Detalhe da pesquisa
1.
The Prohibitin-Binding Compound Fluorizoline Activates the Integrated Stress Response through the eIF2α Kinase HRI.
Int J Mol Sci;
24(9)2023 Apr 29.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37175767
2.
Fluorizoline-induced apoptosis requires prohibitins in nematodes and human cells.
Apoptosis;
26(1-2): 83-95, 2021 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33387147
3.
Activation of the Integrated Stress Response and ER Stress Protect from Fluorizoline-Induced Apoptosis in HEK293T and U2OS Cell Lines.
Int J Mol Sci;
22(11)2021 Jun 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34204139
4.
The prohibitin-binding compound fluorizoline induces apoptosis in chronic lymphocytic leukemia cells through the upregulation of NOXA and synergizes with ibrutinib, 5-aminoimidazole-4-carboxamide riboside or venetoclax.
Haematologica;
102(9): 1587-1593, 2017 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28619845
5.
The prohibitin-binding compound fluorizoline induces the pro-inflammatory cytokines interleukin-8 and interleukin-6 through the activation of JNK and p38 MAP kinases.
Biochem Pharmacol;
218: 115860, 2023 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37884196
6.
The prohibitin-binding compound fluorizoline inhibits mitophagy in cancer cells.
Oncogenesis;
10(9): 64, 2021 Sep 27.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34580273
7.
NOXA upregulation by the prohibitin-binding compound fluorizoline is transcriptionally regulated by integrated stress response-induced ATF3 and ATF4.
FEBS J;
288(4): 1271-1285, 2021 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32648994
8.
The BCL-2 family members NOXA and BIM mediate fluorizoline-induced apoptosis in multiple myeloma cells.
Biochem Pharmacol;
180: 114198, 2020 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32798467
9.
Targeting prohibitins induces apoptosis in acute myeloid leukemia cells.
Oncotarget;
7(40): 64987-65000, 2016 Oct 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27542247
10.
A novel prohibitin-binding compound induces the mitochondrial apoptotic pathway through NOXA and BIM upregulation.
Oncotarget;
6(39): 41750-65, 2015 Dec 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26497683