum key distribution (QKD) algorithm for critical public infrastructure, which will secure all cyber-physical systems as part of IIoT. In this paper, we used novel multi-state qubit representation to support enhanced dynamic, chaotic quantum key generation with high efficiency and low computational overhead. Our proposed QKD algorithm can create a chaotic set of qubits that act as a part of session-wise dynamic keys used to encipher the IIoT-based large scales of information for secure communication and distribution of sensitive information.

Spatial Attention-Based 3D Graph Convolutional Neural Network for Sign Language Recognition.

Sign language is the main channel for hearing-impaired people to communicate with others. It is a visual language that conveys highly structured components of manual and non-manual parameters such that it needs a lot of effort to master by hearing people. Sign language recognition aims to facilitate this mastering difficulty and bridge the communication gap between hearing-impaired people and others. This study presents an efficient architecture for sign language recognition based on a convolutional graph neural network (GCN). The presented architecture consists of a few separable 3DGCN layers, which are enhanced by a spatial attention mechanism. The limited number of layers in the proposed architecture enables it to avoid the common over-smoothing problem in deep graph neural networks. Furthermore, the attention mechanism enhances the spatial context representation of the gestures. The proposed architecture is evaluated on different datasets and shows outstanding results.

Deep learning in multimedia healthcare applications: a review.

The increase in chronic diseases has affected the countries' health system and economy. With the recent COVID-19 virus, humanity has experienced a great challenge, which has led to make efforts to detect it and prevent its spread. Hence, it is necessary to develop new solutions that are based on technology and low cost, to satisfy the citizens' needs. Deep learning techniques is a technological solution that has been used in healthcare lately. Nowadays, with the increase in chips processing capabilities, increase size of data, and the progress in deep learning research, healthcare applications have been proposed to provide citizens' health needs. In addition, a big amount of data is generated every day. Development in Internet of Things, gadgets, and phones has allowed the access to multimedia data. Data such as images, video, audio and text are used as input of applications based on deep learning methods to support healthcare system to diagnose, predict, or treat patients. This review pretends to give an overview of proposed healthcare solutions based on deep learning techniques using multimedia data. We show the use of deep learning in healthcare, explain the different types of multimedia data, show some relevant deep learning multimedia applications in healthcare, and highlight some challenges in this research area.

Federated learning-based AI approaches in smart healthcare: concepts, taxonomies, challenges and open issues.

Federated Learning (FL), Artificial Intelligence (AI), and Explainable Artificial Intelligence (XAI) are the most trending and exciting technology in the intelligent healthcare field. Traditionally, the healthcare system works based on centralized agents sharing their raw data. Therefore, huge vulnerabilities and challenges are still existing in this system. However, integrating with AI, the system would be multiple agent collaborators who are capable of communicating with their desired host efficiently. Again, FL is another interesting feature, which works decentralized manner; it maintains the communication based on a model in the preferred system without transferring the raw data. The combination of FL, AI, and XAI techniques can be capable of minimizing several limitations and challenges in the healthcare system. This paper presents a complete analysis of FL using AI for smart healthcare applications. Initially, we discuss contemporary concepts of emerging technologies such as FL, AI, XAI, and the healthcare system. We integrate and classify the FL-AI with healthcare technologies in different domains. Further, we address the existing problems, including security, privacy, stability, and reliability in the healthcare field. In addition, we guide the readers to solving strategies of healthcare using FL and AI. Finally, we address extensive research areas as well as future potential prospects regarding FL-based AI research in the healthcare management system.

Sensor-Based Human Activity Recognition with Spatio-Temporal Deep Learning.

Human activity recognition (HAR) remains a challenging yet crucial problem to address in computer vision. HAR is primarily intended to be used with other technologies, such as the Internet of Things, to assist in healthcare and eldercare. With the development of deep learning, automatic high-level feature extraction has become a possibility and has been used to optimize HAR performance. Furthermore, deep-learning techniques have been applied in various fields for sensor-based HAR. This study introduces a new methodology using convolution neural networks (CNN) with varying kernel dimensions along with bi-directional long short-term memory (BiLSTM) to capture features at various resolutions. The novelty of this research lies in the effective selection of the optimal video representation and in the effective extraction of spatial and temporal features from sensor data using traditional CNN and BiLSTM. Wireless sensor data mining (WISDM) and UCI datasets are used for this proposed methodology in which data are collected through diverse methods, including accelerometers, sensors, and gyroscopes. The results indicate that the proposed scheme is efficient in improving HAR. It was thus found that unlike other available methods, the proposed method improved accuracy, attaining a higher score in the WISDM dataset compared to the UCI dataset (98.53% vs. 97.05%).

COVID-19 and Non-COVID-19 Classification using Multi-layers Fusion From Lung Ultrasound Images.

