Detalhe da pesquisa
1.
Structure-activity relationship study, target identification, and pharmacological characterization of a small molecular IL-12/23 inhibitor, APY0201.
Bioorg Med Chem;
22(11): 3021-9, 2014 Jun 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24767819
2.
RCAI-61 and related 6'-modified analogs of KRN7000: their synthesis and bioactivity for mouse lymphocytes to produce interferon-γ in vivo.
Bioorg Med Chem;
21(11): 3066-79, 2013 Jun 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23602521
3.
Pyridone 6, a pan-JAK inhibitor, ameliorates allergic skin inflammation of NC/Nga mice via suppression of Th2 and enhancement of Th17.
J Immunol;
187(9): 4611-20, 2011 Nov 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21957150
4.
Induction of Th1-biased cytokine production by alpha-carba-GalCer, a neoglycolipid ligand for NKT cells.
Int Immunol;
22(4): 319-28, 2010 Apr.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20181652
5.
A major lipid raft protein raftlin modulates T cell receptor signaling and enhances th17-mediated autoimmune responses.
J Immunol;
182(10): 5929-37, 2009 May 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19414744
6.
SOCS3 in T and NKT cells negatively regulates cytokine production and ameliorates ConA-induced hepatitis.
J Immunol;
183(11): 7047-53, 2009 Dec 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19915050
7.
PDC-TREM, a plasmacytoid dendritic cell-specific receptor, is responsible for augmented production of type I interferon.
Proc Natl Acad Sci U S A;
105(8): 2993-8, 2008 Feb 26.
Artigo
em Inglês
| MEDLINE
| ID: mdl-18287072
8.
Gfi1 negatively regulates T(h)17 differentiation by inhibiting RORgammat activity.
Int Immunol;
21(7): 881-9, 2009 Jul.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19505891
9.
Sprouty4 deficiency potentiates Ras-independent angiogenic signals and tumor growth.
Cancer Sci;
100(9): 1648-54, 2009 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19493272
10.
The mTOR pathway is highly activated in diabetic nephropathy and rapamycin has a strong therapeutic potential.
Biochem Biophys Res Commun;
384(4): 471-5, 2009 Jul 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19422788
11.
A simple synthesis of four stereoisomers of roseoside and their inhibitory activity on leukotriene release from mice bone marrow-derived cultured mast cells.
Bioorg Med Chem;
17(1): 189-94, 2009 Jan 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19026550
12.
RCAI-37, 56, 59, 60, 92, 101, and 102, cyclitol and carbasugar analogs of KRN7000: their synthesis and bioactivity for mouse lymphocytes to produce Th1-biased cytokines.
Bioorg Med Chem;
17(17): 6360-73, 2009 Sep 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19656685
13.
RCAI-17, 22, 24-26, 29, 31, 34-36, 38-40, and 88, the analogs of KRN7000 with a sulfonamide linkage: their synthesis and bioactivity for mouse natural killer T cells to produce Th2-biased cytokines.
Bioorg Med Chem;
16(19): 8896-906, 2008 Oct 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-18790646
14.
RCAI-8, 9, 18, 19, and 49-52, conformationally restricted analogues of KRN7000 with an azetidine or a pyrrolidine ring: Their synthesis and bioactivity for mouse natural killer T cells to produce cytokines.
Bioorg Med Chem;
16(2): 950-64, 2008 Jan 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-17950609
15.
Characterization of galectin-9-induced death of Jurkat T cells.
J Biochem;
141(2): 157-72, 2007 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-17167046
16.
[Galectin-9 induces maturation of human monocyte-derived dendritic cells].
Nihon Rinsho Meneki Gakkai Kaishi;
28(6): 381-8, 2005 Dec.
Artigo
em Japonês
| MEDLINE
| ID: mdl-16394641
17.
Synthesis and biological activity of ester and ether analogues of alpha-galactosylceramide (KRN7000).
Carbohydr Res;
345(12): 1663-84, 2010 Aug 16.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20591421
18.
Pivotal role of cerebral interleukin-17-producing gammadeltaT cells in the delayed phase of ischemic brain injury.
Nat Med;
15(8): 946-50, 2009 Aug.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19648929
19.
Methods for detection, isolation and culture of mouse and human invariant NKT cells.
Nat Protoc;
3(1): 70-8, 2008.
Artigo
em Inglês
| MEDLINE
| ID: mdl-18193023
20.
A novel subset of mouse NKT cells bearing the IL-17 receptor B responds to IL-25 and contributes to airway hyperreactivity.
J Exp Med;
205(12): 2727-33, 2008 Nov 24.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19015310