Detalhe da pesquisa
1.
Membrane Interaction Characteristics of the RTX Toxins and the Cholesterol-Dependence of Their Cytolytic/Cytotoxic Activity.
Int J Mol Sci;
25(6)2024 Mar 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38542105
2.
Boosting Cholesterol Efflux from Foam Cells by Sequential Administration of rHDL to Deliver MicroRNA and to Remove Cholesterol in a Triple-Cell 2D Atherosclerosis Model.
Small;
18(13): e2105915, 2022 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35156292
3.
Four Cholesterol-Recognition Motifs in the Pore-Forming and Translocation Domains of Adenylate Cyclase Toxin Are Essential for Invasion of Eukaryotic Cells and Lysis of Erythrocytes.
Int J Mol Sci;
23(15)2022 Aug 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35955837
4.
Phospholipase A activity of adenylate cyclase toxin mediates translocation of its adenylate cyclase domain.
Proc Natl Acad Sci U S A;
114(33): E6784-E6793, 2017 08 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28760979
5.
Pathophysiology of Type 2 Diabetes Mellitus.
Int J Mol Sci;
21(17)2020 Aug 30.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32872570
6.
Statin Treatment-Induced Development of Type 2 Diabetes: From Clinical Evidence to Mechanistic Insights.
Int J Mol Sci;
21(13)2020 Jul 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32630698
7.
Familial Hypercholesterolemia: The Most Frequent Cholesterol Metabolism Disorder Caused Disease.
Int J Mol Sci;
19(11)2018 Nov 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30388787
8.
Validation of LDLr Activity as a Tool to Improve Genetic Diagnosis of Familial Hypercholesterolemia: A Retrospective on Functional Characterization of LDLr Variants.
Int J Mol Sci;
19(6)2018 Jun 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29874871
9.
Reply to Masin et al: To be or not to be a phospholipase A.
Proc Natl Acad Sci U S A;
115(11): E2491, 2018 03 13.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29467295
10.
Functional characterization and classification of frequent low-density lipoprotein receptor variants.
Hum Mutat;
36(1): 129-41, 2015 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25378237
11.
Functional characterization of splicing and ligand-binding domain variants in the LDL receptor.
Hum Mutat;
33(1): 232-43, 2012 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21990180
12.
Bordetella adenylate cyclase toxin promotes calcium entry into both CD11b+ and CD11b- cells through cAMP-dependent L-type-like calcium channels.
J Biol Chem;
285(1): 357-64, 2010 Jan 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19875442
13.
Interdomain Ca(2+) effects in Escherichia coli alpha-haemolysin: Ca(2+) binding to the C-terminal domain stabilizes both C- and N-terminal domains.
Biochim Biophys Acta;
1798(6): 1225-33, 2010 Jun.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20223223
14.
Cholesterol stimulates the lytic activity of Adenylate Cyclase Toxin on lipid membranes by promoting toxin oligomerization and formation of pores with a greater effective size.
FEBS J;
288(23): 6795-6814, 2021 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34216517
15.
MLb-LDLr: A Machine Learning Model for Predicting the Pathogenicity of LDLr Missense Variants.
JACC Basic Transl Sci;
6(11): 815-827, 2021 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34869944
16.
Irreversible versus repairable membrane poration: differences in permeabilization elicited by Bordetella Adenylate Cyclase Toxin and its hemolysin domain in macrophages.
FEBS J;
287(9): 1798-1815, 2020 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31652486
17.
Cholesterol Efflux Efficiency of Reconstituted HDL Is Affected by Nanoparticle Lipid Composition.
Biomedicines;
8(10)2020 Sep 23.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32977626
18.
Mutation type classification and pathogenicity assignment of sixteen missense variants located in the EGF-precursor homology domain of the LDLR.
Sci Rep;
10(1): 1727, 2020 02 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32015373
19.
Membrane Permeabilization by Pore-Forming RTX Toxins: What Kind of Lesions Do These Toxins Form?
Toxins (Basel);
11(6)2019 06 18.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31216745
20.
Membrane Permeabilization by Bordetella Adenylate Cyclase Toxin Involves Pores of Tunable Size.
Biomolecules;
9(5)2019 05 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31083482