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Facile fabrication of novel three-dimensional anode materials to increase the bacterial loading capacity and improve substrate transport in microbial fuel cells (MFCs) is of great interest and importance. Herein, a novel graphene-containing foam (GCF) was fabricated easily by freeze-drying and pyrolysis of a graphene oxide-agarose gel. Owing to the involvement of graphene and stainless-steel mesh in the GCF, the GCF shows high electrical conductivity, enabling the GCF to be a conductive electrode for MFC applications. With the aid of agarose, the GCF electrode possesses a supermacroporous structure with pore sizes ranging from 100-200â µm and a high surface area, which greatly increase the bacterial loading capacity. Cell viability measurements indicate that the GCF possesses excellent biocompatibility. The MFC, equipped with a 0.4â mm-thick GCF anode, shows a maximum area power density of 786â mW m(-2) , which is 4.1 times that of a MFC equipped with a commercial carbon cloth anode. The simple fabrication route in combination with the outstanding electrochemical performance of the GCF indicates a promising anode for MFC applications.
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Fontes de Energia Bioelétrica/microbiologia , Grafite/química , Óxidos/química , Sefarose/química , Condutividade Elétrica , Eletrodos , Porosidade , Shewanella putrefaciens/citologia , Shewanella putrefaciens/crescimento & desenvolvimentoRESUMO
Poliomyelitis is an acute infectious disease caused by poliovirus. This bibliometric analysis aims to examine the status of poliomyelitis research in the past 20 years. Information regarding polio research was obtained from the Web of Science Core Collection database. CiteSpace, VOSviewer, and Excel were used to perform visual and bibliometric analysis with respect to countries/regions, institutions, authors, journals and keywords. A total of 5,335 publications on poliomyelitis were published from 2002 to 2021. The USA was the county with the majority of publications. Additionally, the most productive institution was the Centers for Disease Control and Prevention. Sutter, RW produced the most papers and had the most co-citations. Vaccine was the journal with the most polio-related publications and citations. The most common keywords were mainly about polio immunology research ("polio," "immunization," "children," "eradication" and "vaccine"). Our study is helpful for identifying research hotspots and providing direction for future research on poliomyelitis.
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Poliomielite , Poliovirus , Estados Unidos , Criança , Humanos , Poliomielite/prevenção & controle , Bibliometria , Centers for Disease Control and Prevention, U.S. , Bases de Dados FactuaisRESUMO
Objectives: To conduct a bibliometric analysis to quantify and identify the current status and trends of acromegaly research in the past two decades. Materials and methods: Articles related to acromegaly that were published from 1999 to 2022 were retrieved through the Web of Science core collection (WoSCC) database. Then, they were imported into VOSviewer and CiteSpace to conduct a visualization analysis of authors, countries, institutions, citation numbers, cocitations, keywords, and references. Results: A total of 3,909 articles were identified in the study. Among them, the United States made the largest contribution to the field. Moreover, Colao A. was the most prolific author, and the University of Naples Federico II was the institution with the most publications. In addition, the Journal of Clinical Endocrinology and Metabolism was the core journal in the field. High-frequency keywords mainly included "acromegaly," "GH (Growth Hormone)," "IGH-I (Insulin-Like Growth Factor I)," "pituitary adenomas," and "octreotide." Conclusion: Studies related to acromegaly have shown stable stepwise growth over the past two decades. Interestingly, the research focus after 2016 gradually shifted from the etiology, mechanism, medications for treatment, and complications to improving prognosis and quality of life of patients with acromegaly. The current findings may provide guidance for further research in the field of acromegaly.
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Objective: Pheochromocytoma is a rare catecholamine-producing neuroendocrine tumour originating from the chromaffin cells of the adrenal medulla or extra-adrenal paraganglia. However, there are few bibliometric studies on Pheochromocytoma. Therefore, this study was employed to summarize the global trends and current status in pheochromocytoma by bibliometric analysis. Materials and methods: The Web of Science (WOS) core collection database was searched for publications relating to pheochromocytoma from 2001 to 2021. Bibliometric analysis was used to examine the data, and Microsoft Excel was utilized to create bar graphs. In addition, VOSviewer was used to carry out co-authorship analysis, co-citation analysis and co-occurrence analysis. CiteSpace was used to analyze the keywords citation bursts. Results: A total of 8,653 publications published in 1,806 journals by 38,590 authors in 6,117 organizations from 100 countries/regions were included in our study. Among them, USA was the leading countries in terms of total publications and sum of time cited, whereas Eunice Kennedy Shriver Natl Inst Child Hlth & Hum was the leading institutions. The main publications for pheochromocytoma-related articles were Journal of clinical endocrinology &metabolism. Pacak karel and Eisenhofer Graeme were the main contributing authors. The studies on pheochromocytoma could be grouped into five clusters: Treatment, Mechanism, Etiology, Radiology and Hormones study. Moreover, the radiology study, etiology study and some specific keywords such germlines mutation, mesenchymal stem-cells, autophagy, neuroinflammation, neurotoxicity, and hemodynamic instability, may become the hot spots of future. Conclusion: Although the number of articles on pheochromocytoma has fluctuated slightly over the past 20 years, there has been an overall upward trend. In general, precision medicine research on pheochromocytoma, especially metastatic pheochromocytoma, in terms of diagnosis, treatment, and etiology will be a hot research topic in the future. This study helps to understand the research perspectives, hot spots and trends of pheochromocytoma and provide new insight and a basis for future pheochromocytoma research quickly.
