Detalhe da pesquisa
1.
A Tension-Based Model Distinguishes Hypertrophic versus Dilated Cardiomyopathy.
Cell;
165(5): 1147-1159, 2016 May 19.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27114035
2.
Incomplete-penetrant hypertrophic cardiomyopathy MYH7 G256E mutation causes hypercontractility and elevated mitochondrial respiration.
Proc Natl Acad Sci U S A;
121(19): e2318413121, 2024 May 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38683993
3.
Integrating comparative modeling and accelerated simulations reveals conformational and energetic basis of actomyosin force generation.
Proc Natl Acad Sci U S A;
120(9): e2215836120, 2023 02 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36802417
4.
Structural OFF/ON transitions of myosin in relaxed porcine myocardium predict calcium-activated force.
Proc Natl Acad Sci U S A;
120(5): e2207615120, 2023 01 31.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36696446
5.
A complete biomechanical model of Hydra contractile behaviors, from neural drive to muscle to movement.
Proc Natl Acad Sci U S A;
120(11): e2210439120, 2023 03 14.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36897982
6.
The biochemically defined super relaxed state of myosin-A paradox.
J Biol Chem;
300(1): 105565, 2024 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38103642
7.
MBNL1 Regulates Programmed Postnatal Switching Between Regenerative and Differentiated Cardiac States.
Circulation;
2024 Mar 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38426339
8.
Slower Calcium Handling Balances Faster Cross-Bridge Cycling in Human MYBPC3 HCM.
Circ Res;
132(5): 628-644, 2023 03 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36744470
9.
Danicamtiv Increases Myosin Recruitment and Alters Cross-Bridge Cycling in Cardiac Muscle.
Circ Res;
133(5): 430-443, 2023 08 18.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37470183
10.
MYBPC3-c.772G>A mutation results in haploinsufficiency and altered myosin cycling kinetics in a patient induced stem cell derived cardiomyocyte model of hypertrophic cardiomyopathy.
J Mol Cell Cardiol;
191: 27-39, 2024 Jun.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38648963
11.
Incorporating Diversity, Equity, and Inclusion Content Into Bioengineering Curricula: A Program-Level Approach.
J Biomech Eng;
146(5)2024 Mar 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37851545
12.
dATP elevation induces myocardial metabolic remodeling to support improved cardiac function.
J Mol Cell Cardiol;
175: 1-12, 2023 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36470336
13.
Exploring the super-relaxed state of myosin in myofibrils from fast-twitch, slow-twitch, and cardiac muscle.
J Biol Chem;
298(3): 101640, 2022 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35090895
14.
The harder the climb the better the view: The impact of substrate stiffness on cardiomyocyte fate.
J Mol Cell Cardiol;
166: 36-49, 2022 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35139328
15.
Thick filament activation is different in fast- and slow-twitch skeletal muscle.
J Physiol;
600(24): 5247-5266, 2022 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36342015
16.
Cardiac myosin activation with 2-deoxy-ATP via increased electrostatic interactions with actin.
Proc Natl Acad Sci U S A;
116(23): 11502-11507, 2019 06 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31110001
17.
Effect of Myosin Isoforms on Cardiac Muscle Twitch of Mice, Rats and Humans.
Int J Mol Sci;
23(3)2022 Jan 20.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35163054
18.
The effect of variable troponin C mutation thin filament incorporation on cardiac muscle twitch contractions.
J Mol Cell Cardiol;
155: 112-124, 2021 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33636222
19.
Increasing Fatty Acid Oxidation Prevents High-Fat Diet-Induced Cardiomyopathy Through Regulating Parkin-Mediated Mitophagy.
Circulation;
142(10): 983-997, 2020 09 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32597196
20.
Modulation of post-powerstroke dynamics in myosin II by 2'-deoxy-ADP.
Arch Biochem Biophys;
699: 108733, 2021 03 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33388313