Detalhe da pesquisa
1.
Targeting progesterone signaling prevents metastatic ovarian cancer.
Proc Natl Acad Sci U S A;
117(50): 31993-32004, 2020 12 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33262282
2.
Prostacyclin post-treatment improves LPS-induced acute lung injury and endothelial barrier recovery via Rap1.
Biochim Biophys Acta;
1852(5): 778-91, 2015 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25545047
3.
The Ras-related protein, Rap1A, mediates thrombin-stimulated, integrin-dependent glioblastoma cell proliferation and tumor growth.
J Biol Chem;
289(25): 17689-98, 2014 Jun 20.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24790104
4.
Activation of Rap1 inhibits NADPH oxidase-dependent ROS generation in retinal pigment epithelium and reduces choroidal neovascularization.
FASEB J;
28(1): 265-74, 2014 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24043260
5.
Mammalian target of rapamycin complex 1 (mTORC1) enhances bortezomib-induced death in tuberous sclerosis complex (TSC)-null cells by a c-MYC-dependent induction of the unfolded protein response.
J Biol Chem;
288(22): 15687-98, 2013 May 31.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23612979
6.
Cutting edge: NADPH oxidase modulates MHC class II antigen presentation by B cells.
J Immunol;
189(8): 3800-4, 2012 Oct 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22984083
7.
Cyclic AMP-Rap1A signaling activates RhoA to induce α(2c)-adrenoceptor translocation to the cell surface of microvascular smooth muscle cells.
Am J Physiol Cell Physiol;
303(5): C499-511, 2012 Sep 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22621783
8.
PRL-1 protein promotes ERK1/2 and RhoA protein activation through a non-canonical interaction with the Src homology 3 domain of p115 Rho GTPase-activating protein.
J Biol Chem;
286(49): 42316-42324, 2011 Dec 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22009749
9.
M-Ras induces Ral and JNK activation to regulate MEK/ERK-independent gene expression in MCF-7 breast cancer cells.
J Cell Biochem;
113(4): 1253-64, 2012 Apr.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22121046
10.
Human TSC-associated renal angiomyolipoma cells are hypersensitive to ER stress.
Am J Physiol Renal Physiol;
303(6): F831-44, 2012 Sep 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22791333
11.
Cool-1/ßPIX functions as a guanine nucleotide exchange factor in the cycling of Cdc42 to regulate insulin secretion.
Am J Physiol Endocrinol Metab;
301(6): E1072-80, 2011 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21828338
12.
The Rac effector p67phox regulates phagocyte NADPH oxidase by stimulating Vav1 guanine nucleotide exchange activity.
Mol Cell Biol;
27(1): 312-23, 2007 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-17060455
13.
Rap1 promotes cell spreading by localizing Rac guanine nucleotide exchange factors.
J Cell Biol;
167(1): 111-22, 2004 Oct 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-15479739
14.
E-cadherin dis-engagement activates the Rap1 GTPase.
J Cell Biochem;
105(4): 1027-37, 2008 Nov 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-18767072
15.
New insights into the mechanisms of SOS activation.
Sci STKE;
2007(414): pe67, 2007 Nov 27.
Artigo
em Inglês
| MEDLINE
| ID: mdl-18042941
16.
Crk proteins transduce FGF signaling to promote lens fiber cell elongation.
Elife;
72018 01 23.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29360039
17.
Rac2, a hematopoiesis-specific Rho GTPase, specifically regulates mast cell protease gene expression in bone marrow-derived mast cells.
Mol Cell Biol;
22(21): 7645-57, 2002 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-12370311
18.
AND-34 activates phosphatidylinositol 3-kinase and induces anti-estrogen resistance in a SH2 and GDP exchange factor-like domain-dependent manner.
Mol Cancer Res;
3(1): 32-41, 2005 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-15671247
19.
Specificity and expression of RalGPS as RalGEFs.
Methods Enzymol;
407: 108-14, 2006.
Artigo
em Inglês
| MEDLINE
| ID: mdl-16757318
20.
Characterization of AND-34 function and signaling.
Methods Enzymol;
407: 55-63, 2006.
Artigo
em Inglês
| MEDLINE
| ID: mdl-16757314