Detalhe da pesquisa
1.
Addendum: The antibody aducanumab reduces Aß plaques in Alzheimer's disease.
Nature;
546(7659): 564, 2017 06 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28640269
2.
The antibody aducanumab reduces Aß plaques in Alzheimer's disease.
Nature;
537(7618): 50-6, 2016 09 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27582220
3.
Structure of the LINGO-1-anti-LINGO-1 Li81 antibody complex provides insights into the biology of LINGO-1 and the mechanism of action of the antibody therapy.
J Pharmacol Exp Ther;
350(1): 110-23, 2014 Jul.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24756303
4.
Dynamic analysis of amyloid ß-protein in behaving mice reveals opposing changes in ISF versus parenchymal Aß during age-related plaque formation.
J Neurosci;
31(44): 15861-9, 2011 Nov 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22049429
5.
Dissociation between the processivity and total activity of γ-secretase: implications for the mechanism of Alzheimer's disease-causing presenilin mutations.
Biochemistry;
50(42): 9023-35, 2011 Oct 25.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21919498
6.
Structural and functional dissection of the Abp1 ADFH actin-binding domain reveals versatile in vivo adapter functions.
Mol Biol Cell;
16(7): 3128-39, 2005 Jul.
Artigo
em Inglês
| MEDLINE
| ID: mdl-15872087
7.
A high-affinity interaction with ADP-actin monomers underlies the mechanism and in vivo function of Srv2/cyclase-associated protein.
Mol Biol Cell;
15(11): 5158-71, 2004 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-15356265
8.
A central role for the WH2 domain of Srv2/CAP in recharging actin monomers to drive actin turnover in vitro and in vivo.
Cytoskeleton (Hoboken);
67(2): 120-33, 2010 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20169536
9.
Reconstitution and dissection of the 600-kDa Srv2/CAP complex: roles for oligomerization and cofilin-actin binding in driving actin turnover.
J Biol Chem;
284(16): 10923-34, 2009 Apr 17.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19201756
10.
Mechanism and biological role of profilin-Srv2/CAP interaction.
J Cell Sci;
120(Pt 7): 1225-34, 2007 Apr 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-17376963