Detalhe da pesquisa
1.
Non-canonical role of Hippo tumor suppressor serine/threonine kinase 3 STK3 in prostate cancer.
Mol Ther;
30(1): 485-500, 2022 01 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34450249
2.
Towards the Development of an In vivo Chemical Probe for Cyclin G Associated Kinase (GAK).
Molecules;
24(22)2019 Nov 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31698822
3.
Mild, Pd-catalyzed stannylation of radioiodination targets.
Bioorg Med Chem Lett;
25(8): 1761-1764, 2015 Apr 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25777268
4.
Illuminating the understudied GPCR-ome.
Drug Discov Today;
29(3): 103848, 2024 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38052317
5.
Virtual Screening of a Chemically Diverse "Superscaffold" Library Enables Ligand Discovery for a Key GPCR Target.
ACS Chem Biol;
19(4): 866-874, 2024 04 19.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38598723
6.
Sandmeyer reaction repurposed for the site-selective, non-oxidizing radioiodination of fully-deprotected peptides: studies on the endogenous opioid peptide α-neoendorphin.
Bioorg Med Chem Lett;
23(15): 4347-50, 2013 Aug 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23796454
7.
Identification of Pyrimidine-Based Lead Compounds for Understudied Kinases Implicated in Driving Neurodegeneration.
J Med Chem;
65(2): 1313-1328, 2022 01 27.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34333981
8.
Design, Synthesis, and Characterization of [18F]mG2P026 as a High-Contrast PET Imaging Ligand for Metabotropic Glutamate Receptor 2.
J Med Chem;
65(14): 9939-9954, 2022 07 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35802702
9.
Synthesis and Characterization of 5-(2-Fluoro-4-[11C]methoxyphenyl)-2,2-dimethyl-3,4-dihydro-2H-pyrano[2,3-b]pyridine-7-carboxamide as a PET Imaging Ligand for Metabotropic Glutamate Receptor 2.
J Med Chem;
65(3): 2593-2609, 2022 02 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35089713
10.
Temozolomide-induced guanine mutations create exploitable vulnerabilities of guanine-rich DNA and RNA regions in drug-resistant gliomas.
Sci Adv;
8(25): eabn3471, 2022 06 24.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35731869
11.
Towards a RIOK2 chemical probe: cellular potency improvement of a selective 2-(acylamino)pyridine series.
RSC Med Chem;
12(1): 129-136, 2021 Jan 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34046605
12.
Development of a potent and selective chemical probe for the pleiotropic kinase CK2.
Cell Chem Biol;
28(4): 546-558.e10, 2021 04 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33484635
13.
Predilection for developing a hematogenous orthopaedic implant-associated infection in older versus younger mice.
J Orthop Surg Res;
16(1): 556, 2021 Sep 14.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34521424
14.
A Chemical Probe for Dark Kinase STK17B Derives Its Potency and High Selectivity through a Unique P-Loop Conformation.
J Med Chem;
63(23): 14626-14646, 2020 12 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33215924
15.
Quantifying CDK inhibitor selectivity in live cells.
Nat Commun;
11(1): 2743, 2020 06 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32488087
16.
SGC-AAK1-1: A Chemical Probe Targeting AAK1 and BMP2K.
ACS Med Chem Lett;
11(3): 340-345, 2020 Mar 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32184967
17.
Molecularly specific detection of bacterial lipoteichoic acid for diagnosis of prosthetic joint infection of the bone.
Bone Res;
6: 13, 2018.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29707402
18.
Mouse model of Gram-negative prosthetic joint infection reveals therapeutic targets.
JCI Insight;
3(17)2018 09 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30185667
19.
Noninvasive optical and nuclear imaging of Staphylococcus-specific infection with a human monoclonal antibody-based probe.
Virulence;
9(1): 262-272, 2018 01 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29166841
20.
Fatty acid oxidation by the osteoblast is required for normal bone acquisition in a sex- and diet-dependent manner.
JCI Insight;
2(16)2017 Aug 17.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28814665