COVID-19 or related viral pandemics should be detected and managed without hesitation, since the virus spreads very rapidly. Often with insufficient human and electronic resources, patients need to be checked from stable patients using vital signs, radiographic photographs, or ultrasound images. Vital signs do not often offer the right outcome, and radiographic photos have a variety of other problems. Lung ultrasound (LUS) images can provide good screening without a lot of complications. This paper suggests a model of a convolutionary neural network (CNN) that has fewer learning parameters but can achieve strong accuracy. The model has five main blocks or layers of convolution connectors. A multi-layer fusion functionality of each block is proposed to improve the efficiency of the COVID-19 screening method utilizing the proposed model. Experiments are conducted using freely accessible LUS photographs and video datasets. The proposed fusion method has 92.5% precision, 91.8% accuracy, and 93.2% retrieval using the data collection. These efficiency metric levels are considerably higher than those used in any of the state-of-the-art CNN versions.

Range-Wide Snow Leopard Phylogeography Supports Three Subspecies.

The snow leopard, Panthera uncia, is an elusive high-altitude specialist that inhabits vast, inaccessible habitat across Asia. We conducted the first range-wide genetic assessment of snow leopards based on noninvasive scat surveys. Thirty-three microsatellites were genotyped and a total of 683 bp of mitochondrial DNA sequenced in 70 individuals. Snow leopards exhibited low genetic diversity at microsatellites (AN = 5.8, HO = 0.433, HE = 0.568), virtually no mtDNA variation, and underwent a bottleneck in the Holocene (∼8000 years ago) coinciding with increased temperatures, precipitation, and upward treeline shift in the Tibetan Plateau. Multiple analyses supported 3 primary genetic clusters: (1) Northern (the Altai region), (2) Central (core Himalaya and Tibetan Plateau), and (3) Western (Tian Shan, Pamir, trans-Himalaya regions). Accordingly, we recognize 3 subspecies, Panthera uncia irbis (Northern group), Panthera uncia uncia (Western group), and Panthera uncia uncioides (Central group) based upon genetic distinctness, low levels of admixture, unambiguous population assignment, and geographic separation. The patterns of variation were consistent with desert-basin "barrier effects" of the Gobi isolating the northern subspecies (Mongolia), and the trans-Himalaya dividing the central (Qinghai, Tibet, Bhutan, and Nepal) and western subspecies (India, Pakistan, Tajikistan, and Kyrgyzstan). Hierarchical Bayesian clustering analysis revealed additional subdivision into a minimum of 6 proposed management units: western Mongolia, southern Mongolia, Tian Shan, Pamir-Himalaya, Tibet-Himalaya, and Qinghai, with spatial autocorrelation suggesting potential connectivity by dispersing individuals up to ∼400 km. We provide a foundation for global conservation of snow leopard subspecies, and set the stage for in-depth landscape genetics and genomic studies.

Enhanced Living by Assessing Voice Pathology Using a Co-Occurrence Matrix.

A large number of the population around the world suffers from various disabilities. Disabilities affect not only children but also adults of different professions. Smart technology can assist the disabled population and lead to a comfortable life in an enhanced living environment (ELE). In this paper, we propose an effective voice pathology assessment system that works in a smart home framework. The proposed system takes input from various sensors, and processes the acquired voice signals and electroglottography (EGG) signals. Co-occurrence matrices in different directions and neighborhoods from the spectrograms of these signals were obtained. Several features such as energy, entropy, contrast, and homogeneity from these matrices were calculated and fed into a Gaussian mixture model-based classifier. Experiments were performed with a publicly available database, namely, the Saarbrucken voice database. The results demonstrate the feasibility of the proposed system in light of its high accuracy and speed. The proposed system can be extended to assess other disabilities in an ELE.

Detection of Voice Pathology using Fractal Dimension in a Multiresolution Analysis of Normal and Disordered Speech Signals.

Voice disorders are associated with irregular vibrations of vocal folds. Based on the source filter theory of speech production, these irregular vibrations can be detected in a non-invasive way by analyzing the speech signal. In this paper we present a multiband approach for the detection of voice disorders given that the voice source generally interacts with the vocal tract in a non-linear way. In normal phonation, and assuming sustained phonation of a vowel, the lower frequencies of speech are heavily source dependent due to the low frequency glottal formant, while the higher frequencies are less dependent on the source signal. During abnormal phonation, this is still a valid, but turbulent noise of source, because of the irregular vibration, affects also higher frequencies. Motivated by such a model, we suggest a multiband approach based on a three-level discrete wavelet transformation (DWT) and in each band the fractal dimension (FD) of the estimated power spectrum is estimated. The experiments suggest that frequency band 1-1562 Hz, lower frequencies after level 3, exhibits a significant difference in the spectrum of a normal and pathological subject. With this band, a detection rate of 91.28 % is obtained with one feature, and the obtained result is higher than all other frequency bands. Moreover, an accuracy of 92.45 % and an area under receiver operating characteristic curve (AUC) of 95.06 % is acquired when the FD of all levels is fused. Likewise, when the FD of all levels is combined with 22 Multi-Dimensional Voice Program (MDVP) parameters, an improvement of 2.26 % in accuracy and 1.45 % in AUC is observed.