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Neoplasias das Glândulas Suprarrenais , Medula Suprarrenal , Dermatite , Tumores Neuroendócrinos , Feocromocitoma , Criança , Humanos , BibliometriaRESUMO
OBJECTIVE: To generalize the research status, hotspots, and development trends of amputation-related research. METHODS: The data from 1999 to 2021 were collected from the Web of Science core collection database, and analyzed through bibliometrics software (CiteSpace and VOSviewer) for the dual-map overlay of journals, top 25 references with the strongest citation bursts, top 25 keywords with the strongest citation bursts, and timeline of keywords. RESULTS: A total of 8,588 literature studies were involved in this study. The United States ranks the first in terms of H-index, total number of publications, and total citations. US Department of Veterans Affairs, Veterans Health Administration, and University of Washington are the major contributors to amputation. Prosthetics and Orthotics International, Archives of Physical Medicine and Rehabilitation, and Journal of Rehabilitation Research and Development are the main publication channels for articles related to amputation. Geertzen JHB, Czerniecki J, and Dijkstra PU are major contributors to amputation. In addition, research on limb salvage treatment and surgical methods for amputation will become a hotspot in the future. CONCLUSION: The total number of publications for amputation has generally increased from 1999 to 2021. Our study is beneficial for scientists to specify the research hotspot and development direction of amputation.
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OBJECTIVE: The purpose of the study was to investigate the therapeutic effect and nursing satisfaction of bedside nursing combined with detail nursing in the gastroenterology department. METHODS: 112 patients with gastrointestinal diseases admitted to our hospital from November 2018 to November 2019 were selected as the study subjects and randomly divided into a research group (n = 56) and reference group (n = 56). The reference group received routine clinical nursing, while on this basis, the research group received bedside nursing combined with detail nursing. After that, the clinical nursing effects of the two groups were compared. RESULTS: There were no significant differences in sex ratio, age, BMI, smoking history, drinking history, marital status, and disease types between the two groups (P > 0.05). The VAS scores in the two groups after intervention were significantly lower than those before intervention (P < 0.01), and the VAS scores in the research group after intervention were significantly lower than those in the reference group (P < 0.01). The nursing ability, nursing skills, and nursing responsibility in the research group were significantly higher than those in the reference group (P < 0.01). There were no significant differences between the two groups in the number of patients who were satisfied and needed improvement (P > 0.05). Besides, the number of very satisfied cases in the research group was significantly higher than that in the reference group (P < 0.05), and the number of unsatisfied cases was significantly lower than that in the reference group (P < 0.05). The total incidence of clinical adverse events in the research group was significantly lower than that in the reference group (P < 0.01). The gastrointestinal diseases related knowledge scores after intervention were significantly higher than those before intervention (P < 0.01), and the gastrointestinal diseases related knowledge scores after intervention in the research group were significantly higher than those in the reference group (P < 0.01). The GQOLI-74 scores after intervention in the two groups were significantly higher than those before intervention (P < 0.01), and the GQOLI-74 scores after intervention in the research group were significantly higher than those in the reference group (P < 0.01). CONCLUSION: The application of bedside nursing mode combined with detail nursing in gastrointestinal diseases can effectively reduce patients' pains, as well as the incidence of clinical adverse events, and improve patients' life quality, with definite curative effect, which is worthy of promotion and application.
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A series of cobalt and heteroatom (N and/or S) doped carbon materials were prepared and explored as electrocatalysts for hydrogen evolution reaction (HER). The most active catalyst is a Co-, N-, and S-tridoped carbon (CoNS-C), which was prepared through heat treatment of nitrogen- and sulfur-enriched poly(m-aminobenzenesulfonic acid) and cobalt(II) nitrate, followed by acid leaching. The presence of cobalt-heteroatom complexes in CoNS-C is confirmed and identified as highly active molecule catalytic centers for HER. The overpotential of CoNS-C is 180 mV at 10 mA cm(-2) in 0.5 M aqueous H2SO4. Besides the high HER activity, the CoNS-C also shows excellent durability and can be produced readily in large quantities. This work may have provided a new and simple route in the design and batch-synthesis of highly active and durable carbonaceous electrocatalysts for HER.