Detalhe da pesquisa
1.
Syntheses and antimicrobial activities of ogipeptin derivatives.
Bioorg Med Chem Lett;
42: 128093, 2021 06 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33964447
2.
Practical one-step glucuronidation via biotransformation.
Bioorg Med Chem Lett;
29(2): 199-203, 2019 01 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30551902
3.
Synthesis and evaluation of thiomannosides, potent and orally active FimH inhibitors.
Bioorg Med Chem Lett;
28(17): 2993-2997, 2018 09 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30017316
4.
Corrigendum to "Syntheses and antimicrobial activities of ogipeptin derivatives" [Bioorg. Med. Chem. Lett. 42 (2021) 128093].
Bioorg Med Chem Lett;
47: 128228, 2021 Sep 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34192636
5.
Synthesis and SAR studies of benzyl ether derivatives as potent orally active S1P1 agonists.
Bioorg Med Chem;
22(15): 4246-56, 2014 Aug 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24909680
6.
[Looking Back on My Life in Research over more than 40 Years].
Yakugaku Zasshi;
144(1): 71-85, 2024.
Artigo
em Japonês
| MEDLINE
| ID: mdl-38171799
7.
Synthesis and optimization of novel (3S,5R)-5-(2,2-dimethyl-5-oxo-4-phenylpiperazin-1-yl)piperidine-3-carboxamides as orally active renin inhibitors.
Bioorg Med Chem;
21(18): 5907-22, 2013 Sep 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23886807
8.
Lead optimization of 5-amino-6-(2,2-dimethyl-5-oxo-4-phenylpiperazin-1-yl)-4-hydroxyhexanamides to reduce a cardiac safety issue: discovery of DS-8108b, an orally active renin inhibitor.
Bioorg Med Chem;
21(11): 3175-96, 2013 Jun 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23598247
9.
Design and optimization of novel (2S,4S,5S)-5-amino-6-(2,2-dimethyl-5-oxo-4-phenylpiperazin-1-yl)-4-hydroxy-2-isopropylhexanamides as renin inhibitors.
Bioorg Med Chem Lett;
22(14): 4561-6, 2012 Jul 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22726934
10.
Design and discovery of new (3S,5R)-5-[4-(2-chlorophenyl)-2,2-dimethyl-5-oxopiperazin-1-yl]piperidine-3-carboxamides as potent renin inhibitors.
Bioorg Med Chem Lett;
22(24): 7677-82, 2012 Dec 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23122821
11.
Discovery of CS-2100, a potent, orally active and S1P3-sparing S1P1 agonist.
Bioorg Med Chem Lett;
22(4): 1788-92, 2012 Feb 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22264485
12.
Synthesis and SAR of 1,3-thiazolyl thiophene and pyridine derivatives as potent, orally active and S1P3-sparing S1P1 agonists.
Bioorg Med Chem Lett;
22(9): 3083-8, 2012 May 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22487179
13.
Total Synthesis and Structural Elucidation of Ogipeptins.
Org Lett;
24(27): 4935-4938, 2022 07 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35796660
14.
Structure-based drug design of tricyclic 8H-indeno[1,2-d][1,3]thiazoles as potent FBPase inhibitors.
Bioorg Med Chem Lett;
20(3): 1004-7, 2010 Feb 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20045638
15.
A prodrug approach towards the development of tricyclic-based FBPase inhibitors.
Bioorg Med Chem Lett;
20(9): 2938-41, 2010 May 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20359891
16.
Discovery of potent and orally active tricyclic-based FBPase inhibitors.
Bioorg Med Chem;
18(14): 5346-51, 2010 Jul 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20542703
17.
Synthesis, SAR, and X-ray structure of tricyclic compounds as potent FBPase inhibitors.
Bioorg Med Chem Lett;
19(20): 5909-12, 2009 Oct 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19762234
18.
Discovery of DS-8108b, a Novel Orally Bioavailable Renin Inhibitor.
ACS Med Chem Lett;
3(9): 754-8, 2012 Sep 13.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24900544
19.
Synthesis and evaluation of CS-2100, a potent, orally active and S1P(3)- sparing S1P(1) agonist.
Eur J Med Chem;
51: 92-8, 2012 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22405291
20.
Discovery of CS-0777: A Potent, Selective, and Orally Active S1P1 Agonist.
ACS Med Chem Lett;
2(5): 368-72, 2011 May 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24900318