Detalhe da pesquisa
1.
Synthesis of 2-Substituted Indoles via Migration Reaction of 3-Substituted Indoles with Triflic Acid.
Chem Pharm Bull (Tokyo);
72(3): 336-339, 2024.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38522900
2.
Fluorescent Rotary Switches: Four- vs Three-Substituted Phthalimide Boron Difluoride Schiff Base Complexes.
J Org Chem;
88(24): 17206-17214, 2023 Dec 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38099317
3.
Design and synthesis of 6-methylpyridin-2-one derivatives as novel and potent GluN2A positive allosteric modulators for the treatment of cognitive impairment.
Bioorg Med Chem;
79: 117150, 2023 02 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36640594
4.
Solvent-Triggered Long-Range Proton Transport in 7-Hydroxyquinoline Using a Sulfonamide Transporter Group.
J Org Chem;
87(10): 6794-6806, 2022 05 20.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35512011
5.
Discovery of Pyrazolo[1,5-a]pyrazin-4-ones as Potent and Brain Penetrant GluN2A-Selective Positive Allosteric Modulators Reducing AMPA Receptor Binding Activity.
Bioorg Med Chem;
56: 116576, 2022 02 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35051811
6.
Neurological sedative indicators during general anesthesia with remimazolam.
J Anesth;
36(2): 194-200, 2022 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34999964
7.
Acylhydrazone Subunits as a Proton Cargo Delivery System in 7-Hydroxyquinoline.
Chemistry;
27(45): 11559-11566, 2021 Aug 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34137094
8.
Asymmetric Conjugate Addition of Phosphonates to Enones Using Cinchona-Diaminomethylenemalononitrile Organocatalysts.
J Org Chem;
85(5): 3872-3878, 2020 03 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31986038
9.
Clinical improvement in a patient with severe coronavirus disease 2019 after administration of hydroxychloroquine and continuous hemodiafiltlation with nafamostat mesylate.
J Infect Chemother;
26(12): 1319-1323, 2020 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32893123
10.
De Novo Mutations in PDE10A Cause Childhood-Onset Chorea with Bilateral Striatal Lesions.
Am J Hum Genet;
98(4): 763-71, 2016 Apr 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27058447
11.
A homozygous loss-of-function mutation in PDE2A associated to early-onset hereditary chorea.
Mov Disord;
33(3): 482-488, 2018 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29392776
12.
Asymmetric Conjugate Addition of α-Cyanoketones to Enones Using Diaminomethylenemalononitrile Organocatalyst.
J Org Chem;
83(4): 2402-2408, 2018 02 16.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29333849
13.
Stereoselective conjugate addition of ketones to alkylidene malonates using thiourea-sulfonamide organocatalyst.
Chirality;
30(11): 1215-1224, 2018 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30211959
14.
Asymmetric Conjugate Addition of Nitroalkanes to Enones Using a Sulfonamide-Thiourea Organocatalyst.
J Org Chem;
82(13): 6986-6991, 2017 07 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28605586
15.
Squaramide-Sulfonamide Organocatalyst for Asymmetric Direct Vinylogous Aldol Reactions.
J Org Chem;
82(9): 4661-4667, 2017 05 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28394134
16.
Asymmetric Conjugate Additions of Carbonyl Compounds to Nitroalkenes under Solvent-Free Conditions Using Fluorous Diaminomethylenemalononitrile Organocatalyst.
Chem Pharm Bull (Tokyo);
65(12): 1185-1190, 2017.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29199223
17.
Design and synthesis of potent and selective pyridazin-4(1H)-one-based PDE10A inhibitors interacting with Tyr683 in the PDE10A selectivity pocket.
Bioorg Med Chem;
24(16): 3447-55, 2016 08 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27301679
18.
Asymmetric Chlorination of ß-Keto Esters Using Diaminomethylenemalononitrile Organocatalyst.
Chem Pharm Bull (Tokyo);
64(12): 1781-1784, 2016.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27904086
19.
Design and synthesis of a novel 2-oxindole scaffold as a highly potent and brain-penetrant phosphodiesterase 10A inhibitor.
Bioorg Med Chem;
23(22): 7138-49, 2015 Nov 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26494583
20.
Development of a series of novel carbon-11 labeled PDE10A inhibitors.
J Labelled Comp Radiopharm;
58(5): 202-8, 2015 May 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25891816