Detalhe da pesquisa
1.
Structure-activity relationship around PI-2620 highlights the importance of the nitrogen atom position in the tricyclic core.
Bioorg Med Chem;
52: 116528, 2021 12 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34839158
2.
Discovery and preclinical characterization of [18F]PI-2620, a next-generation tau PET tracer for the assessment of tau pathology in Alzheimer's disease and other tauopathies.
Eur J Nucl Med Mol Imaging;
46(10): 2178-2189, 2019 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31264169
3.
CAR T Cells with Enhanced Sensitivity to B Cell Maturation Antigen for the Targeting of B Cell Non-Hodgkin's Lymphoma and Multiple Myeloma.
Mol Ther;
26(8): 1906-1920, 2018 08 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30078440
4.
PI-2620 Lead Optimization Highlights the Importance of Off-Target Assays to Develop a PET Tracer for the Detection of Pathological Aggregated Tau in Alzheimer's Disease and Other Tauopathies.
J Med Chem;
64(17): 12808-12830, 2021 09 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34455780
5.
Discovery of 2-(4-(2-fluoroethoxy)piperidin-1-yl)-9-methyl-9H-pyrrolo[2,3-b:4,5-c']dipyridine ([18F]PI-2014) as PET tracer for the detection of pathological aggregated tau in Alzheimer's disease and other tauopathies.
Eur J Med Chem;
204: 112615, 2020 Oct 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32771872
6.
18F-GP1, a Novel PET Tracer Designed for High-Sensitivity, Low-Background Detection of Thrombi.
J Nucl Med;
58(7): 1094-1099, 2017 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28302764
7.
Potent anti-tumor response by targeting B cell maturation antigen (BCMA) in a mouse model of multiple myeloma.
Mol Oncol;
9(7): 1348-58, 2015 Aug.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25953704
8.
Development of self-reactive germinal center B cells and plasma cells in autoimmune Fc gammaRIIB-deficient mice.
J Exp Med;
207(12): 2767-78, 2010 Nov 22.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21078890