Detalhe da pesquisa
1.
Eukaryotic RNA-guided endonucleases evolved from a unique clade of bacterial enzymes.
Nucleic Acids Res;
51(22): 12414-12427, 2023 Dec 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37971304
2.
Discovery and Validation of the Binding Poses of Allosteric Fragment Hits to Protein Tyrosine Phosphatase 1b: From Molecular Dynamics Simulations to X-ray Crystallography.
J Chem Inf Model;
63(9): 2644-2650, 2023 05 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37086179
3.
A Deep-Learning View of Chemical Space Designed to Facilitate Drug Discovery.
J Chem Inf Model;
60(10): 4487-4496, 2020 10 26.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32697578
4.
OSPREY 3.0: Open-source protein redesign for you, with powerful new features.
J Comput Chem;
39(30): 2494-2507, 2018 11 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30368845
5.
RNA language models predict mutations that improve RNA function.
bioRxiv;
2024 Apr 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38617247
6.
A map of the rubisco biochemical landscape.
bioRxiv;
2024 Apr 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38645011
7.
Coherent Blending of Biophysics-Based Knowledge with Bayesian Neural Networks for Robust Protein Property Prediction.
ACS Synth Biol;
12(11): 3242-3251, 2023 Nov 17.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37888887
8.
Eukaryotic RNA-guided endonucleases evolved from a unique clade of bacterial enzymes.
bioRxiv;
2023 Aug 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37609353
9.
Identification of GDC-1971 (RLY-1971), a SHP2 Inhibitor Designed for the Treatment of Solid Tumors.
J Med Chem;
66(19): 13384-13399, 2023 Oct 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37774359
10.
Learning protein fitness models from evolutionary and assay-labeled data.
Nat Biotechnol;
40(7): 1114-1122, 2022 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35039677
11.
Epistatic Net allows the sparse spectral regularization of deep neural networks for inferring fitness functions.
Nat Commun;
12(1): 5225, 2021 09 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34471113
12.
XYZeq: Spatially resolved single-cell RNA sequencing reveals expression heterogeneity in the tumor microenvironment.
Sci Adv;
7(17)2021 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33883145
13.
Beyond medical pluralism: characterising health-care delivery of biomedicine and traditional medicine in rural Guatemala.
Glob Public Health;
13(4): 503-517, 2018 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27416306
14.
Algorithms for protein design.
Curr Opin Struct Biol;
39: 16-26, 2016 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27086078