Detalhe da pesquisa
1.
Recommendations for empowering early career researchers to improve research culture and practice.
PLoS Biol;
20(7): e3001680, 2022 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35797414
2.
Progressive emergence of an S153F plus R263K combination of integrase mutations in the proviral DNA of one individual successfully treated with dolutegravir.
J Antimicrob Chemother;
76(3): 639-647, 2021 02 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33184634
3.
Identification of a Pyridoxine-Derived Small-Molecule Inhibitor Targeting Dengue Virus RNA-Dependent RNA Polymerase.
Antimicrob Agents Chemother;
60(1): 600-8, 2016 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26574011
4.
Differential effects of the G118R, H51Y, and E138K resistance substitutions in different subtypes of HIV integrase.
J Virol;
89(6): 3163-75, 2015 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25552724
5.
Characterization of the Drug Resistance Profiles of Integrase Strand Transfer Inhibitors in Simian Immunodeficiency Virus SIVmac239.
J Virol;
89(23): 12002-13, 2015 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26378179
6.
Subtype-specific analysis of the K65R substitution in HIV-1 that confers hypersusceptibility to a novel nucleotide-competing reverse transcriptase inhibitor.
Antimicrob Agents Chemother;
59(6): 3189-96, 2015.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25779585
7.
Dolutegravir maintains a durable effect against HIV replication in tissue culture even after drug washout.
J Antimicrob Chemother;
70(10): 2810-5, 2015 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26142476
8.
Effect of HIV-1 integrase resistance mutations when introduced into SIVmac239 on susceptibility to integrase strand transfer inhibitors.
J Virol;
88(17): 9683-92, 2014 Sep 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24920794
9.
A resveratrol analog termed 3,3',4,4',5,5'-hexahydroxy-trans-stilbene is a potent HIV-1 inhibitor.
J Med Virol;
87(12): 2054-60, 2015 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25989218
10.
The M50I polymorphic substitution in association with the R263K mutation in HIV-1 subtype B integrase increases drug resistance but does not restore viral replicative fitness.
Retrovirology;
11: 7, 2014 Jan 17.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24433497
11.
HIV-1 group O integrase displays lower enzymatic efficiency and higher susceptibility to raltegravir than HIV-1 group M subtype B integrase.
Antimicrob Agents Chemother;
58(12): 7141-50, 2014 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25224008
12.
Addition of E138K to R263K in HIV integrase increases resistance to dolutegravir, but fails to restore activity of the HIV integrase enzyme and viral replication capacity.
J Antimicrob Chemother;
69(10): 2733-40, 2014 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24917583
13.
Upper Airway Epithelial Tissue Transcriptome Analysis Reveals Immune Signatures Associated with COVID-19 Severity in Ghanaians.
J Immunol Res;
2024: 6668017, 2024.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38375062
14.
Automethylation of protein arginine methyltransferase 6 (PRMT6) regulates its stability and its anti-HIV-1 activity.
Retrovirology;
10: 73, 2013 Jul 17.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23866860
15.
Viral fitness cost prevents HIV-1 from evading dolutegravir drug pressure.
Retrovirology;
10: 22, 2013 Feb 22.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23432922
16.
Biochemical analysis of the role of G118R-linked dolutegravir drug resistance substitutions in HIV-1 integrase.
Antimicrob Agents Chemother;
57(12): 6223-35, 2013 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24080645
17.
Evolution of HIV integrase resistance mutations.
Curr Opin Infect Dis;
26(1): 43-9, 2013 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23242340
18.
In vitro and structural evaluation of PL-100 as a potential second-generation HIV-1 protease inhibitor.
J Antimicrob Chemother;
68(1): 105-12, 2013 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22945918
19.
Characterization of the R263K mutation in HIV-1 integrase that confers low-level resistance to the second-generation integrase strand transfer inhibitor dolutegravir.
J Virol;
86(5): 2696-705, 2012 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22205735
20.
Subunit-selective mutational analysis and tissue culture evaluations of the interactions of the E138K and M184I mutations in HIV-1 reverse transcriptase.
J Virol;
86(16): 8422-31, 2012 Aug.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22623801