Detalhe da pesquisa
1.
Epitope editing enables targeted immunotherapy of acute myeloid leukaemia.
Nature;
621(7978): 404-414, 2023 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37648862
2.
Outcomes of hematopoietic stem cell gene therapy for Wiskott-Aldrich syndrome.
Blood;
142(15): 1281-1296, 2023 10 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37478401
3.
Scalable inference of cell differentiation networks in gene therapy clonal tracking studies of haematopoiesis.
Bioinformatics;
39(10)2023 10 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37774002
4.
A mixed-effects stochastic model reveals clonal dominance in gene therapy safety studies.
BMC Bioinformatics;
24(1): 228, 2023 Jun 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37268887
5.
A novel scan statistics approach for clustering identification and comparison in binary genomic data.
BMC Bioinformatics;
17(Suppl 11): 320, 2016 Sep 22.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28185547
6.
CRISPR-SURF: discovering regulatory elements by deconvolution of CRISPR tiling screen data.
Nat Methods;
15(12): 992-993, 2018 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30504875
7.
Prostaglandin E2 as transduction enhancer affects competitive engraftment of human hematopoietic stem and progenitor cells.
Mol Ther Methods Clin Dev;
31: 101131, 2023 Dec 14.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37920236
8.
Meeting FDA Guidance recommendations for replication-competent virus and insertional oncogenesis testing.
Mol Ther Methods Clin Dev;
28: 28-39, 2023 Mar 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36588821
9.
Clonal selection of hematopoietic stem cells after gene therapy for sickle cell disease.
Nat Med;
29(12): 3175-3183, 2023 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37973947
10.
Gene editing without ex vivo culture evades genotoxicity in human hematopoietic stem cells.
bioRxiv;
2023 May 27.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37292647
11.
High-definition mapping of retroviral integration sites identifies active regulatory elements in human multipotent hematopoietic progenitors.
Blood;
116(25): 5507-17, 2010 Dec 16.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20864581
12.
Estimated comparative integration hotspots identify different behaviors of retroviral gene transfer vectors.
PLoS Comput Biol;
7(12): e1002292, 2011 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22144885
13.
Gene Expression Profiling of Lymph Node Sub-Capsular Sinus Macrophages in Cancer.
Front Immunol;
12: 672123, 2021.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34168645
14.
Long-term lymphoid progenitors independently sustain naïve T and NK cell production in humans.
Nat Commun;
12(1): 1622, 2021 03 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33712608
15.
Preclinical Evaluation of a Novel Lentiviral Vector Driving Lineage-Specific BCL11A Knockdown for Sickle Cell Gene Therapy.
Mol Ther Methods Clin Dev;
17: 589-600, 2020 Jun 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32300607
16.
BCL11A enhancer-edited hematopoietic stem cells persist in rhesus monkeys without toxicity.
J Clin Invest;
130(12): 6677-6687, 2020 12 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32897878
17.
A comprehensive single cell transcriptional landscape of human hematopoietic progenitors.
Nat Commun;
10(1): 2395, 2019 06 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31160568
18.
Dynamics of genetically engineered hematopoietic stem and progenitor cells after autologous transplantation in humans.
Nat Med;
24(11): 1683-1690, 2018 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30275570
19.
In Vivo Tracking of Human Hematopoiesis Reveals Patterns of Clonal Dynamics during Early and Steady-State Reconstitution Phases.
Cell Stem Cell;
19(1): 107-19, 2016 07 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27237736
20.
Chromatin organization at the nuclear pore favours HIV replication.
Nat Commun;
6: 6483, 2015 Mar 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25744187