Detalhe da pesquisa
1.
Mechanism, cellular functions and cancer roles of polymerase-theta-mediated DNA end joining.
Nat Rev Mol Cell Biol;
23(2): 125-140, 2022 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34522048
2.
The molecular basis and disease relevance of non-homologous DNA end joining.
Nat Rev Mol Cell Biol;
21(12): 765-781, 2020 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33077885
3.
Sequential requirements for distinct Polθ domains during theta-mediated end joining.
Mol Cell;
84(8): 1460-1474.e6, 2024 Apr 18.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38640894
4.
Retrotransposons hijack alt-EJ for DNA replication and eccDNA biogenesis.
Nature;
620(7972): 218-225, 2023 Aug.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37438532
5.
Stepwise requirements for polymerases δ and θ in theta-mediated end joining.
Nature;
623(7988): 836-841, 2023 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37968395
6.
Essential Roles for Polymerase θ-Mediated End Joining in the Repair of Chromosome Breaks.
Mol Cell;
63(4): 662-673, 2016 08 18.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27453047
7.
DNA polymerase theta suppresses mitotic crossing over.
PLoS Genet;
17(3): e1009267, 2021 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33750946
8.
Marker-free quantification of repair pathway utilization at Cas9-induced double-strand breaks.
Nucleic Acids Res;
49(9): 5095-5105, 2021 05 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33963863
9.
Mechanistic basis for microhomology identification and genome scarring by polymerase theta.
Proc Natl Acad Sci U S A;
117(15): 8476-8485, 2020 04 14.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32234782
10.
Unexpected behavior of DNA polymerase Mu opposite template 8-oxo-7,8-dihydro-2'-guanosine.
Nucleic Acids Res;
47(17): 9410-9422, 2019 09 26.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31435651
11.
Structural accommodation of ribonucleotide incorporation by the DNA repair enzyme polymerase Mu.
Nucleic Acids Res;
45(15): 9138-9148, 2017 Sep 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28911097
12.
Polµ tumor variants decrease the efficiency and accuracy of NHEJ.
Nucleic Acids Res;
45(17): 10018-10031, 2017 Sep 29.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28973441
13.
Bridging of double-stranded breaks by the nonhomologous end-joining ligation complex is modulated by DNA end chemistry.
Nucleic Acids Res;
45(4): 1872-1878, 2017 02 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27924007
14.
Substrate preference of Gen endonucleases highlights the importance of branched structures as DNA damage repair intermediates.
Nucleic Acids Res;
45(9): 5333-5348, 2017 May 19.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28369583
15.
Reversal of DNA damage induced Topoisomerase 2 DNA-protein crosslinks by Tdp2.
Nucleic Acids Res;
44(8): 3829-44, 2016 05 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27060144
16.
Essential role for polymerase specialization in cellular nonhomologous end joining.
Proc Natl Acad Sci U S A;
112(33): E4537-45, 2015 Aug 18.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26240371
17.
Organization and dynamics of the nonhomologous end-joining machinery during DNA double-strand break repair.
Proc Natl Acad Sci U S A;
112(20): E2575-84, 2015 May 19.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25941401
18.
Mechanism of suppression of chromosomal instability by DNA polymerase POLQ.
PLoS Genet;
10(10): e1004654, 2014 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25275444
19.
Ku is a 5'-dRP/AP lyase that excises nucleotide damage near broken ends.
Nature;
464(7292): 1214-7, 2010 Apr 22.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20383123
20.
Requirements for 5'dRP/AP lyase activity in Ku.
Nucleic Acids Res;
42(17): 11136-43, 2014.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25200085