Detalhe da pesquisa
1.
UTX inhibition as selective epigenetic therapy against TAL1-driven T-cell acute lymphoblastic leukemia.
Genes Dev;
30(5): 508-21, 2016 Mar 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26944678
2.
Intra-articular Injection of a B Cell Depletion Antibody Enhances Local Exposure to the Joint-Draining Lymph Node in Mice with Collagen-Induced Arthritis.
Mol Pharm;
20(4): 2053-2066, 2023 04 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36945772
3.
Increasing Linker Chain Length and Intestinal Stability Enhances Lymphatic Transport and Lymph Node Exposure of Triglyceride Mimetic Prodrugs of a Model Immunomodulator Mycophenolic Acid.
Mol Pharm;
20(5): 2675-2685, 2023 05 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36996486
4.
A lipid-anchored neurokinin 1 receptor antagonist prolongs pain relief by a three-pronged mechanism of action targeting the receptor at the plasma membrane and in endosomes.
J Biol Chem;
296: 100345, 2021.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33515548
5.
Polymeric Nanotubes as Drug Delivery VectorsâComparison of Covalently and Supramolecularly Assembled Constructs.
Biomacromolecules;
23(6): 2315-2328, 2022 06 13.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35582852
6.
Biocompatible Cationic Lipoamino Acids as Counterions for Oral Administration of API-Ionic Liquids.
Pharm Res;
39(10): 2405-2419, 2022 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35661084
7.
micro-RNA-486-5p protects against kidney ischemic injury and modifies the apoptotic transcriptome in proximal tubules.
Kidney Int;
100(3): 597-612, 2021 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34181969
8.
Digestion of Lipid-Based Formulations Not Only Mediates Changes to Absorption of Poorly Soluble Drugs Due to Differences in Solubilization But Also Reflects Changes to Thermodynamic Activity and Permeability.
Mol Pharm;
18(4): 1768-1778, 2021 04 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33729806
9.
Lipophilic Salts and Lipid-Based Formulations: Enhancing the Oral Delivery of Octreotide.
Pharm Res;
38(6): 1125-1137, 2021 Jun.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34100217
10.
Molecular Dynamics Simulations and Experimental Results Provide Insight into Clinical Performance Differences between Sandimmune® and Neoral® Lipid-Based Formulations.
Pharm Res;
38(9): 1531-1547, 2021 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34561814
11.
Protease-activated receptor-2 in endosomes signals persistent pain of irritable bowel syndrome.
Proc Natl Acad Sci U S A;
115(31): E7438-E7447, 2018 07 31.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30012612
12.
A ligand-induced structural change in fatty acid-binding protein 1 is associated with potentiation of peroxisome proliferator-activated receptor α agonists.
J Biol Chem;
294(10): 3720-3734, 2019 03 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30598509
13.
Organ-specific lymphatics play distinct roles in regulating HDL trafficking and composition.
Am J Physiol Gastrointest Liver Physiol;
318(4): G725-G735, 2020 04 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32068443
14.
Sex diversity in proximal tubule and endothelial gene expression in mice with ischemic acute kidney injury.
Clin Sci (Lond);
134(14): 1887-1909, 2020 07 31.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32662516
15.
High-Density Lipoprotein Composition Influences Lymphatic Transport after Subcutaneous Administration.
Mol Pharm;
17(8): 2938-2951, 2020 08 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32543863
16.
Quantifying In Vivo Luminal Drug Solubilization -Supersaturation-Precipitation Profiles to Explain the Performance of Lipid Based Formulations.
Pharm Res;
37(3): 47, 2020 Feb 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32016597
17.
Cis-regulatory determinants of MyoD function.
Nucleic Acids Res;
46(14): 7221-7235, 2018 08 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30016497
18.
Endosomal signaling of the receptor for calcitonin gene-related peptide mediates pain transmission.
Proc Natl Acad Sci U S A;
114(46): 12309-12314, 2017 11 14.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29087309
19.
Pointing in the Right Direction: Controlling the Orientation of Proteins on Nanoparticles Improves Targeting Efficiency.
Nano Lett;
19(3): 1827-1831, 2019 03 13.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30773887
20.
Lymphatic Uptake of Liposomes after Intraperitoneal Administration Primarily Occurs via the Diaphragmatic Lymphatics and is Dependent on Liposome Surface Properties.
Mol Pharm;
16(12): 4987-4999, 2019 12 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31625752