GBERT: A hybrid deep learning model based on GPT-BERT for fake news detection.

The digital era has expanded social exposure with easy internet access for mobile users, allowing for global communication. Now, people can get to know what is going on around the globe with just a click; however, this has also resulted in the issue of fake news. Fake news is content that pretends to be true but is actually false and is disseminated to defraud. Fake news poses a threat to harmony, politics, the economy, and public opinion. As a result, bogus news detection has become an emerging research domain to identify a given piece of text as genuine or fraudulent. In this paper, a new framework called Generative Bidirectional Encoder Representations from Transformers (GBERT) is proposed that leverages a combination of Generative pre-trained transformer (GPT) and Bidirectional Encoder Representations from Transformers (BERT) and addresses the fake news classification problem. This framework combines the best features of both cutting-edge techniques-BERT's deep contextual understanding and the generative capabilities of GPT-to create a comprehensive representation of a given text. Both GPT and BERT are fine-tuned on two real-world benchmark corpora and have attained 95.30 % accuracy, 95.13 % precision, 97.35 % sensitivity, and a 96.23 % F1 score. The statistical test results indicate the effectiveness of the fine-tuned framework for fake news detection and suggest that it can be a promising approach for eradicating this global issue of fake news in the digital landscape.

Internet of medical things and blockchain-enabled patient-centric agent through SDN for remote patient monitoring in 5G network.

During the COVID-19 pandemic, there has been a significant increase in the use of internet resources for accessing medical care, resulting in the development and advancement of the Internet of Medical Things (IoMT). This technology utilizes a range of medical equipment and testing software to broadcast patient results over the internet, hence enabling the provision of remote healthcare services. Nevertheless, the preservation of privacy and security in the realm of online communication continues to provide a significant and pressing obstacle. Blockchain technology has shown the potential to mitigate security apprehensions across several sectors, such as the healthcare industry. Recent advancements in research have included intelligent agents in patient monitoring systems by integrating blockchain technology. However, the conventional network configuration of the agent and blockchain introduces a level of complexity. In order to address this disparity, we present a proposed architectural framework that combines software defined networking (SDN) with Blockchain technology. This framework is specially tailored for the purpose of facilitating remote patient monitoring systems within the context of a 5G environment. The architectural design contains a patient-centric agent (PCA) inside the SDN control plane for the purpose of managing user data on behalf of the patients. The appropriate handling of patient data is ensured by the PCA via the provision of essential instructions to the forwarding devices. The suggested model is assessed using hyperledger fabric on docker-engine, and its performance is compared to that of current models in fifth generation (5G) networks. The performance of our suggested model surpasses current methodologies, as shown by our extensive study including factors such as throughput, dependability, communication overhead, and packet error rate.

Innovative aspects and applications of single cell technology for different diseases.

Recent developments in single-cell technologies have provided valuable insights from cancer genomics to complex microbial communities. Single-cell technologies including the RNA-seq, next-generation sequencing (NGS), epigenomics, genomics, and transcriptomics can be used to uncover the single cell nature and molecular characterization of individual cells. These technologies also reveal the cellular transition states, evolutionary relationships between genes, the complex structure of single-cell populations, cell-to-cell interaction leading to biological discoveries and more reliable than traditional bulk technologies. These technologies are becoming the first choice for the early detection of inflammatory biomarkers affecting the proliferation and progression of tumor cells in the tumor microenvironment and improving the clinical efficacy of patients undergoing immunotherapy. These technologies also hold a central position in the detection of checkpoint inhibitors and thus determining the signaling pathways evoked by tumor invasion. This review addressed the emerging approaches of single cell-based technologies in cancer immunotherapies and different human diseases at cellular and molecular levels and the emerging role of sequencing technologies leading to drug discovery. Advancements in these technologies paved for discovering novel diagnostic markers for better understanding the pathological and biochemical mechanisms also for controlling the rate of different diseases.

Abatement of Aerosols by Ionic Wind Extracted From Dielectric Barrier Discharge Plasma.

Lahore (Pakistan), being an industrial city, has high emission of aerosols that affects and contaminates the air quality. Therefore, the abatement/inactivation of aerosols is necessary to restrict their infectious activities. In this project, ionic wind isolated from dielectric barrier discharge plasma (DBD plasma) has been utilized to abate the aerosols trapped in the Surgical Mask and KN95 Respirator. To infer the chemical and elemental detection of ambient aerosols, FTIR and LIBS have been employed. "From the results, it is noteworthy that abatement/removal of aerosols has been successfully carried out by the ionic wind irradiation and highlights the potential of DBD plasma technology in removing the aerosols pollution."