Detalhe da pesquisa
1.
Medin co-aggregates with vascular amyloid-ß in Alzheimer's disease.
Nature;
612(7938): 123-131, 2022 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36385530
2.
Discriminating α-synuclein strains in Parkinson's disease and multiple system atrophy.
Nature;
578(7794): 273-277, 2020 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32025029
3.
Neuronal Ndst1 depletion accelerates prion protein clearance and slows neurodegeneration in prion infection.
PLoS Pathog;
19(9): e1011487, 2023 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37747931
4.
Two structurally defined Aß polymorphs promote different pathological changes in susceptible mice.
EMBO Rep;
24(8): e57003, 2023 08 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37424505
5.
A Novel Drosophila Model of Alzheimer's Disease to Study Aß Proteotoxicity in the Digestive Tract.
Int J Mol Sci;
25(4)2024 Feb 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38396782
6.
Thiophene-Based Ligands: Design, Synthesis and Their Utilization for Optical Assignment of Polymorphic-Disease-Associated Protein Aggregates.
Chembiochem;
24(11): e202300044, 2023 06 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36891883
7.
Mutation ∆K281 in MAPT causes Pick's disease.
Acta Neuropathol;
146(2): 211-226, 2023 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37351604
8.
Thiophene-Based Ligands for Histological Multiplex Spectral Detection of Distinct Protein Aggregates in Alzheimer's Disease.
Chemistry;
29(21): e202203568, 2023 Apr 13.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36645413
9.
Synapsin III gene silencing redeems alpha-synuclein transgenic mice from Parkinson's disease-like phenotype.
Mol Ther;
30(4): 1465-1483, 2022 04 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35038583
10.
Distinct Heterocyclic Moieties Govern the Selectivity of Thiophene-Vinylene-Based Ligands Towards Aß or Tau Pathology in Alzheime's Disease.
European J Org Chem;
26(41)2023 Nov 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38585413
11.
Distinct conformers of amyloid beta accumulate in the neocortex of patients with rapidly progressive Alzheimer's disease.
J Biol Chem;
297(5): 101267, 2021 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34599965
12.
Structural Properties Dictating Selective Optotracer Detection of Staphylococcus aureus.
Chembiochem;
23(11): e202100684, 2022 06 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35298076
13.
Proteophenes - Amino Acid Functionalized Thiophene-based Fluorescent Ligands for Visualization of Protein Deposits in Tissue Sections with Alzheimer's Disease Pathology.
Chemistry;
28(62): e202201557, 2022 Nov 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35950816
14.
Early detection of prion protein aggregation with a fluorescent pentameric oligothiophene probe using spectral confocal microscopy.
J Neurochem;
156(6): 1033-1048, 2021 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32799317
15.
Deciphering the Electronic Transitions of Thiophene-Based Donor-Acceptor-Donor Pentameric Ligands Utilized for Multimodal Fluorescence Microscopy of Protein Aggregates.
Chemphyschem;
22(3): 323-335, 2021 02 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33219724
16.
Pyroglutamation of amyloid-ßx-42 (Aßx-42) followed by Aß1-40 deposition underlies plaque polymorphism in progressing Alzheimer's disease pathology.
J Biol Chem;
294(17): 6719-6732, 2019 04 26.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30814252
17.
Shortening heparan sulfate chains prolongs survival and reduces parenchymal plaques in prion disease caused by mobile, ADAM10-cleaved prions.
Acta Neuropathol;
139(3): 527-546, 2020 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31673874
18.
Synthesis and Characterization of Thiophene-based Donor-Acceptor-Donor Heptameric Ligands for Spectral Assignment of Polymorphic Amyloid-ß Deposits.
Chemistry;
26(33): 7425-7432, 2020 Jun 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32022335
19.
In vivo polymerization and manufacturing of wires and supercapacitors in plants.
Proc Natl Acad Sci U S A;
114(11): 2807-2812, 2017 03 14.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28242683
20.
Amyloid polymorphisms constitute distinct clouds of conformational variants in different etiological subtypes of Alzheimer's disease.
Proc Natl Acad Sci U S A;
114(49): 13018-13023, 2017 12 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29158413