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1.
Cureus ; 15(8): e42884, 2023 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-37664348

RESUMO

Traumatic posterior chamber intraocular lens (PC-IOL) extrusion via a self-sealing scleral tunnel, created for manual small-incision cataract surgery (MSICS), is a rare occurrence that has never been reported before. Usually, the PC-IOL protrudes through a ruptured cornea or falls back into the vitreous after blunt trauma. Here, we present a case of PC-IOL extrusion along the uveal tissue through the scleral tunnel in an 80-year-old woman with a history of MSICS who fell and hit her right eye on the stairs, resulting in sudden and painful loss of vision in the same eye. The IOL, along with necrotic uveal tissue, was removed from the subconjunctival space, and the ruptured scleral tunnel was sutured. After initial management, her best-corrected visual acuity (BCVA) was 6/36 with aphakic spectacle correction. The patient was advised to undergo secondary scleral fixation of the intraocular lens. The scleral tunnel made in MSICS is a potentially weak area, and the PC-IOL can come out through it. Therefore, suturing the scleral tunnel with a non-absorbable nylon 10-0 suture should be considered during MSICS. This provides additional support to the weakened scleral wall.

2.
Cureus ; 15(9): e45371, 2023 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-37849604

RESUMO

INTRODUCTION: The clinical use of intravitreal bevacizumab (IVB), a recombinant humanized monoclonal antibody that functions as an anti-vascular endothelial growth factor (anti-VEGF), has recently increased in patients with retinal ischemic diseases such as proliferative diabetic retinopathy (PDR). The short-term and long-term complications associated with this procedure have not been well established. We aimed to study the possible short-term complication of intraocular pressure (IOP) fluctuations shortly after IVB injection in patients with PDR. MATERIALS AND METHODS: A prospective case series of diabetic patients with PDR who underwent IVB injection was performed in the Department of Ophthalmology, Medical Teaching Institution, Khyber Teaching Hospital, Peshawar, Pakistan, from November 1, 2020, to May 1, 2021. The total number of PDR patients of both sexes included in the study was 101. A slit lamp examination was performed, and IOP readings were recorded before and 30 min after IVB injection using Goldmann applanation tonometry (GAT). IBM Statistical Package for the Social Sciences version 22 for Windows was used to analyze the data. Safety of the procedure, defined as IOP ≤20 mmHg 30 min after IVB injection, was determined and stratified according to sex, age, duration of diabetes, and baseline IOP. A post-stratification chi-square test was applied, and a p-value <0.05 was taken as statistically significant. RESULTS: In this study, 60.4% of the participants were male and 39.6% were female. The age of the patients ranged from 30 to 75 years, with a mean age of 55.66±6.37 years. The mean duration of diabetes among the participants was 7.73±2.94 years and the mean baseline IOP was 15.40±1.77 mmHg. Safety (IOP ≤20 mmHg 30 min after IVB injection) was observed in 90.1% of the patients. CONCLUSION: IVB injections are safe for use in patients with PDR in terms of immediate IOP changes. However, patients with higher baseline IOP (>15 mmHg) are more likely to develop increased IOP post-procedure and prophylaxis may be prudent in such cases.

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