Detalhe da pesquisa
1.
Prolyl isomerase Pin1 in skeletal muscles contributes to systemic energy metabolism and exercise capacity through regulating SERCA activity.
Biochem Biophys Res Commun;
715: 150001, 2024 Jun 30.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38676996
2.
Prolyl isomerase Pin1 promotes extracellular matrix production in hepatic stellate cells through regulating formation of the Smad3-TAZ complex.
Exp Cell Res;
425(2): 113544, 2023 04 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36906101
3.
miR-582-5p targets Skp1 and regulates NF-κB signaling-mediated inflammation.
Arch Biochem Biophys;
734: 109501, 2023 01 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36592647
4.
Hepatic Pin1 Expression, Particularly in Nuclei, Is Increased in NASH Patients in Accordance with Evidence of the Role of Pin1 in Lipid Accumulation Shown in Hepatoma Cell Lines.
Int J Mol Sci;
24(10)2023 May 16.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37240193
5.
Auraptene Enhances AMP-Activated Protein Kinase Phosphorylation and Thereby Inhibits the Proliferation, Migration and Expression of Androgen Receptors and Prostate-Specific Antigens in Prostate Cancer Cells.
Int J Mol Sci;
24(21)2023 Nov 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37958994
6.
Carnosic Acid and Carnosol Activate AMPK, Suppress Expressions of Gluconeogenic and Lipogenic Genes, and Inhibit Proliferation of HepG2 Cells.
Int J Mol Sci;
22(8)2021 Apr 14.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33919842
7.
Biventricular Thrombi Associated with Cardiac Systolic Dysfunction and Disseminated Intravascular Coagulation from Heat Stroke.
Int Heart J;
62(3): 687-694, 2021 May 29.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33994503
8.
Xanthine Oxidase Inhibitor Febuxostat Exerts an Anti-Inflammatory Action and Protects against Diabetic Nephropathy Development in KK-Ay Obese Diabetic Mice.
Int J Mol Sci;
20(19)2019 Sep 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31546603
9.
The prolyl isomerase Pin1 increases ß-cell proliferation and enhances insulin secretion.
J Biol Chem;
292(28): 11886-11895, 2017 07 14.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28566287
10.
Protective Effect of Sex Hormone-Binding Globulin against Metabolic Syndrome: In Vitro Evidence Showing Anti-Inflammatory and Lipolytic Effects on Adipocytes and Macrophages.
Mediators Inflamm;
2018: 3062319, 2018.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30046278
11.
Roles of Gut-Derived Secretory Factors in the Pathogenesis of Non-Alcoholic Fatty Liver Disease and Their Possible Clinical Applications.
Int J Mol Sci;
19(10)2018 Oct 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30297626
12.
The Xanthine Oxidase Inhibitor Febuxostat Suppresses the Progression of IgA Nephropathy, Possibly via Its Anti-Inflammatory and Anti-Fibrotic Effects in the gddY Mouse Model.
Int J Mol Sci;
19(12)2018 Dec 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30544662
13.
USP15 attenuates IGF-I signaling by antagonizing Nedd4-induced IRS-2 ubiquitination.
Biochem Biophys Res Commun;
484(3): 522-528, 2017 03 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28126338
14.
Reduced SHARPIN and LUBAC Formation May Contribute to CCl4- or Acetaminophen-Induced Liver Cirrhosis in Mice.
Int J Mol Sci;
18(2)2017 Feb 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28165393
15.
The SGLT2 Inhibitor Luseogliflozin Rapidly Normalizes Aortic mRNA Levels of Inflammation-Related but Not Lipid-Metabolism-Related Genes and Suppresses Atherosclerosis in Diabetic ApoE KO Mice.
Int J Mol Sci;
18(8)2017 Aug 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28777298
16.
Prolyl isomerase Pin1 negatively regulates AMP-activated protein kinase (AMPK) by associating with the CBS domain in the γ subunit.
J Biol Chem;
290(40): 24255-66, 2015 Oct 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26276391
17.
Role of Uric Acid Metabolism-Related Inflammation in the Pathogenesis of Metabolic Syndrome Components Such as Atherosclerosis and Nonalcoholic Steatohepatitis.
Mediators Inflamm;
2016: 8603164, 2016.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28070145
18.
Physiological and Pathogenic Roles of Prolyl Isomerase Pin1 in Metabolic Regulations via Multiple Signal Transduction Pathway Modulations.
Int J Mol Sci;
17(9)2016 Sep 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27618008
19.
DPP-IV inhibitor anagliptin exerts anti-inflammatory effects on macrophages, adipocytes, and mouse livers by suppressing NF-κB activation.
Am J Physiol Endocrinol Metab;
309(3): E214-23, 2015 Aug 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26015438
20.
The xanthine oxidase inhibitor febuxostat suppresses development of nonalcoholic steatohepatitis in a rodent model.
Am J Physiol Gastrointest Liver Physiol;
309(1): G42-51, 2015 Jul 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25999428