Detalhe da pesquisa
1.
Increased human complement pathway regulatory protein gene dose is associated with increased endothelial expression and prolonged survival during ex-vivo perfusion of GTKO pig lungs with human blood.
Xenotransplantation;
30(4): e12812, 2023.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37504492
2.
Expression of human thrombomodulin by GalTKO.hCD46 pigs modulates coagulation cascade activation by endothelial cells and during ex vivo lung perfusion with human blood.
Xenotransplantation;
30(6): e12828, 2023.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37767640
3.
Pig-to-baboon lung xenotransplantation: Extended survival with targeted genetic modifications and pharmacologic treatments.
Am J Transplant;
22(1): 28-45, 2022 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34424601
4.
Effects of human TFPI and CD47 expression and selectin and integrin inhibition during GalTKO.hCD46 pig lung perfusion with human blood.
Xenotransplantation;
29(2): e12725, 2022 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35234315
5.
hEPCR.hTBM.hCD47.hHO-1 with donor clodronate and DDAVP treatment improves perfusion and function of GalTKO.hCD46 porcine livers perfused with human blood.
Xenotransplantation;
29(2): e12731, 2022 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35166407
6.
Stable expression of the human thrombomodulin transgene in pig endothelial cells is associated with a reduction in the inflammatory response.
Cytokine;
148: 155580, 2021 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34099346
7.
Humanized von Willebrand factor reduces platelet sequestration in ex vivo and in vivo xenotransplant models.
Xenotransplantation;
28(6): e12712, 2021 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34657336
8.
Thromboxane and histamine mediate PVR elevation during xenogeneic pig lung perfusion with human blood.
Xenotransplantation;
26(2): e12458, 2019 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30175863
9.
P- and E-selectin receptor antagonism prevents human leukocyte adhesion to activated porcine endothelial monolayers and attenuates porcine endothelial damage.
Xenotransplantation;
25(2): e12381, 2018 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29359469
10.
Synthetic liver function is detectable in transgenic porcine livers perfused with human blood.
Xenotransplantation;
25(1)2018 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29067741
11.
Transgenic expression of human leukocyte antigen-E attenuates GalKO.hCD46 porcine lung xenograft injury.
Xenotransplantation;
24(2)2017 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28258595
12.
Immunological and physiological observations in baboons with life-supporting genetically engineered pig kidney grafts.
Xenotransplantation;
24(2)2017 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28303661
13.
The role of genetically engineered pigs in xenotransplantation research.
J Pathol;
238(2): 288-99, 2016 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26365762
14.
Meta-analysis of the independent and cumulative effects of multiple genetic modifications on pig lung xenograft performance during ex vivo perfusion with human blood.
Xenotransplantation;
22(2): 102-11, 2015.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25470239
15.
Glucose metabolism in pigs expressing human genes under an insulin promoter.
Xenotransplantation;
22(1): 70-9, 2015.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25382150
16.
Pig kidney graft survival in a baboon for 136 days: longest life-supporting organ graft survival to date.
Xenotransplantation;
22(4): 302-9, 2015.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26130164
17.
Pig-to-baboon heterotopic heart transplantation--exploratory preliminary experience with pigs transgenic for human thrombomodulin and comparison of three costimulation blockade-based regimens.
Xenotransplantation;
22(3): 211-20, 2015.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25847282
18.
Regulation of human platelet aggregation by genetically modified pig endothelial cells and thrombin inhibition.
Xenotransplantation;
21(1): 72-83, 2014.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24188473
19.
Human dominant-negative class II transactivator transgenic pigs - effect on the human anti-pig T-cell immune response and immune status.
Immunology;
140(1): 39-46, 2013 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23566228
20.
Clinical lung xenotransplantation--what donor genetic modifications may be necessary?
Xenotransplantation;
19(3): 144-58, 2012.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22702466