Detalhe da pesquisa
1.
DPP8 and DPP9 inhibition induces pro-caspase-1-dependent monocyte and macrophage pyroptosis.
Nat Chem Biol;
13(1): 46-53, 2017 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27820798
2.
A high-throughput, multiplexed assay for superfamily-wide profiling of enzyme activity.
Nat Chem Biol;
10(8): 656-63, 2014 Aug.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24997602
3.
Preclinical Development of PNT6555, a Boronic Acid-Based, Fibroblast Activation Protein-α (FAP)-Targeted Radiotheranostic for Imaging and Treatment of FAP-Positive Tumors.
J Nucl Med;
65(1): 100-108, 2024 Jan 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38050111
4.
4-Substituted boro-proline dipeptides: synthesis, characterization, and dipeptidyl peptidase IV, 8, and 9 activities.
Bioorg Med Chem Lett;
22(17): 5536-40, 2012 Sep 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22853995
5.
Inhibition of Dpp8/9 Activates the Nlrp1b Inflammasome.
Cell Chem Biol;
25(3): 262-267.e5, 2018 03 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29396289
6.
Synthesis and characterization of constrained peptidomimetic dipeptidyl peptidase IV inhibitors: amino-lactam boroalanines.
J Med Chem;
50(10): 2391-8, 2007 May 17.
Artigo
em Inglês
| MEDLINE
| ID: mdl-17458948
7.
Identification of selective and potent inhibitors of fibroblast activation protein and prolyl oligopeptidase.
J Med Chem;
56(9): 3467-77, 2013 May 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23594271
8.
Quantitation of fibroblast activation protein (FAP)-specific protease activity in mouse, baboon and human fluids and organs.
FEBS Open Bio;
4: 43-54, 2013.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24371721
9.
Pro-soft Val-boroPro: a strategy for enhancing in vivo performance of boronic acid inhibitors of serine proteases.
J Med Chem;
54(7): 2022-8, 2011 Apr 14.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21388136
10.
Chemical and biological evaluation of dipeptidyl boronic acid proteasome inhibitors for use in prodrugs and pro-soft drugs targeting solid tumors.
J Med Chem;
54(13): 4365-77, 2011 Jul 14.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21634429