Detalhe da pesquisa
1.
Activation of the transcription factor NFAT5 in the tumor microenvironment enforces CD8+ T cell exhaustion.
Nat Immunol;
24(10): 1645-1653, 2023 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37709986
2.
Structure-based optimization of type III indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors.
J Enzyme Inhib Med Chem;
37(1): 1773-1811, 2022 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35758198
3.
1,2,3-Triazoles as inhibitors of indoleamine 2,3-dioxygenase 2 (IDO2).
Bioorg Med Chem Lett;
26(17): 4330-3, 2016 09 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27469130
4.
Telomerase inhibitors from cyanobacteria: isolation and synthesis of sulfoquinovosyl diacylglycerols from Microcystis aeruguinosa PCC 7806.
Chemistry;
19(14): 4596-601, 2013 Apr 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23364876
5.
A lentiviral vector for the production of T cells with an inducible transgene and a constitutively expressed tumour-targeting receptor.
Nat Biomed Eng;
7(9): 1063-1080, 2023 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37069267
6.
TCR sequencing and cloning methods for repertoire analysis and isolation of tumor-reactive TCRs.
Cell Rep Methods;
3(4): 100459, 2023 04 24.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37159666
7.
The non-coding RNA TERRA is a natural ligand and direct inhibitor of human telomerase.
Nucleic Acids Res;
38(17): 5797-806, 2010 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20460456
8.
A cell-based phenotypic library selection and screening approach for the de novo discovery of novel functional chimeric antigen receptors.
Sci Rep;
12(1): 1136, 2022 01 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35064152
9.
VEGFR-2 redirected CAR-T cells are functionally impaired by soluble VEGF-A competition for receptor binding.
J Immunother Cancer;
9(8)2021 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34389616
10.
Azole-Based Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitors.
J Med Chem;
64(4): 2205-2227, 2021 02 25.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33557523
11.
A computationally designed chimeric antigen receptor provides a small-molecule safety switch for T-cell therapy.
Nat Biotechnol;
38(4): 426-432, 2020 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32015549
12.
Author Correction: A computationally designed chimeric antigen receptor provides a small-molecule safety switch for T-cell therapy.
Nat Biotechnol;
38(4): 503, 2020 Apr.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32127717
13.
Protein RNA and protein protein interactions mediate association of human EST1A/SMG6 with telomerase.
Nucleic Acids Res;
35(20): 7011-22, 2007.
Artigo
em Inglês
| MEDLINE
| ID: mdl-17940095
14.
CD8 Binding of MHC-Peptide Complexes in cis or trans Regulates CD8+ T-cell Responses.
J Mol Biol;
431(24): 4941-4958, 2019 12 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31704286
15.
A human homolog of yeast Est1 associates with telomerase and uncaps chromosome ends when overexpressed.
Curr Biol;
13(7): 568-74, 2003 Apr 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-12676087
16.
Methods for the ex vivo characterization of human CD8+ T subsets based on gene expression and replicative history analysis.
Methods Mol Med;
109: 265-84, 2005.
Artigo
em Inglês
| MEDLINE
| ID: mdl-15585927
17.
Induction of interleukin-2 receptor alpha (IL-2Ralpha) expression by interleukin-2: important role of the interleukin-2 receptor beta chain region between the two Stat5 docking sites.
Eur Cytokine Netw;
13(3): 331-9, 2002.
Artigo
em Inglês
| MEDLINE
| ID: mdl-12231477
18.
Telomere length homeostasis responds to changes in intracellular dNTP pools.
Genetics;
193(4): 1095-105, 2013 Apr.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23335335
19.
Specific binding of telomeric G-quadruplexes by hydrosoluble perylene derivatives inhibits repeat addition processivity of human telomerase.
Biochimie;
94(3): 854-63, 2012 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22182489
20.
Molecular dissection of telomeric repeat-containing RNA biogenesis unveils the presence of distinct and multiple regulatory pathways.
Mol Cell Biol;
30(20): 4808-17, 2010 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20713443