Detalhe da pesquisa
1.
Advances in hereditary leiomyomatosis and renal cell carcinoma (HLRCC) research.
Semin Cancer Biol;
61: 158-166, 2020 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31689495
2.
RPA1 binding to NRF2 switches ARE-dependent transcriptional activation to ARE-NRE-dependent repression.
Proc Natl Acad Sci U S A;
115(44): E10352-E10361, 2018 10 30.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30309964
3.
Differential and overlapping targets of the transcriptional regulators NRF1, NRF2, and NRF3 in human cells.
J Biol Chem;
294(48): 18131-18149, 2019 11 29.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31628195
4.
Kelch-like ECH-associated protein 1 (KEAP1) differentially regulates nuclear factor erythroid-2-related factors 1 and 2 (NRF1 and NRF2).
J Biol Chem;
293(6): 2029-2040, 2018 02 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29255090
5.
Fumarate hydratase inactivation in hereditary leiomyomatosis and renal cell cancer is synthetic lethal with ferroptosis induction.
Cancer Sci;
109(9): 2757-2766, 2018 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29917289
6.
The effects of NRF2 modulation on the initiation and progression of chemically and genetically induced lung cancer.
Mol Carcinog;
57(2): 182-192, 2018 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28976703
7.
Brusatol overcomes chemoresistance through inhibition of protein translation.
Mol Carcinog;
56(5): 1493-1500, 2017 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28019675
8.
Sustained NRF2 activation in hereditary leiomyomatosis and renal cell cancer (HLRCC) and in hereditary tyrosinemia type 1 (HT1).
Biochem Soc Trans;
43(4): 650-6, 2015 Aug.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26551707
9.
Association of Metal Cations with the Anti-PF4/Heparin Antibody Response in Heparin-Induced Thrombocytopenia.
Res Sq;
2024 May 16.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38798628
10.
Decreased autophagosome biogenesis, reduced NRF2, and enhanced ferroptotic cell death are underlying molecular mechanisms of non-alcoholic fatty liver disease.
Redox Biol;
59: 102570, 2023 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36495698
11.
The NRF2-p97-NRF2 negative feedback loop.
Redox Biol;
65: 102839, 2023 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37573837
12.
NRF2 controls iron homeostasis and ferroptosis through HERC2 and VAMP8.
Sci Adv;
9(5): eade9585, 2023 02 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36724221
13.
Fumarate hydratase inactivation in renal tumors: HIF1α, NRF2, and "cryptic targets" of transcription factors.
Chin J Cancer;
31(9): 413-20, 2012 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22776233
14.
Aroylhydrazone Glycoconjugate Prochelators Exploit Glucose Transporter 1 (GLUT1) to Target Iron in Cancer Cells.
ACS Med Chem Lett;
13(9): 1452-1458, 2022 Sep 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36105345
15.
Cyst(e)inase-Rapamycin Combination Induces Ferroptosis in Both In Vitro and In Vivo Models of Hereditary Leiomyomatosis and Renal Cell Cancer.
Mol Cancer Ther;
21(3): 419-426, 2022 03 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35086957
16.
Targeted CUL4A inhibition synergizes with cisplatin to yield long-term survival in models of head and neck squamous cell carcinoma through a DDB2-mediated mechanism.
Cell Death Dis;
13(4): 350, 2022 04 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35428778
17.
CHML is an NRF2 target gene that regulates mTOR function.
Mol Oncol;
16(8): 1714-1727, 2022 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35184380
18.
Non-canonical NRF2 activation promotes a pro-diabetic shift in hepatic glucose metabolism.
Mol Metab;
51: 101243, 2021 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33933676
19.
The NRF2-LOC344887 signaling axis suppresses pulmonary fibrosis.
Redox Biol;
38: 101766, 2021 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33126057
20.
Iron control of erythroid microtubule cytoskeleton as a potential target in treatment of iron-restricted anemia.
Nat Commun;
12(1): 1645, 2021 03 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33712594